{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T05:19:08Z","timestamp":1787548748168,"version":"build-2736575974"},"reference-count":52,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T00:00:00Z","timestamp":1787529600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Public Health"],"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>This study systematically evaluated the prevalence of oral frailty and its associated influencing factors among patients with cancer through a comprehensive systematic review and meta-analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A systematic search was conducted across nine electronic databases up to January 13, 2026, and 13 studies involving 3,524 participants were ultimately included.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The pooled analysis demonstrated that the prevalence of oral frailty in patients with cancer was 52% (95% CI: 46%\u201359%), indicating a substantial disease burden in this population. Several factors were identified as associated with oral frailty, including denture use (OR = 15.09, 95% CI: 6.78\u201333.58), poor oral health (OR = 4.70, 95% CI: 2.13\u201310.39), physical frailty (OR = 3.63, 95% CI: 2.40\u20135.50), smoking (OR = 3.53, 95% CI: 2.34\u20135.31), malnutrition (OR = 3.40, 95% CI: 2.01-5.75), xerostomia (OR = 3.46, 95% CI: 2.11\u20135.68), and radiotherapy (OR = 2.62, 95% CI: 1.67\u20134.11). Sensitivity analysis confirmed the robustness of the results, and Egger's test indicated no significant publication bias (\n                      <jats:italic>P<\/jats:italic>\n                      &amp;gt; 0.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>These findings suggest that oral frailty is relatively common among patients with cancer and is associated with several identifiable factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Systematic review registration<\/jats:title>\n                    <jats:p>\n                      <jats:ext-link>https:\/\/www.crd.york.ac.uk\/PROSPERO\/<\/jats:ext-link>\n                      , identifier: CRD420261281120.\n                    <\/jats:p>\n                  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