{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T10:56:26Z","timestamp":1789728986194,"version":"4.0.1"},"reference-count":40,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,8,15]],"date-time":"2025-08-15T00:00:00Z","timestamp":1755216000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Public Health"],"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>Respiratory diseases, including influenza (flu) and respiratory syncytial virus, continue to be major health concerns globally. The onset of COVID-19 further compounded these issues, making it important to examine public attitudes toward vaccination and understanding of respiratory diseases. This study explores factors influencing decisions to receive the latest COVID-19 vaccine, focusing specifically on the role of prior respiratory illness diagnosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A follow-up survey among 299 participants from Southeastern Louisiana across 10 healthcare facilities was administered via phone and the Qualtrics platform, gathering information about the likelihood of receiving the latest COVID-19 vaccine. Quantitative data were analyzed using log-binomial and Poisson regression models to assess relationships between respiratory illness history and COVID-19 vaccine acceptance.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Nearly half (47%) of the participants reported a history of respiratory illness. Individuals with prior respiratory diagnosis were more likely to accept the latest COVID-19 vaccine (62%) than those without (41%) (RR: 1.79, 95% CI: 1.26\u20132.56). In fully adjusted models, accounting for age, prior vaccine hesitancy, and comorbidities, influenza vaccine acceptance (RR: 1.87, 95% CI: 1.06\u20133.28) was associated with greater likelihood of receiving the latest COVID-19 vaccine. Key barriers to vaccination, including concerns about side effects and distrust in vaccine efficacy were identified.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Participants with respiratory illnesses and those with positive vaccination histories, particularly regarding influenza, showed a higher likelihood of accepting the latest COVID-19 vaccines. However, significant obstacles to vaccine uptake persist. Tailored public health efforts that address these concerns are crucial to improving vaccine rates, particularly among hesitant groups.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fpubh.2025.1593861","type":"journal-article","created":{"date-parts":[[2025,8,15]],"date-time":"2025-08-15T05:27:47Z","timestamp":1755235667000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":4,"title":["Influence of respiratory disease experiences on COVID-19 vaccine acceptance: a study from Southeastern Louisiana"],"prefix":"10.3389","volume":"13","author":[{"given":"Saba","family":"Barri","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Al-Dahir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klaus","family":"Heyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashley","family":"Taylor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alaa","family":"Khalil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed","family":"Belkhouche","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brooke-Ashleigh","family":"Bonvillain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathryn","family":"Caldwell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heather","family":"Surcouf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ibrahim","family":"Hamed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malack","family":"Jwayyed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leslie 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