{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T06:05:03Z","timestamp":1789452303830,"version":"build-2803163510"},"reference-count":60,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T00:00:00Z","timestamp":1789430400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Public Health"],"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To understand the current status, categorical characteristics, and influencing factors of health literacy among family caregivers of cancer patients, providing evidence and guidance for enhancing caregivers\u2019 health literacy and caregiving capabilities to improve cancer patients\u2019 quality of life.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This study employed convenience sampling to select 287 family caregivers of cancer patients admitted to a tertiary-level Class A hospital in Weifang City between February and August 2025. A cross-sectional survey was conducted using a demographic questionnaire, the Chinese version of the Cancer Caregiver Health Literacy Scale, the General Self-Efficacy Scale, the Caregiver Sense of Efficacy Scale, and the Perceived Social Support Scale. Data analysis employed latent profile analysis of health literacy among family caregivers using Mplus 8.0 software, supplemented by descriptive analysis, univariate analysis, and multivariate logistic regression analysis via SPSS 25.0 to explore factors influencing health literacy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 271 valid questionnaires were retrieved. The mean health literacy score among family caregivers of cancer patients was 134 (120, 153), indicating a moderate level. The dimension \u201cProcessing Health Information\u201d had the lowest mean score of 12 (9, 12). The dimension \u201cUnderstanding Patient Needs and Preferences\u201d scored highest at 18 (18, 22). Based on latent profile analysis, family caregivers of cancer patients were categorized into three groups: low health literacy (49.8%), moderate health literacy (25.4%), and high health literacy (24.7%). Multivariate logistic regression analysis revealed that age (OR\u202f=\u202f9.445, 95% CI: 1.646\u201354.196), educational attainment (OR\u202f=\u202f0.50, 95% CI: 0.003\u20130.777), occupation (OR\u202f=\u202f0.116, 95% CI: 0.021\u20130.641), and other factors were significantly associated with health literacy categories among family caregivers of cancer patients (\n                      <jats:italic>p<\/jats:italic>\n                      \u202f&amp;lt;\u202f0.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The overall health literacy level among family caregivers of cancer patients was moderate, with nearly half (49.8%) falling into the low health literacy group, though significant heterogeneity existed. Caregivers\u2019 health literacy was influenced by multiple factors, including age, educational attainment, economic status, self-efficacy, social support, and caregiving experience.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fpubh.2026.1807631","type":"journal-article","created":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T05:36:00Z","timestamp":1789450560000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Latent profile analysis and influencing factors of health literacy among family caregivers of cancer patients"],"prefix":"10.3389","volume":"14","author":[{"given":"Fanjiao","family":"Meng","sequence":"first","affiliation":[{"name":"School of Nursing, Shandong Second Medical University","place":["Weifang, Shandong, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyu","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Neurology, Qingdao Women and Children\u2019s Hospital","place":["Qingdao, Shandong, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shujuan","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Neurology, Weifang People\u2019s Hospital (The First Affiliated Hospital of Shandong Second Medical University)","place":["Weifang, Shandong, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Oncology, Weifang People\u2019s Hospital (The First Affiliated Hospital of Shandong Second Medical University)","place":["Weifang, Shandong, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yihong","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Oncology, Weifang People\u2019s Hospital (The First Affiliated Hospital of Shandong Second Medical University)","place":["Weifang, Shandong, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinhong","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Oncology, Weifang People\u2019s Hospital (The First Affiliated Hospital of Shandong Second Medical