{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T14:02:01Z","timestamp":1792677721810,"version":"4.5.0"},"reference-count":29,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T00:00:00Z","timestamp":1775520000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Public Health"],"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Microplastics (MPs) are emerging contaminants that raise concerns due to their potential health effects on vulnerable neonates who may be exposed to medical devices.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This prospective study investigated the presence of MPs in neonatal blood in relation to parenteral nutrition (PN) duration. A total of 12 neonates were categorized into long-term (&amp;gt;14 days), short-term (3\u20137 days), and non-exposed control groups. MPs were analyzed using confocal micro-Raman spectroscopy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Polyethylene accounted for 95.65% of particles detected in all blood samples. MP abundance was significantly higher in the long-term PN group compared to both short-term and control groups (\n                      <jats:italic>p<\/jats:italic>\n                      \u202f&amp;lt;\u202f0.05), demonstrating a dose\u2013response relationship with PN duration. Notably, larger MPs (&amp;gt;60 \u03bcm) were found exclusively in the long-term group.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>These preliminary findings, derived from a small sample cohort, suggest that the PN system may serve as a potential iatrogenic source of MPs for neonates.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical trial registration<\/jats:title>\n                    <jats:p>NCT07326761.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fpubh.2026.1767555","type":"journal-article","created":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T08:47:57Z","timestamp":1775551677000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Microplastics in neonates: an overlooked cost of parenteral nutrition"],"prefix":"10.3389","volume":"14","author":[{"given":"Debo","family":"Xu","sequence":"first","affiliation":[{"name":"Department of Pediatrics, The Affiliated Guangdong Second Provincial General Hospital of Jinan University","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenyu","family":"Liang","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, The Affiliated Guangdong Second Provincial General Hospital of Jinan University","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiaohuan","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, The Affiliated Guangdong Second Provincial General Hospital of Jinan University","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, The Affiliated Guangdong Second Provincial General Hospital of Jinan University","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huiyi","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, The Affiliated Guangdong Second Provincial General Hospital of Jinan University","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuming","family":"You","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, The Affiliated Guangdong Second Provincial General Hospital of Jinan University","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiong","family":"Meng","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, The Affiliated Guangdong Second Provincial General Hospital of Jinan University","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, The Affiliated Guangdong Second Provincial General Hospital of Jinan University","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,4,7]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"789","DOI":"10.3390\/ijerph20010789","article-title":"Microplastics in fish and fishery products and risks forhuman health: a review","volume":"20","author":"Alberghini","year":"2022","journal-title":"Int J Environ Res Public Health"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"838","DOI":"10.1126\/science.1094559","article-title":"Lost at sea: where is all the 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