{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T06:40:52Z","timestamp":1764744052323,"version":"3.46.0"},"reference-count":80,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T00:00:00Z","timestamp":1764720000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Public Health"],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Post-COVID syndrome is a complex condition affecting patients after SARS-CoV-2 infection. It is characterized by fatigue, pain, reduced resilience, and quality of life. Severe cases resemble myalgic encephalomyelitis\/chronic fatigue syndrome (ME\/CFS), associated with post-exertional malaise (PEM). Due to the unknown etiology and lack of curative options, multimodal therapy offers a particularly promising approach to symptom management.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This qualitative interview study was part of a mixed-methods project conducted in 2022\u20132023, which investigated the effects of a multimodal integrative day clinic approach (MICOM day clinic) on the symptoms and general well-being of individuals with Post-COVID syndrome. The aim of the qualitative sub-study was to gain a deeper understanding of the individual perspectives of patients on their experiences of the illness and the perceived changes reported by 20 intervention group participants after completing the 11-week (66-h) multimodal program. Interview data had been analyzed based on reflexive thematic analysis using MAXQDA software.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Participants reported significant impairments in daily life and work capacity, accompanied by high psychological burden. The multimodal program led to improvements in physical and mental symptoms, overall well-being, and self-efficacy. Patients also reported long-term lifestyle changes in areas such as nutrition, stress regulation, and performance-oriented physical activity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Post-COVID syndrome poses ongoing challenges for individuals and healthcare systems. Multimodal integrative treatment can effectively reduce symptoms, enhance coping strategies, and promote sustainable self-care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical trial registration<\/jats:title>\n                    <jats:p>\n                      <jats:ext-link>Clinicaltrials.gov<\/jats:ext-link>\n                      , identifier NCT05630378.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fpubh.2025.1688592","type":"journal-article","created":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T06:39:03Z","timestamp":1764743943000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Integrative multimodal treatment approach for patients suffering from Post-COVID syndrome: a study based on qualitative interviews with individuals participating in an 11-week\u202fday clinic program"],"prefix":"10.3389","volume":"13","author":[{"given":"Christine","family":"Uecker","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoph","family":"Schlee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandra","family":"Utz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah","family":"Schmid","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jost","family":"Langhorst","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2025,12,3]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"1093","DOI":"10.1007\/s00103-021-03394-x","article-title":"Die verschiedenen Phasen der COVID-19-Pandemie in Deutschland: Eine deskriptive Analyse von Januar 2020 bis 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