University)","place":["Weifang, Shandong, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,9,15]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"229","DOI":"10.3322\/caac.21834","article-title":"Global cancer statistics 2022: Globocan estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"74","author":"Bray","year":"2024","journal-title":"CA Cancer J Clin"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"933","DOI":"10.7507\/1007-4848.202405013","article-title":"Interpretation of the key points of \"global cancer statistics 2022:Globocan estimates of incidence and mortality worldwide for 36 cancers in 185 countries\"","volume":"31","author":"Wang","year":"2024","journal-title":"Chin J Clin Thorac Cardiovasc Surg"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"393","DOI":"10.3969\/j.issn.1006-5253.2024.05.014","article-title":"Interpretation on the report of global cancer statistics 2022","volume":"31","author":"Zhang","year":"2024","journal-title":"Chin J Hosp Stat"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1093\/jnci\/djab204","article-title":"Identifying novel causes of cancers to enhance cancer prevention: new strategies are needed","volume":"114","author":"Brennan","year":"2022","journal-title":"J Natl Cancer Inst"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"28","DOI":"10.20116\/j.issn2095-0616.2025.16.05","article-title":"Research progress of demoralization syndrome in cancer patients","volume":"15","author":"Gao","year":"2025","journal-title":"China Med Pharm"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"151176","DOI":"10.1016\/j.soncn.2021.151176","article-title":"Advanced cancer as a chronic disease: introduction","volume":"37","author":"Pituskin","year":"2021","journal-title":"Semin Oncol Nurs"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"856","DOI":"10.3761\/j.issn.0254-1769.2020.06.012","article-title":"The psychological experience of caregivers of patients with advanced cancer:a meta-synthesis of qualitative studies","volume":"55","author":"Wang","year":"2020","journal-title":"Chin J Nurs"},{"key":"ref8","year":"2022"},{"key":"ref9","year":"2020"},{"key":"ref10","first-page":"161","article-title":"Systematic review of the effects of cognitive behavioral therapy on quality of life and depression of informal caregivers of patients with cancer","volume":"16","author":"Zhang","year":"2019","journal-title":"China Med Herald"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"2160","DOI":"10.1002\/cncr.28057","article-title":"Informal caregiving for cancer patients","volume":"119","author":"Romito","year":"2013","journal-title":"Cancer"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1007\/s00520-022-07468-7","article-title":"Systematic review of caregiver burden, unmet needs and quality-of-life among informal caregivers of patients with pancreatic cancer","volume":"31","author":"Chong","year":"2022","journal-title":"Support Care Cancer"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"356","DOI":"10.1016\/j.pec.2008.02.022","article-title":"Understanding the impact of family caregiver cancer literacy on patient health outcomes","volume":"71","author":"Bevan","year":"2008","journal-title":"Patient Educ Couns"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"701","DOI":"10.1016\/j.pan.2015.05.471","article-title":"Pancreatic cancer: patient and caregiver perceptions on diagnosis, psychological impact, and importance of support","volume":"15","author":"Engebretson","year":"2015","journal-title":"Pancreatology"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1002\/pon.1703","article-title":"Objective burden, resources, and other stressors among informal cancer caregivers: a hidden quality issue?","volume":"20","author":"van Ryn","year":"2011","journal-title":"Psychooncology"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"6689","DOI":"10.1007\/s00520-021-06251-4","article-title":"The psychological symptom burden in partners of pancreatic cancer patients: a population-based cohort study","volume":"29","author":"Dengs\u00f8","year":"2021","journal-title":"Support Care Cancer"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"1052","DOI":"10.1001\/jama.2014.304","article-title":"Caregiver burden: a clinical 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(HLQ)","volume":"13","author":"Osborne","year":"2013","journal-title":"BMC Public Health"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"1578","DOI":"10.1093\/heapro\/daaa157","article-title":"Health promotion glossary 2021","volume":"36","author":"Nutbeam","year":"2021","journal-title":"Health Promot Int"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1186\/1471-2458-12-80","article-title":"Health