{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T07:03:03Z","timestamp":1779692583008,"version":"3.53.1"},"reference-count":36,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T00:00:00Z","timestamp":1779667200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Public Health"],"abstract":"\n Background<\/jats:title>\n Emerging infectious diseases (EIDs) continue to pose recurrent challenges to global health systems. Nurses, as frontline healthcare professionals, play a pivotal role in early detection, infection control, and patient management. Mpox (monkeypox) outbreaks provide a real-world stress test for evaluating nurses\u2019 preparedness for EIDs. This study assessed Chinese nurses\u2019 knowledge and attitudes toward Mpox and examined training- and professional-related determinants of preparedness.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n A national online cross-sectional survey was conducted among nurses in China between January and March 2024 using convenience sampling. The questionnaire covered demographic characteristics, Mpox-related knowledge (27 items), and attitudes (7 items). Descriptive statistics, correlation analyses, and multivariable linear regression were performed.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n A total of 387 valid responses were analyzed. Respondents were recruited from 24 provincial-level administrative regions, although the sample was concentrated in Eastern China. Overall, 81.9% of nurses demonstrated good Mpox-related knowledge, and 97.4% showed positive attitudes. Knowledge scores were positively correlated with attitudes (\n p<\/jats:italic>\n \u202f&lt;\u202f0.001). Multivariable analysis revealed that professional title and receipt of Mpox-related workplace training were independently associated with higher knowledge scores (adjusted\n R<\/jats:italic>\n 2<\/jats:sup>\n \u202f=\u202f9.0%). Professional title was also a significant determinant of attitudes (adjusted\n R<\/jats:italic>\n 2<\/jats:sup>\n \u202f=\u202f3.9%).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n Chinese nurses exhibited generally high levels of knowledge and positive attitudes toward Mpox in the post-outbreak period, suggesting a high baseline awareness of EIDs. Workplace training and professional role differentiation appear central to preparedness. These findings highlight the importance of sustained, structured infectious disease education and leadership-oriented training to strengthen nursing preparedness for future EID threats.<\/jats:p>\n <\/jats:sec>","DOI":"10.3389\/fpubh.2026.1769762","type":"journal-article","created":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T06:06:32Z","timestamp":1779689192000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Preparedness of Chinese nurses for emerging infectious diseases: evidence from a nationwide online cross-sectional survey on monkeypox knowledge and attitudes"],"prefix":"10.3389","volume":"14","author":[{"given":"Yuan","family":"Gao","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Xuanwu Hospital, Capital Medical University","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fang-Yu","family":"Li","sequence":"additional","affiliation":[{"name":"Innovation Center for Neurological Disorders and Department of Neurology, Xuanwu Hospital, Capital Medical University","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan-Fang","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Gynecology, Affiliated Hospital of Shandong University of Traditional Chinese Medicine","place":["Shandong, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling-Zhi","family":"Xu","sequence":"additional","affiliation":[{"name":"Innovation Center for Neurological Disorders and Department of Neurology, Xuanwu Hospital, Capital Medical University","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,5,25]]},"reference":[{"key":"ref1","volume-title":"WHO Handbook","year":"2018"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"837","DOI":"10.1016\/j.cell.2020.10.022","article-title":"Emerging pandemic diseases: how we got to COVID-19","volume":"183","author":"Morens","year":"2020","journal-title":"Cell"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"990","DOI":"10.1038\/nature06536","article-title":"Global trends in emerging infectious diseases","volume":"451","author":"Jones","year":"2008","journal-title":"Nature"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1016\/S0140-6736(10)61458-4","article-title":"Burden of endemic health-care-associated infection in developing countries: systematic review and meta-analysis","volume":"377","author":"Allegranzi","year":"2011","journal-title":"Lancet"},{"key":"ref5","volume-title":"Guidelines on Core Components of Infection Prevention and Control Programmes: At the National and Acute Health Care Facility Level","year":"2016"},{"key":"ref6","volume-title":"Improving Infection Prevention and Control at the Health Facility: Interim Practical Manual Supporting Implementation of the WHO Guidelines on Core Components of Infection Prevention and Control Programmes","year":"2018"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1016\/S0140-6736(22)02075-X","article-title":"Monkeypox","volume":"401","author":"Mitja","year":"2023","journal-title":"Lancet"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"1783","DOI":"10.1056\/NEJMra2208860","article-title":"Monkeypox","volume":"387","author":"Gessain","year":"2022","journal-title":"N Engl J Med"},{"key":"ref9","volume-title":"2022\u201324 Mpox (Monkeypox) Outbreak: Global Trends","year":"2024"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"753","DOI":"10.3390\/v17060753","article-title":"Mpox 2022 to 2025 update: a comprehensive review on its complications, transmission","volume":"17","author":"Yadav","year":"2025","journal-title":"Diagnosis, and Treatment Viruses"},{"key":"ref11","first-page":"631","article-title":"Research advances in the scientific prevention and control of Monkeypox","volume":"39","author":"Jieying","year":"2023","journal-title":"Chinese J. 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