{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T17:15:33Z","timestamp":1788542133062,"version":"build-2803163510"},"reference-count":74,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T00:00:00Z","timestamp":1772582400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Public Health"],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>China\u2019s healthcare system is confronting a rising burden of antimicrobial resistance, chronic complex diseases, and an aging population requiring long-term, post-acute care. As a value-based care model in the USA for over 50\u202fyears, home infusion therapy (HIT), combined with home health services (HHS), presents a sustainable alternative to prolonged hospitalization for intravenous medication administration. In this two-part narrative review, Part 1 provides a needs assessment describing the demographic, clinical, and public health factors driving the demand for HIT and HHS in China.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a literature search up to January 2026 using MEDLINE, EMBASE, PubMed, Web of Science, and China National Knowledge Infrastructure.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In Part 1, we present the impact of the aging population and chronic conditions requiring prolonged infusion therapy (including cancer, malnutrition and infections like osteomyelitis, endocarditis, and bacteremia) on the rising antimicrobial resistance, hospital burden and healthcare expenditures. Through the patient-centric solution of HIT and HHS, patients can receive intravenous medications and nutrition in the comfort of their homes, enabling the continuity of care beyond the hospital. Services include outpatient parenteral antibiotic therapy, hospice and palliative care in patients with cancer, and management of nutritional needs through total parenteral nutrition. Under this care model, reimbursement is tied to success in improved patient outcomes and reduced hospital readmissions. A detailed reimbursement and cost-effectiveness considerations are addressed in Part 2 of this review.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>With proper infrastructure development and reimbursement mechanisms that align payment with value, HIT and HHS could mitigate antimicrobial resistance, and transform and sustain affordable care delivery in China, especially for older adults and those with chronic conditions.<\/jats:p>\n                    <jats:p>\n                      Part 2 is available at\n                      <jats:ext-link>https:\/\/doi.org\/10.3389\/fpubh.2026.1761870<\/jats:ext-link>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fpubh.2026.1761871","type":"journal-article","created":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T14:59:24Z","timestamp":1772636364000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Transforming long-term post-acute care for the aging population through home infusion therapy in China: an assessment of need and demand (Part 1)"],"prefix":"10.3389","volume":"14","author":[{"given":"Wei","family":"Zuo","sequence":"first","affiliation":[{"name":"Department of Pharmacy, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences","place":["Beijing, China"]},{"name":"Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego","place":["La Jolla, CA, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zi Yin","family":"Zhou","sequence":"additional","affiliation":[{"name":"Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego","place":["La Jolla, CA, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dylan H.","family":"Do","sequence":"additional","affiliation":[{"name":"Dartmouth College","place":["Hanover, NH, United States"]},{"name":"Tylan Health","place":["El Monte, CA, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Austin-Phong","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Tylan Health","place":["El Monte, CA, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Connie","family":"Vo","sequence":"additional","affiliation":[{"name":"Tylan Health","place":["El Monte, CA, United States"]},{"name":"Comfort Home Health & Hospice Care Inc.","place":["Long Beach, CA, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tu","family":"Tran","sequence":"additional","affiliation":[{"name":"Tylan Health","place":["El Monte, CA, United States"]},{"name":"Huntington Hospital","place":["Pasadena, CA, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Mei","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaohong","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shan","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Medicine Intensive Care Unit, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianchun","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Clinical Nutrition, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luke","family":"Hoang","sequence":"additional","affiliation":[{"name":"Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego","place":["La Jolla, CA, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle T.","family":"Le","sequence":"additional","affiliation":[{"name":"Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego","place":["La Jolla, CA, United States"]},{"name":"Tylan Health","place":["El Monte, CA, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franco W. 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Dis"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"370","DOI":"10.37201\/req\/011.2022","article-title":"Efficacy and safety of outpatient parenteral antibiotic therapy in patients with infective endocarditis: a meta-analysis","volume":"35","author":"Wen","year":"2022","journal-title":"Rev Esp Quimioter"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1002\/agm2.70028","article-title":"Cancer burden in Chinese older adults: insights into incidence, mortality, and global comparisons using GLOBOCAN 2022","volume":"8","author":"Zheng","year":"2025","journal-title":"Aging Med"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"174","DOI":"10.1002\/hpm.3858","article-title":"Does outpatient mutual-aid reduce oncology patients\u2019 utilization of inpatient services?\u2014An empirical study of outpatient mutual-aid policy in Wuhan, China","volume":"40","author":"Jiang","year":"2025","journal-title":"Int J Health Plann 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parenteral and enteral nutrition in geriatric patients in China","volume":"3","author":"Zhu","year":"2020","journal-title":"Aging Med."},{"key":"ref42","doi-asserted-by":"publisher","first-page":"1348214","DOI":"10.3389\/fpubh.2024.1348214","article-title":"Influencing factors of home hospice care needs of the older adults with chronic diseases at the end of life in China: a cross-sectional study","volume":"12","author":"Wang","year":"2024","journal-title":"Front Public Health"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"1731","DOI":"10.2147\/CIA.S477877","article-title":"Construction of a home hospice care program for older adults at the end of life with chronic diseases in China: a Delphi method","volume":"19","author":"Wang","year":"2024","journal-title":"Clin Interv Aging"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"117186","DOI":"10.1016\/j.socscimed.2024.117186","article-title":"Maneuvering between cultures: the reception of hospice care in the 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model","year":""},{"key":"ref56","doi-asserted-by":"publisher","first-page":"3","DOI":"10.70776\/FSCX6194","article-title":"Cost savings: home versus inpatient infusion therapy, a review of the literature","volume":"2","author":"Haines","year":"2023","journal-title":"Infus J"},{"key":"ref57","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1016\/j.hjdsi.2016.04.004","article-title":"Home infusion: safe, clinically effective, patient preferred, and cost saving","volume":"5","author":"Polinski","year":"2017","journal-title":"Healthcare"},{"key":"ref58","volume-title":"Home infusion therapy: differences between medicare and private insurers\u2019 coverage","year":"2010"},{"key":"ref59","doi-asserted-by":"publisher","first-page":"ofac525","DOI":"10.1093\/ofid\/ofac525","article-title":"A primer on home infusion administration methods","volume":"9","author":"Loriaux","year":"2022","journal-title":"Open Forum Infect 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