literacy and public health: a systematic review and integration of definitions and models","volume":"12","author":"S\u00f8rensen","year":"2012","journal-title":"BMC Public Health"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"4121","DOI":"10.1007\/s00520-018-4283-1","article-title":"Identification of resources and skills developed by partners of patients with advanced colon cancer: a qualitative study","volume":"26","author":"Meunier-Beillard","year":"2018","journal-title":"Support Care Cancer"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"e191","DOI":"10.1111\/hsc.12368","article-title":"Health literacy of caregivers of adult care recipients: a systematic scoping review","volume":"26","author":"Yuen","year":"2018","journal-title":"Health Soc Care Community"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"626","DOI":"10.1080\/10410236.2014.986026","article-title":"Correlates of cancer information overload: focusing on individual ability and motivation","volume":"31","author":"Chae","year":"2016","journal-title":"Health Commun"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"1501","DOI":"10.1089\/jpm.2019.0027","article-title":"A linguistic model of communication types in palliative medicine: effects of multidrug-resistant organisms colonization or infection and isolation measures in end of life on family caregivers' knowledge, attitude, and practices","volume":"22","author":"Peters","year":"2019","journal-title":"J Palliat 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scale-cancer","volume":"29","author":"Lin","year":"2023","journal-title":"Chin J Mod Nurs"},{"key":"ref32","first-page":"177","article-title":"Optimistic self-beliefs: assessment of general perceived self-efficacy in thirteen cultures","volume":"3","author":"Schwarzer","year":"1997","journal-title":"World Psychology"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"37","DOI":"10.3969\/j.issn.1006-6020.2001.01.007","article-title":"Evidences for reliability and validity of the Chinese version of general self-efficacy scale","volume":"7","author":"Wang","year":"2001","journal-title":"Chin J Appl Psychol"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1097\/00006842-198707000-00001","article-title":"Social support, type a behavior, and coronary artery disease","volume":"49","author":"Cohen","year":"1987","journal-title":"Psychosom Med"},{"key":"ref35","first-page":"41","article-title":"Perceivedsocial support scale, PSSS","volume":"10","author":"Jiang","year":"2001","journal-title":"Chin J Behav Med Sci"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1177\/0164027504264493","article-title":"Positive aspects of caregiving: contributions of the reach project to the development of new measures for Alzheimer\u2019s caregiving","volume":"26","author":"Tarlow","year":"2004","journal-title":"Res Aging"},{"key":"ref37","first-page":"1068","article-title":"Reliability and validity of Chinese version of positive aspects of caregiving","volume":"42","author":"Zhang","year":"2007","journal-title":"Chin J Nurs"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1007\/BF01246098","article-title":"An entropy criterion for assessing the number of clusters in a mixture model","volume":"13","author":"Celeux","year":"1996","journal-title":"J Classif"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"535","DOI":"10.1080\/10705510701575396","article-title":"Deciding on the number of classes in latent class analysis and growth mixture modeling: a Monte Carlo simulation study","volume":"14","author":"Nylund-Gibson","year":"2007","journal-title":"Struct Equ Model"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"879","DOI":"10.1037\/0021-9010.88.5.879","article-title":"Common method biases in behavioral research: a critical review of the literature and recommended remedies","volume":"88","author":"Podsakoff","year":"2003","journal-title":"J Appl Psychol"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"215","DOI":"10.16719\/j.cnki.1671-6981.20200130","article-title":"Statistical approaches for testing common method bias: problems and suggestions","volume":"43","author":"Tang","year":"2020","journal-title":"J Psychol Sci"},{"key":"ref42","first-page":"181","volume-title":"Advanced SPSS Statistical Analysis Tutorial","author":"Zhang","year":"2013"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"2181","DOI":"10.1002\/pon.5204","article-title":"Variation in health literacy among family caregiver communication types","volume":"28","author":"Wittenberg","year":"2019","journal-title":"Psychooncology"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"935","DOI":"10.1002\/pon.4117","article-title":"Promoting