{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T14:07:40Z","timestamp":1788790060133,"version":"build-2803163510"},"reference-count":24,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T00:00:00Z","timestamp":1787184000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Public Health"],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>China's nationwide rollout of diagnosis-related group (DRG) bundled payment, implemented from January 2021, is one of the most consequential structural reforms to hospital reimbursement in recent decades. Total hip arthroplasty (THA)\u2014a high-volume, implant-intensive elective procedure with marked inter-institutional cost variation\u2014provides an analytically tractable context in which to evaluate whether fixed-payment incentives alter provider resource utilization while preserving clinical quality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This retrospective longitudinal study included 2,621 consecutive THA admissions at a tertiary teaching hospital in Wenzhou, Zhejiang Province, between January 2015 and April 2026 (pre-DRG:\n                      <jats:italic>n<\/jats:italic>\n                      = 1,041; post-DRG:\n                      <jats:italic>n<\/jats:italic>\n                      = 1,580). Segmented linear regression with Newey\u2013West heteroscedasticity- and autocorrelation-consistent (HAC) standard errors was applied to 136 monthly aggregated observations (72 pre-intervention; 64 post-intervention). Primary outcomes were monthly mean total hospitalization cost, drug cost, and orthopedic implantable device cost. A composite adverse discharge outcome rate (in-hospital mortality, failure to achieve clinical improvement, and unclassified discharge) was the clinical quality endpoint. Four pre-specified sensitivity analyses addressed consumer price index (CPI) inflation adjustment, COVID-19\u2013related confounding (exclusion of 2020), Prais\u2013Winsten first-order autoregressive [AR(1)] correction, and case-mix adjustment for monthly patient age and sex composition.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Mean total hospitalization cost declined from CNY 53,476 \u00b1 14,898 to CNY 37,475 \u00b1 15,273 (\u221229.9%;\n                      <jats:italic>p<\/jats:italic>\n                      &amp;lt; 0.001). Orthopedic implantable device cost fell from CNY 35,826 \u00b1 9,607 to CNY 17,727 \u00b1 10,097 (\u221250.5%;\n                      <jats:italic>p<\/jats:italic>\n                      &amp;lt; 0.001), and drug cost from CNY 6,685 \u00b1 5,058 to CNY 5,741 \u00b1 3,311 (\u221214.1%;\n                      <jats:italic>p<\/jats:italic>\n                      &amp;lt; 0.001). Interrupted time series (ITS) modeling identified strong pre-existing downward trends in both total (\u03b2\n                      <jats:sub>1<\/jats:sub>\n                      = \u221289.79 CNY\/month;\n                      <jats:italic>p<\/jats:italic>\n                      = 0.003) and device costs (\u03b2\n                      <jats:sub>1<\/jats:sub>\n                      = \u2212104.81 CNY\/month;\n                      <jats:italic>p<\/jats:italic>\n                      = 0.001) prior to DRG implementation. Post-DRG slope changes for total and device costs did not reach statistical significance (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.071 and\n                      <jats:italic>p<\/jats:italic>\n                      = 0.061, respectively). Drug cost exhibited a significant immediate level increase (\u03b2\n                      <jats:sub>2<\/jats:sub>\n                      = 3,006 CNY;\n                      <jats:italic>p<\/jats:italic>\n                      = 0.003) followed by a statistically significant sustained monthly decline (\u03b2\n                      <jats:sub>3<\/jats:sub>\n                      = \u221227.80 CNY\/month;\n                      <jats:italic>p<\/jats:italic>\n                      = 0.045). The composite adverse discharge rate did not differ significantly between periods (1.06% vs. 0.63%; \u03c7\n                      <jats:sup>2<\/jats:sup>\n                      = 0.944;\n                      <jats:italic>p<\/jats:italic>\n                      = 0.334). Sensitivity analysis excluding 2020 yielded a statistically significant post-DRG slope change for total cost (\u03b2\n                      <jats:sub>3<\/jats:sub>\n                      = \u2212146.92 CNY\/month;\n                      <jats:italic>p<\/jats:italic>\n                      = 0.047), suggesting that COVID-19\u2013related disruptions partially attenuated this effect in the primary analysis.