{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T06:25:09Z","timestamp":1787034309375,"version":"build-2736575974"},"reference-count":42,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:00:00Z","timestamp":1787011200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Public Health"],"abstract":"<jats:p>\n                    Brucellosis is a neglected bacterial zoonosis caused by\n                    <jats:italic>Brucella<\/jats:italic>\n                    spp. with worldwide distribution. Infection typically occurs through direct contact with infected animals or consumption of unpasteurized dairy products, and the global burden of brucellosis is estimated over two million cases per year. In Latin America, brucellosis remains endemic, with important public health and economic consequences. Here, we report a family cluster of brucellosis in Guayaquil, Ecuador, involving six confirmed cases, including pediatric patients. We describe the clinical and epidemiological features of this family cluster and present\n                    <jats:italic>omp28<\/jats:italic>\n                    sequencing and phylogenetic analysis of the index case, highlighting the public health significance of\n                    <jats:italic>B. abortus<\/jats:italic>\n                    transmission in an underserved urban community. The epidemiological link of this urban family cluster to unpasteurized dairy products reinforced the need of an integrated One Health surveillance and control program from brucellosis beyond rural areas.\n                  <\/jats:p>","DOI":"10.3389\/fpubh.2026.1863867","type":"journal-article","created":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T05:36:24Z","timestamp":1787031384000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["A family cluster of brucellosis in an underserved urban community in Guayaquil city, Ecuador"],"prefix":"10.3389","volume":"14","author":[{"given":"Naomi","family":"Mora Jaramillo","sequence":"first","affiliation":[{"name":"Insituto Nacional de Salud P\u00fablica e Investigaci\u00f3n","place":["Guayaquil, Ecuador"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Solon Alberto","family":"Orlando","sequence":"additional","affiliation":[{"name":"Insituto Nacional de Salud P\u00fablica e Investigaci\u00f3n","place":["Guayaquil, Ecuador"]},{"name":"Universidad Ecotec","place":["Samborond\u00f3n, Ecuador"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherin","family":"Lucin","sequence":"additional","affiliation":[{"name":"Ministerio de Salud P\u00fablica, Guayaquil","place":["Ecuador"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabiola","family":"Jimenez-Valenzuela","sequence":"additional","affiliation":[{"name":"Universidad Cat\u00f3lica Santiago de Guayaquil","place":["Guayaquil, Ecuador"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andres Esteban","family":"Barragan-Pe\u00f1a","sequence":"additional","affiliation":[{"name":"One Health Research Group, Universidad de las Am\u00e9ricas","place":["Quito, Ecuador"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angel Sebastian","family":"Rodriguez-Pazmino","sequence":"additional","affiliation":[{"name":"One Health Research Group, Universidad de las Am\u00e9ricas","place":["Quito, Ecuador"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miguel Angel","family":"Garcia-Bereguiain","sequence":"additional","affiliation":[{"name":"One Health Research Group, Universidad de las Am\u00e9ricas","place":["Quito, Ecuador"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,8,18]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/B978-0-443-16062-2.00009-5","volume-title":"Neglected Zoonoses and Antimicrobial Resistance","author":"Deka","year":"2025"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1111\/tmi.12856","article-title":"Human-to-human transmission of Brucella\u2014a systematic review","volume":"22","author":"Tuon","year":"2017","journal-title":"Trop Med Int 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An update review for the new millennium","volume":"39","author":"Bukhari","year":"2018","journal-title":"Saudi Med J"},{"key":"ref15","article-title":"Epidemiology and risk factors of childhood brucellosis in west of Iran","author":"Khazaei","year":"2016","journal-title":"J Pediatr Perspect"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"3533","DOI":"10.1007\/s11259-024-10519-5","article-title":"Molecular epidemiology of brucellosis in Asia: insights from genotyping analyses","volume":"48","author":"Ali","year":"2024","journal-title":"Vet Res Commun"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"1778","DOI":"10.14202\/vetworld.2024.1778-1788","article-title":"Molecular typing methods to characterize Brucella spp. from animals: a review","volume":"17","author":"Daugaliyeva","year":"2024","journal-title":"Vet World"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"5301","DOI":"10.2147\/IDR.S374432","article-title":"Comparison of BP26, Omp25 and Omp31 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