{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T05:24:41Z","timestamp":1786944281308,"version":"build-2736575974"},"reference-count":57,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T00:00:00Z","timestamp":1786924800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Public Health"],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Chronic pruritus poses a substantial burden on patients, leading to physical discomfort, emotional distress, and psychosocial dysfunction. The Scratch Intensity and Impact Scale (SIIS) is a patient-reported outcome (PRO) measure designed to assess both scratching intensity and its effects on health-related quality of life (HRQoL). However, its psychometric properties have not been validated in a Chinese population. This study aimed to culturally adapt and psychometrically validate the SIIS for Chinese patients with chronic pruritus.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      The original SIIS was translated into Chinese following a standardized forward-backward translation procedure. In a cross-sectional study, 358 adult patients with chronic pruritus were recruited from Northeast China. Construct validity was assessed by randomly splitting the sample for exploratory factor analysis (EFA;\n                      <jats:italic>n<\/jats:italic>\n                      =\u202f179) with oblique rotation and confirmatory factor analysis (CFA;\n                      <jats:italic>n<\/jats:italic>\n                      =\u202f179). Reliability was evaluated through internal consistency (Cronbach\u2019s\n                      <jats:italic>\u03b1<\/jats:italic>\n                      and McDonald\u2019s\n                      <jats:italic>\u03c9<\/jats:italic>\n                      ), split-half reliability, and two-week test\u2013retest reliability. Content validity was examined using content validity indices.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The 13-item Chinese version of the SIIS exhibited a stable two-factor structure, explaining 84.378% of the total variance. Sampling adequacy was confirmed (KMO\u202f=\u202f0.948), and Bartlett\u2019s test indicated suitability for factor analysis (\u03c7\n                      <jats:sup>2<\/jats:sup>\n                      \u202f=\u202f6798.064,\n                      <jats:italic>p<\/jats:italic>\n                      \u202f&amp;lt;\u202f0.001). CFA demonstrated acceptable model fit: chi-square degree of freedom (\n                      <jats:italic>\u03c7<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \/df)\u202f=\u202f2.094, root mean square error of approximation (RMSEA)\u202f=\u202f0.078, standardized root mean square residual (SRMR)\u202f=\u202f0.0188. Comparative Fit Index (CFI)\u202f=\u202f0.985, Tucker\u2013Lewis Index (TLI)\u202f=\u202f0.981, Normed Fit Index (NFI)\u202f=\u202f0.972, and Incremental Fit Index (IFI)\u202f=\u202f0.985. Content validity was strong, with a scale-level content validity index (S-CVI) of 0.96 and item-level indices (I-CVI) ranging from 0.83 to 1.00. The scale also showed excellent reliability, including high internal consistency (Cronbach\u2019s\n                      <jats:italic>\u03b1<\/jats:italic>\n                      \u202f=\u202f0.971, McDonald\u2019s\n                      <jats:italic>\u03c9<\/jats:italic>\n                      \u202f=\u202f0.969), split-half reliability (Spearman\u2013Brown coefficient\u202f=\u202f0.904), and strong test\u2013retest stability over 2 weeks (\n                      <jats:italic>r<\/jats:italic>\n                      \u202f=\u202f0.958).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The Chinese version of the SIIS demonstrates strong psychometric properties, confirming its reliability and validity as a PRO instrument for evaluating scratching intensity and HRQoL impact. In this population, it shows promise as a PRO instrument for adult patients with chronic pruritus due to AD or psoriasis in dermatology settings, pending further validation in broader populations.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fpubh.2026.1836131","type":"journal-article","created":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T04:35:58Z","timestamp":1786941358000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Psychometric validation of the Chinese version of the Scratch Intensity and Impact Scale (SIIS) in patients with chronic pruritus"],"prefix":"10.3389","volume":"14","author":[{"given":"Jian","family":"Sun","sequence":"first","affiliation":[{"name":"Department of Dermatology and Venereology, The First Affiliated Hospital of Jinzhou Medical University","place":["Jinzhou, Liaoning, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiru","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology, The First Affiliated Hospital of Jinzhou Medical University","place":["Jinzhou, Liaoning, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lun","family":"He","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology, The First Affiliated Hospital of Jinzhou Medical University","place":["Jinzhou, Liaoning, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xue","family":"Tian","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology, The First Affiliated Hospital of Jinzhou Medical University","place":["Jinzhou, Liaoning, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,8,17]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"317","DOI":"10.5021\/ad.25.008","article-title":"Unraveling the pathogenesis of Asian atopic dermatitis: key characteristics and insights","volume":"37","author":"Jang","year":"2025","journal-title":"Ann Dermatol"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"1541292","DOI":"10.3389\/fpubh.2025.1541292","article-title":"Analysis and contrast of psoriasis disease burden trends in China and globally from 1990 to 2021","volume":"13","author":"Yu","year":"2025","journal-title":"Front Public Health"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"1624","DOI":"10.1097\/CM9.0000000000003636","article-title":"Regional and local burden of psoriasis in China, 1990-2021: findings from the global burden of disease study 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