improved family caregiver health literacy: evaluation of caregiver communication resources","volume":"26","author":"Wittenberg","year":"2017","journal-title":"Psychooncology"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1011\/17.Onf.225-233","article-title":"eHealth literacy and partner involvement in treatment decision making for men with newly diagnosed localized prostate Cancer","volume":"44","author":"Song","year":"2017","journal-title":"Oncol Nurs Forum"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"1562","DOI":"10.12102\/j.issn.1009-6493.2023.09.009","article-title":"Construction of e-health literacy education index system for older people based on smart phones","volume":"37","author":"Xu","year":"2023","journal-title":"Chin Nurs Res"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1186\/s12913-019-4335-3","article-title":"Health literacy in indigenous people with chronic disease living in remote Australia","volume":"19","author":"Rheault","year":"2019","journal-title":"BMC Health Serv Res"},{"key":"ref48","author":"Li","year":"2020"},{"key":"ref49","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1188\/16.Cjon.433-436","article-title":"Applying health literacy principles: strategies and tools to develop easy-to-read patient education resources","volume":"20","author":"Foster","year":"2016","journal-title":"Clin J Oncol Nurs"},{"key":"ref50","doi-asserted-by":"publisher","first-page":"17","DOI":"10.3390\/ijerph17113848","article-title":"The urban-rural disparity in the status and risk factors of health literacy: a cross-sectional survey in Central China","volume":"17","author":"Wang","year":"2020","journal-title":"Int J Environ Res Public Health"},{"key":"ref51","first-page":"173","article-title":"Economic considerations of health literacy","volume-title":"Nurs Econ","author":"Pawlak","year":"2005"},{"key":"ref52","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1186\/s12889-019-6538-2","article-title":"Examining income-related inequality in health literacy and health-information seeking among urban population in China","volume":"19","author":"Tang","year":"2019","journal-title":"BMC Public Health"},{"key":"ref53","doi-asserted-by":"publisher","first-page":"14","DOI":"10.3390\/ijerph14060628","article-title":"Prevalence and risk factors of low health literacy: a community-based study in Shanghai, China","volume":"14","author":"Wu","year":"2017","journal-title":"Int J Environ Res Public Health"},{"key":"ref54","doi-asserted-by":"publisher","first-page":"645","DOI":"10.12102\/j.issn.1009-6493.2022.04.014","article-title":"Status quo of psychological adaptation among family caregivers of breast cancer patients and its influencing factors","volume":"36","author":"Wu","year":"2022","journal-title":"Chin Nurs Res"},{"key":"ref55","doi-asserted-by":"publisher","first-page":"18","DOI":"10.3390\/ijerph182010595","article-title":"Self-efficacy mediates acculturation and respite care knowledge of immigrant caregivers","volume":"18","author":"Kuo","year":"2021","journal-title":"Int J Environ Res Public Health"},{"key":"ref56","doi-asserted-by":"publisher","first-page":"579","DOI":"10.16168\/j.cnki.issn.1002-9982.2022.07.001","article-title":"The influence of self-efficacy on health literacy among Chinese residents","volume":"38","author":"Mai","year":"2022","journal-title":"Chin J Health Educ"},{"key":"ref57","doi-asserted-by":"publisher","first-page":"53","DOI":"10.3870\/j.issn.1001-4152.2020.02.053","article-title":"Correlation between positive feelings and health literacy among mothers of premature infants","volume":"35","author":"Wang","year":"2020","journal-title":"J Nurs Sci"},{"key":"ref58","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1186\/s12912-024-01789-0","article-title":"Filial piety and older adult caregiving among Chinese and Chinese-American families in the United States: a concept analysis","volume":"23","author":"Xiao","year":"2024","journal-title":"BMC Nurs"},{"key":"ref59","doi-asserted-by":"publisher","first-page":"2015","DOI":"10.1002\/cncr.34164","article-title":"Comparing adult-child and spousal caregiver burden and potential contributors","volume":"128","author":"Fenton","year":"2022","journal-title":"Cancer"},{"key":"ref60","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1186\/s12904-025-01788-1","article-title":"Meta-aggregation of facilitators and barriers to home-based palliative care","volume":"24","author":"Liu","year":"2025","journal-title":"BMC Palliat Care"}],"container-title":["Frontiers in Public 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