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Following DRG implementation, total and orthopedic implantable device costs continued their pre-existing downward trajectories, with observed expenditure sustained well below the pre-intervention counterfactual. The primary ITS analysis did not identify a statistically significant DRG-specific acceleration of this decline for total or device costs, a finding that predominantly reflects the dominant contribution of antecedent volume-based procurement reform. Drug cost exhibited the most clearly DRG-attributable effect\u2014an initial transitional surge followed by sustained statistically significant decline\u2014compatible with institutional adaptation after implementation of fixed-payment incentives. No evidence of in-hospital deterioration in adverse discharge outcomes was detected; this underpowered composite endpoint did not capture post-discharge events such as 30-day readmission or surgical-site infection.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fpubh.2026.1886645","type":"journal-article","created":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T05:28:03Z","timestamp":1787203683000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Impact of diagnosis-related group\u2013based bundled payment on hospitalization costs and clinical outcomes in total hip arthroplasty: an interrupted time series analysis from Wenzhou, China"],"prefix":"10.3389","volume":"14","author":[{"given":"KeCheng","family":"Li","sequence":"first","affiliation":[{"name":"Quality Control Office, Ruian People's Hospital, Wenzhou","place":["Zhejiang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"XiaoChan","family":"Xiang","sequence":"additional","affiliation":[{"name":"Quality Control Office, Ruian People's Hospital, Wenzhou","place":["Zhejiang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiwei","family":"Zeng","sequence":"additional","affiliation":[{"name":"Quality Control Office, Ruian People's Hospital, Wenzhou","place":["Zhejiang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ge","family":"Li","sequence":"additional","affiliation":[{"name":"Quality Control Office, Ruian People's Hospital, Wenzhou","place":["Zhejiang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JianWu","family":"Shi","sequence":"additional","affiliation":[{"name":"Quality Control Office, Ruian People's Hospital, Wenzhou","place":["Zhejiang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"XiaoLi","family":"Gao","sequence":"additional","affiliation":[{"name":"Quality Control Office, Ruian People's Hospital, Wenzhou","place":["Zhejiang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"QianWen","family":"Ye","sequence":"additional","affiliation":[{"name":"Quality Control Office, Ruian People's Hospital, Wenzhou","place":["Zhejiang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,8,20]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"1204","DOI":"10.1016\/S0140-6736(20)30925-9","article-title":"Global burden of 369 diseases and injuries in 204 countries and territories, 1990\u20132019: a systematic analysis for the global burden of disease study 2019","volume":"396","year":"2020","journal-title":"Lancet."},{"key":"B2","doi-asserted-by":"publisher","first-page":"825727","DOI":"10.3389\/fpubh.2022.825727","article-title":"Cost-effectiveness of same-day discharge surgery for primary total hip arthroplasty: a pragmatic randomised controlled study","volume":"10","author":"Shi","year":"2022","journal-title":"Front Public Health."},{"key":"B3","doi-asserted-by":"publisher","first-page":"1383308","DOI":"10.3389\/fpubh.2024.1383308","article-title":"The cost of total hip arthroplasty: compare the hospitalization costs of national centralized procurement and national volume-based procurement","volume":"12","author":"Fan","year":"2024","journal-title":"Front Public Health."},{"key":"B4","doi-asserted-by":"publisher","first-page":"1120","DOI":"10.1016\/S0140-6736(10)60063-3","article-title":"Realignment of incentives for health-care providers in China","volume":"375","author":"Yip","year":"2010","journal-title":"Lancet."},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-publhealth-031816-044247","article-title":"China's health reform update","author":"Liu","year":"2017","journal-title":"Annu Rev Public Health."},{"key":"B6","unstructured":"Guiding Opinions on the Comprehensive Promotion of the DRG\/DIP Payment Reform for Medical Insurance\n          \n          2021"},{"key":"B7","doi-asserted-by":"publisher","first-page":"e073913","DOI":"10.1136\/bmjopen-2023-073913","article-title":"Differences in inpatient performance of public general hospitals following implementation of a points-counting payment based on diagnosis-related group in Wenzhou, China","volume":"14","author":"Zhu","year":"2024","journal-title":"BMJ Open."