{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T20:49:13Z","timestamp":1790455753452,"version":"4.1.0"},"reference-count":37,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T00:00:00Z","timestamp":1765756800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Public Health"],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Reliable national transfusion services require continuous surveillance of donation activity, inventory losses, transfusion-transmissible infection (TTI) screening, and immunohematology workload. Kuwait\u2019s centralized service is coordinated by the Kuwait Central Blood Bank (KCBB).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study design and methods<\/jats:title>\n                    <jats:p>We performed a retrospective analysis of officially requested KCBB annual reports (January 2019\u2013December 2023). Collated variables included donation volumes, donor sex and ABO\/RhD distribution, discarded components, and NAT screening outcomes for HBV, HCV, and HIV. Patient-side indicators comprised total immunohematology samples, antibody screening\/identification, antenatal testing, and alloantibody profiles. The analysis was descriptive, presenting distributions and temporal trends without inferential testing.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Donations averaged ~82,000 annually, with a decline during the COVID-19 pandemic (2020\u20132021) and recovery to ~85,000 in 2023. Male donors accounted for &amp;gt;85% of donations. O RhD\n                      <jats:sup>+<\/jats:sup>\n                      positive (38.7%) and B RhD\n                      <jats:sup>+<\/jats:sup>\n                      positive (23.7%) were the most common blood groups, while RhD-negative donors comprised 8.6%. Wastage varied yearly, predominantly impacting fresh frozen plasma. NAT-reactive TTI prevalence remained low: HBV 0.06\u20130.11% (60\u2013110 per 100,000), HCV 0.03\u20130.08% (30\u201380 per 100,000), and HIV 0.02\u20130.05% (20\u201350 per 100,000) annually. Immunohematology workload (total samples and test activity) fell during 2020\u20132021 and increased again by 2023. A wide spectrum of clinically significant alloantibodies was identified, most frequently within the Rh, Kell, and Kidd systems, with additional MNS and P1PK specificities. Among antenatal samples, antibody positivity averaged 3.8% (peak 4.7% in 2021); anti-D predominated, followed by anti-K.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>KCBB data highlight persistent male predominance among donors, RhD-negative scarcity (8.6%), and variable component wastage, especially FFP. These findings support targeted donor-recruitment strategies, obstetric\u2013transfusion planning for RhD-negative supply, and strengthened inventory management to improve resilience and safety of Kuwait\u2019s blood supply.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fpubh.2025.1714693","type":"journal-article","created":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T06:27:43Z","timestamp":1765780063000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Blood bank trends in Kuwait: five-year analysis of donations and investigations"],"prefix":"10.3389","volume":"13","author":[{"given":"Dalal","family":"Almuaili","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rabaa","family":"Abdullah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anwar 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