{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T21:44:56Z","timestamp":1778708696402,"version":"3.51.4"},"reference-count":32,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,12,16]],"date-time":"2025-12-16T00:00:00Z","timestamp":1765843200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Public Health"],"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To investigate HIV epidemiological characteristics and risk factors among international migrants (including Chinese citizens departing\/returning and foreign nationals entering China) at Sichuan International Travel Health Care Center (2004\u20132024), informing targeted prevention strategies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective analysis of HIV infections was conducted using ELISA screening and Western blot confirmation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Out of 566,475 individuals screened, 323 were found to be positive, resulting in a positivity rate of 0.057% (95% CI: 0.049\u20130.065). The characteristics of the infected individuals were as follows: (1) the majority were male (92.57%), predominantly aged between 41 and 50 years (29.33%), and primarily comprised migrant workers (59.49%); (2) the CRF55_01B subtype was the most prevalent, accounting for 60.61%, and exhibited an independent transmission chain; (3) heterosexual transmission was the primary mode of infection (47.68%), with 74.37% of individuals not maintaining consistent condom use. Additionally, there has been an increasing trend in the proportion of individuals aged 51\u201360 and those with a college education or higher in recent years.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>A comprehensive review of two decades of data indicates the necessity for port-focused interventions aimed at middle-aged migrant workers, improved surveillance measures, and the incorporation of molecular epidemiology into prevention strategies. Interventions should be specifically tailored to prioritize evidence-based approaches for high-risk groups, particularly mobile workers aged 51\u201360 years and university students engaging in unprotected sexual activities.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fpubh.2025.1681756","type":"journal-article","created":{"date-parts":[[2025,12,16]],"date-time":"2025-12-16T06:28:17Z","timestamp":1765866497000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Spatiotemporal trends of HIV among international migrants: a 20-year surveillance study at Sichuan Ports, China"],"prefix":"10.3389","volume":"13","author":[{"given":"Ying","family":"Shi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qing","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lvbo","family":"Tian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuelong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan","family":"Long","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2025,12,16]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"489","DOI":"10.1016\/S0140-6736(06)69157-5","article-title":"HIV\/AIDS epidemiology, pathogenesis, prevention, and 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