{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T05:55:36Z","timestamp":1781762136166,"version":"3.54.5"},"reference-count":46,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T00:00:00Z","timestamp":1781740800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Public Health"],"abstract":"\n Objective<\/jats:title>\n To examine the impact of work\u2013family conflict (WFC) on occupational fatigue among clinical nurses in China and to identify the heterogeneity of occupational fatigue using latent profile analysis (LPA).<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n A multicenter cross-sectional survey was conducted between August and September 2025, involving 332 clinical nurses from six tertiary hospitals in Sichuan Province, China. Data were collected using a general information questionnaire, the Fatigue Assessment Instrument (FAI), and the Work\u2013Family Conflict Scale (WFC). Latent profile analysis was applied to identify distinct subgroups of occupational fatigue. Univariate analyses and multinomial logistic regression were performed to explore factors associated with different fatigue profiles.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n A total of 332 valid questionnaires were included (response rate: 97.08%). The mean occupational fatigue score was 22.07 \u00b1 2.59. Three latent profiles were identified: the low-fatigue group (8.13%), moderate-fatigue group (31.02%), and high-fatigue group (60.84%). Significant differences were observed across the three groups in daily working hours, weekly working days, and levels of work\u2013family conflict (\n P<\/jats:italic>\n &lt; 0.05). Notably, work\u2013family conflict increased progressively with fatigue severity. Multinomial logistic regression analysis showed that work\u2013family conflict, daily working hours, and weekly working days were significantly associated with membership in both the moderate-fatigue group and high-fatigue group (\n P<\/jats:italic>\n &lt; 0.05).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n Occupational fatigue among clinical nurses exhibits significant heterogeneity and can be classified into three latent profiles. Work\u2013family conflict was significantly associated with occupational fatigue profiles among clinical nurses. Nursing managers may adopt a profile-based approach to identify fatigue patterns and implement targeted interventions from an individual-differences perspective to reduce occupational fatigue among nurses.<\/jats:p>\n <\/jats:sec>","DOI":"10.3389\/fpubh.2026.1848429","type":"journal-article","created":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T05:30:43Z","timestamp":1781760643000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Work\u2013family conflict and occupational fatigue among clinical nurses in China: a latent profile analysis"],"prefix":"10.3389","volume":"14","author":[{"given":"Zhi","family":"Zeng","sequence":"first","affiliation":[{"name":"Endoscopy Center, Deyang People's Hospital, Deyang","place":["Sichuan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yazhi","family":"He","sequence":"additional","affiliation":[{"name":"Endoscopy Center, Deyang People's Hospital, Deyang","place":["Sichuan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiang","family":"Liao","sequence":"additional","affiliation":[{"name":"Endoscopy Center, Deyang People's Hospital, Deyang","place":["Sichuan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sumei","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Deyang People's Hospital, Deyang","place":["Sichuan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guoqin","family":"Mao","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery II, Sichuan Cancer Hospital and Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu","place":["Sichuan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,6,18]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1016\/j.ijnurstu.2006.02.004","article-title":"Impact of job satisfaction components on intent to leave and turnover for hospital-based nurses: a review of the research literature","volume":"44","author":"Coomber","year":"2007","journal-title":"Int J Nurs Stud"},{"key":"B2","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1016\/j.ijnurstu.2016.03.012","article-title":"Nurse staffing and patient outcomes: strengths and limitations of the evidence to inform policy and practice. 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