{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T12:56:35Z","timestamp":1789563395397,"version":"build-2803163510"},"reference-count":41,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T00:00:00Z","timestamp":1758240000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Public Health"],"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Despite expanded antiretroviral therapy (ART) coverage in China, AIDS remains a major public health challenge. This study aimed to assess survival outcomes and identify factors influencing survival time among HIV\/AIDS patients receiving ART.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This study was a retrospective cohort study utilizing data on HIV patients receiving antiretroviral therapy in Jiulongpo District, Chongqing, from 2012 to 2022. Life tables estimated cumulative survival, Kaplan-Meyer compared survival between groups, and accelerated time to failure (AFT) modeling was used for analysis of factors influencing survival time.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The 1-, 3-, 5-, and 10-year cumulative survival rates were 94% (95% CI: 0.93 to 0.95), 90% (95% CI: 0.89 to 0.91), 86% (95% CI: 0.85 to 0.87), and 79% (95% CI: 0.76 to 0.81), respectively. Compared to patients aged 15\u201329, those aged 30\u201349 (TR\u202f=\u202f0.22, 95% CI: 0.11 to 0.46, <jats:italic>p<\/jats:italic>\u202f&amp;lt;\u202f0.01) and \u226550 (TR\u202f=\u202f0.07, 95% CI: 0.03 to 0.15, <jats:italic>p<\/jats:italic>\u202f&amp;lt;\u202f0.01) had shorter survival. Males (TR\u202f=\u202f0.26, 95% CI: 0.17 to 0.38, <jats:italic>p<\/jats:italic>\u202f&amp;lt;\u202f0.01), single (TR\u202f=\u202f0.52, 95% CI: 0.33 to 0.84, <jats:italic>p<\/jats:italic>\u202f=\u202f0.007), and divorced\/widowed patients (TR\u202f=\u202f0.67, 95% CI: 0.48 to 0.93, <jats:italic>p<\/jats:italic>\u202f=\u202f0.018) had shorter survival compared to their counterparts. Infection via homosexual contact (TR\u202f=\u202f0.21, 95% CI: 0.12 to 0.37, <jats:italic>p<\/jats:italic>\u202f&amp;lt;\u202f0.01), injection drug use\/other routes (TR\u202f=\u202f0.09, 95% CI: 0.04 to 0.20, <jats:italic>p<\/jats:italic>\u202f&amp;lt;\u202f0.01) was associated with shorter survival than heterosexual contact. Patients with tertiary (TR\u202f=\u202f5.88, 95% CI: 3.05 to 11.33, <jats:italic>p<\/jats:italic>\u202f&amp;lt;\u202f0.01), high school (TR\u202f=\u202f2.86, 95% CI: 1.87 to 4.36, <jats:italic>p<\/jats:italic>\u202f&amp;lt;\u202f0.01), and middle school education (TR\u202f=\u202f1.93, 95% CI: 1.40 to 2.67, <jats:italic>p<\/jats:italic>\u202f=\u202f0.002) had longer survival than those with primary\/illiterate education. Baseline CD4 counts of \u2265350 (TR\u202f=\u202f3.26, 95% CI: 2.33 to 4.55, <jats:italic>p<\/jats:italic>\u202f&amp;lt;\u202f0.01) and 200\u2013349 cells\/\u03bcL (TR\u202f=\u202f2.73, 95% CI: 1.90 to 3.92, <jats:italic>p<\/jats:italic>\u202f&amp;lt;\u202f0.01) were linked to longer survival compared to 0\u2013199 cells\/\u03bcL.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Older age, males, lower educational attainment, homosexual contact, injection of drugs, and lower baseline CD4 levels are influential factors for shorter survival time in HIV\/AIDS patients receiving ART. These findings may help inform clinical decision-making and targeted interventions to improve the long-term outcomes of people living with HIV.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fpubh.2025.1614619","type":"journal-article","created":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T05:30:46Z","timestamp":1758259846000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":3,"title":["Survival analysis and factors influencing survival time of adult HIV\/AIDS patients receiving antiretroviral therapy from 2012 to 2022 in Chongqing, China: a retrospective cohort study"],"prefix":"10.3389","volume":"13","author":[{"given":"Yao","family":"Huang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinhua","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lihong","family":"Mu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2025,9,19]]},"reference":[{"key":"ref1","year":""},{"key":"ref2","doi-asserted-by":"publisher","first-page":"225","DOI":"10.13419\/j.cnki.aids.2024.03.01","article-title":"National AIDS STD epidemic, December 2023","volume":"30","year":"2024","journal-title":"Chin J AIDS 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