{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T17:20:30Z","timestamp":1783099230316,"version":"3.54.6"},"reference-count":35,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100019717","name":"AstraZeneca Espa\u00f1a","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100019717","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Public Health"],"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Vaccines against seasonal influenza represent the best option to reduce the cases and severity of the disease in children under 5 years. In Spain, the Region of Murcia was a pioneer in implementing universal vaccination at schools. The study aimed to evaluate the acceptance and attitudes of parents of children of 6\u201359 months old toward influenza vaccination and factors associated with parents' decision to vaccinate their children during the 2023\u20132024 campaign.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This prospective, descriptive study used a questionnaire to collect data from parents of vaccinated (VC) and non-vaccinated children (nVC). VC received either the live-attenuated intranasal vaccine (LAIV) or the intramuscular vaccine (IIV) depending on their age.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Parent's self-vaccination\/intention in this campaign (OR: 8.51) and in the previous one (OR: 4.49), and children's compliance with vaccination schedule (OR: 7.83) were the main factors associated with the probability of children being vaccinated against influenza. The main reason for vaccinating was to protect the child (IIV: 92.5% vs. LAIV: 91.0%), while waiting for further experience with the vaccine (21.0%) and lack of recommendation from the healthcare professional (20.4%) were the major reasons for not vaccinating. Most vaccinating parents (IIV: 90.4% vs. LAIV: 93.9%, <jats:italic>p<\/jats:italic> &amp;lt; 0.001) were satisfied with the vaccine. Among VC at school, 95.8% of parents were satisfied and 97.4% would recommend for family and friends.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Parents of VC, especially those vaccinated with LAIV at schools, were highly satisfied with the vaccine. Parent's influenza vaccination status and children's compliance with vaccination schedule were determinant for parent's decision to vaccinate children under 5 years old. More information about influenza vaccination could help increase vaccination rates in these children.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fpubh.2025.1644600","type":"journal-article","created":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T05:52:09Z","timestamp":1759297929000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":3,"title":["Vaccinating and non-vaccinating parents' attitudes toward influenza vaccination in children under 5 years old in Spain"],"prefix":"10.3389","volume":"13","author":[{"given":"Matilde","family":"Zornoza-Moreno","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susana","family":"S\u00e1nchez-Manresa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Cruz","family":"G\u00f3mez-Moreno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Pilar","family":"Ros Abell\u00e1n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaime J.","family":"P\u00e9rez-Mart\u00edn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2025,10,1]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"693","DOI":"10.1016\/S0140-6736(22)00982-5","article-title":"Influenza","volume":"400","author":"Uyeki","year":"2022","journal-title":"Lancet."},{"key":"B2","unstructured":"Influenza (seasonal)\n          \n          2025"},{"key":"B3","doi-asserted-by":"publisher","first-page":"e497","DOI":"10.1016\/S2214-109X(19)30545-5","article-title":"Global burden of respiratory infections associated with seasonal influenza in children under 5 years in 2018: a systematic review and modelling study","volume":"8","author":"Wang","year":"2020","journal-title":"Lancet Glob Health."},{"key":"B4","article-title":"Salud Carlos III","author":"Instituto","year":"2023","journal-title":"Vigilancia Centinela de Infecci\u00f3n Respiratoria Aguda en Atenci\u00f3n Primaria (IRAS) y en Hospitales (IRAG) Gripe, COVID-19 y otros Virus Respiratorios Madrid"},{"key":"B5","first-page":"461","article-title":"Vaccines against influenza WHO position paper \u2013 November 2012","volume":"87","year":"2012","journal-title":"Wkly Epidemiol Rec"},{"key":"B6","volume-title":"ECDC scientific advice on seasonal influenza vaccination of children and pregnant women","year":"2012"},{"key":"B7","article-title":"Recomendaciones de vacunaci\u00f3n frente a gripe en poblaci\u00f3n infantil de 6 a 59 meses","author":"Grupo de trabajo de Recomendaciones de Vacunaci\u00f3n frente a gripe en poblaci\u00f3n infantil de 6 a 59 meses de la Ponencia de Programa y Registro de","year":"2022"},{"key":"B8","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1016\/j.anpede.2022.11.002","article-title":"Immunisation schedule of the Spanish association of paediatrics: 2023 recommendations","volume":"98","author":"\u00c1lvarez Garc\u00eda","year":"2023","journal-title":"An Pediatr"},{"key":"B9","doi-asserted-by":"publisher","first-page":"438","DOI":"10.1016\/j.anpede.2024.04.016","article-title":"Vaccination against seasonal flu in childhood and adolescence. 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