{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T08:26:48Z","timestamp":1771921608541,"version":"3.50.1"},"reference-count":29,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T00:00:00Z","timestamp":1771891200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Public Health"],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The number of patients with hyperuricemia and gout is constantly rising and the conditions are seriously affecting their quality of life. Thus, it is of great importance to identify a assessment scale to assess the quality of life suitable for the Chinese population. The aim of this study was to evaluate the health-related quality of life (HRQoL) of patients with hyperuricemia and gout in Tianjin, using the Short Form of 6-Dimensions Health 2nd version (SF-6Dv2) scale, and to explore its influencing factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A total of 171 patients who visited the hyperuricemia gout clinic in a Class III and Grade A hospital were collected from September 2022 to May 2024. The SF-6Dv2 scale was completed by face-to-face interview and its utility value was measured. Sex- and age-matched individuals from the community and a healthy population on physical examination from the same hospital served as the control group. This study compared the HRQoL of respondents through the SF-6Dv2 score and explored its influencing factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 171 patients (mean [SD] age: 45.34 [16.60] years) and 171 respondents (mean [SD] age: 41.24[16.60] years) from the control population were included. The mean utility value of the disease group was 0.671 (0.270), which was significantly lower than that of the control group (0.803 [0.155],\n                      <jats:italic>p<\/jats:italic>\n                      \u202f&amp;lt;\u202f0.001). In terms of physical function, role limitation, social function, pain, mental health, and vitality, patients reported worse quality of life than the control group. The results of multiple linear regression analysis showed that patients with normal triglyceride levels, who disliked seafood, had single marital status, and mild hyperuricemia with gout had higher health utility value.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study found that the utility value of the SF-6Dv2 scale for patients with hyperuricemia was lower than that of the control group. Furthermore, the level of triglycerides, the preference for seafood, the severity of hyperuricemia and gout, and marital status of the patients were correlated with the HRQoL of the patients with hyperuricemia and gout. This findings of this study have important practical value.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fpubh.2026.1744513","type":"journal-article","created":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T06:47:30Z","timestamp":1771915650000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Assessment of health-related quality of life of patients with gout and hyperuricemia in the Tianjin area according to the SF-6Dv2 scale"],"prefix":"10.3389","volume":"14","author":[{"given":"Xiaohui","family":"Zheng","sequence":"first","affiliation":[{"name":"Department of Pharmacy, Tianjin Union Medical Center, The First Affiliated Hospital of Nankai University","place":["Tianjin, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Baoyu","family":"Wang","sequence":"additional","affiliation":[{"name":"Endocrinology Department, Tianjin Union Medical Center, The First Affiliated Hospital of Nankai University","place":["Tianjin, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhuang","family":"Cui","sequence":"additional","affiliation":[{"name":"School of Public Health, Tianjin Medical University","place":["Tianjin, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shi-Tong","family":"Xie","sequence":"additional","affiliation":[{"name":"School of Pharmaceutical Science and Technology, Tianjin University","place":["Tianjin, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhenying","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Tianjin Union Medical Center, The First Affiliated Hospital of Nankai University","place":["Tianjin, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2026,2,24]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"101723","DOI":"10.1016\/j.berh.2021.101723","article-title":"Role of diet in hyperuricemia and gout","volume":"35","author":"Danve","year":"2021","journal-title":"Best Pract Res Clin Rheumatol"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"e001623","DOI":"10.1136\/rmdopen-2021-001623","article-title":"Gout, hyperuricaemia and crystal-associated disease network (G-CAN) common language definition of gout","volume":"7","author":"Murdoch","year":"2021","journal-title":"RMD Open"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3760\/cma.j.issn.1000-6699.2020.01.001","article-title":"Guideline for the diagnosis and management of hyperuricemiaand gout in China (2019)","volume":"36","year":"2020","journal-title":"Chin J Endocrinol Metab"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"791983","DOI":"10.3389\/fimmu.2021.791983","article-title":"Prevalence of hyperuricemia among Chinese adults: findings from two nationally representative cross-sectional surveys in 2015-16 and 2018-19","volume":"12","author":"Zhang","year":"2022","journal-title":"Front Immunol"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"43917","DOI":"10.1136\/bmjopen-2020-043917","article-title":"Temporal trends in hyperuricaemia among adults in Wuhan city","volume":"11","author":"Wan","year":"2010","journal-title":"BMJ Open"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1186\/s12986-021-00590-z","article-title":"Independent and joint associations of body mass index, waist circumference, waist-height ratio and their changes with risks of hyperuricemia in middle-aged and olderChinese individuals: a population-based nationwide cohort study","volume":"18","author":"Zhou","year":"2021","journal-title":"Nutr Metab"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"683","DOI":"10.2147\/CLEP.S403314","article-title":"Association between serum uric acid and non-alcoholic fattyliver disease: an updated systematic review and meta-analysis","volume":"15","author":"Sun","year":"2023","journal-title":"Clin Epidemiol"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"1569","DOI":"10.1016\/s0277-9536(98)00009-4","article-title":"The World Health Organization quality of life assessment (WHOQOL): development and general psychometric properties","volume":"46","year":"1998","journal-title":"Soc Sci Med (1967)"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"846","DOI":"10.1016\/j.jval.2020.12.014","article-title":"The unfolding method to explore health-related quality of life constructs in a Chinese general population","volume":"24","author":"Mao","year":"2021","journal-title":"Value Health"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1007\/s41669-020-00212-z","article-title":"Do rural residents in China understand EQ-5D-5L as intended? 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