{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T16:33:26Z","timestamp":1772555606366,"version":"3.50.1"},"reference-count":34,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,5,15]],"date-time":"2025-05-15T00:00:00Z","timestamp":1747267200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Public Health"],"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>This study aimed to investigate the factors influencing depression and anxiety in individuals with schizophrenia during the COVID-19 pandemic, with the goal of providing evidence to support strategies for improving emotional disturbances during the pandemic.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A cross-sectional study was conducted among 159 outpatients with schizophrenia between January and June 2023. Data were collected using a self-developed sociodemographic questionnaire, the Chinese version of the Illness Perception Questionnaire-Revised (IPQ-R), the Patient Health Questionnaire-9 (PHQ-9), and the 7-item Generalized Anxiety Disorder scale (GAD-7). Regression analysis was performed using SPSS version 27.0 to identify the factors associated with depression and anxiety.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Timeline cyclical and treatment control were significant predictors of depression among individuals with schizophrenia (R<jats:sup>2<\/jats:sup>\u202f=\u202f0.160, <jats:italic>p<\/jats:italic>\u202f&amp;lt;\u202f0.01). Additionally, timeline cyclical and the presence of chronic comorbidities significantly predicted anxiety (R<jats:sup>2<\/jats:sup>\u202f=\u202f0.217, <jats:italic>p<\/jats:italic>\u202f&amp;lt;\u202f0.01).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Illness perception concerning COVID-19 significantly influenced the severity of depression and anxiety in individuals with schizophrenia. Addressing these perceptions serves as an essential component of interventions aimed at improving mental health outcomes during the pandemic.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fpubh.2025.1583630","type":"journal-article","created":{"date-parts":[[2025,5,15]],"date-time":"2025-05-15T04:12:15Z","timestamp":1747282335000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Influence of illness perception on depression and anxiety in individuals with schizophrenia during the COVID-19 pandemic"],"prefix":"10.3389","volume":"13","author":[{"given":"Meng","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan-Feng","family":"Deng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2025,5,15]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"1972","DOI":"10.1002\/cpp.2767","article-title":"The Italian COVID-19 anxiety syndrome scale: investigation of the COVID-19 anxiety syndrome and its association with psychological symptoms in an Italian population","volume":"29","author":"Mansueto","year":"2022","journal-title":"Clin Psychol Psychother"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"1083","DOI":"10.1002\/cpp.2860","article-title":"The Arab COVID-19 anxiety syndrome scale (C-19ASS): COVID-19 anxiety syndrome and psychological symptoms in the Saudi Arabian 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