},{"key":"B8","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1186\/s12913-020-4957-5","article-title":"The effects of diagnosis-related groups payment on hospital healthcare in China: a systematic review","volume":"20","author":"Zou","year":"2020","journal-title":"BMC Health Serv Res."},{"key":"B9","doi-asserted-by":"publisher","first-page":"776","DOI":"10.1186\/s12913-019-4650-8","article-title":"Effects of a mandatory DRG payment system in South Korea: analysis of multi-year nationwide hospital claims data","volume":"19","author":"Choi","year":"2019","journal-title":"BMC Health Serv Res."},{"key":"B10","doi-asserted-by":"publisher","first-page":"956","DOI":"10.1002\/hec.4479","article-title":"The long-run effects of diagnosis related group payment on hospital lengths of stay in a publicly funded health care system: evidence from 15 years of micro data","volume":"31","author":"Aragon","year":"2022","journal-title":"Health Econ."},{"key":"B11","doi-asserted-by":"publisher","first-page":"348","DOI":"10.1093\/ije\/dyw098","article-title":"Interrupted time series regression for the evaluation of public health interventions: a tutorial","volume":"46","author":"Lopez Bernal","year":"2017","journal-title":"Int J Epidemiol."},{"key":"B12","doi-asserted-by":"publisher","first-page":"2082","DOI":"10.1093\/ije\/dyy135","article-title":"The use of controls in interrupted time series studies of public health interventions","volume":"47","author":"Lopez Bernal","year":"2018","journal-title":"Int J Epidemiol."},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1136\/bmjgh-2022-011535","article-title":"Improving access to medicines and beyond: the national volume-based procurement policy in China","author":"Zhu","year":"2023","journal-title":"BMJ Glob Health."},{"key":"B14","unstructured":"Guiding opinions on the centralized volume-based procurement and use of high-value medical consumables organized by the state\n          \n          2021"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.2307\/1913610","article-title":"A simple, positive semi-definite, heteroskedasticity and autocorrelation consistent covariance matrix","author":"Newey","year":"1987"},{"key":"B16","doi-asserted-by":"publisher","first-page":"1563204","DOI":"10.3389\/fpubh.2025.1563204","article-title":"The impact of DRG payment reform on inpatient costs for different surgery types: an empirical analysis based on Chinese tertiary hospitals","volume":"13","author":"Ma","year":"2025","journal-title":"Front Public Health."},{"key":"B17","doi-asserted-by":"publisher","first-page":"537","DOI":"10.1016\/S0167-6296(97)00042-8","article-title":"Creaming, skimping and dumping: provider competition on the intensive and extensive margins","volume":"17","author":"Ellis","year":"1998","journal-title":"J Health Econ."},{"key":"B18","doi-asserted-by":"publisher","first-page":"519","DOI":"10.1093\/heapol\/czae022","article-title":"Hospital response to a new case-based payment system in China: the patient selection effect","volume":"39","author":"Zhang","year":"2024","journal-title":"Health Policy Plan."},{"key":"B19","doi-asserted-by":"publisher","first-page":"252","DOI":"10.1056\/NEJMsa1809010","article-title":"Two-year evaluation of mandatory bundled payments for joint replacement","volume":"380","author":"Barnett","year":"2019","journal-title":"New England Journal of Medicine."},{"key":"B20","doi-asserted-by":"publisher","first-page":"214","DOI":"10.1001\/jamainternmed.2016.8263","article-title":"Cost of joint replacement using bundled payment models","volume":"177","author":"Navathe","year":"2017","journal-title":"JAMA Intern Med."},{"key":"B21","doi-asserted-by":"publisher","first-page":"e0319582","DOI":"10.1371\/journal.pone.0319582","article-title":"The spillover effects of medicare's comprehensive care for joint replacement (cjr) model in California","volume":"20","author":"Kim","year":"2025","journal-title":"PLoS ONE."},{"key":"B22","doi-asserted-by":"publisher","first-page":"2548","DOI":"10.1007\/s00167-013-2374-6","article-title":"Knee replacement and diagnosis-related groups (DRGs): patient classification and hospital reimbursement in 11 European countries","volume":"21","author":"Tan","year":"2013","journal-title":"KSSTA."},{"key":"B23","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1186\/s12913-026-14173-2","article-title":"Impact of centralized volume-based procurement of high-value medical consumables on patients' hospitalization expenses in gansu, china: an interrupted time series analysis","volume":"26","author":"Zhang","year":"2026","journal-title":"BMC Health Serv Res."},{"key":"B24","doi-asserted-by":"publisher","first-page":"1715856","DOI":"10.3389\/fpubh.2025.1715856","article-title":"Impact of zero-markup consumable policy and national procurement of orthopedic spinal devices in china: a mixed-methods study","volume":"13","author":"Wu","year":"2026","journal-title":"Front Public Health."}],"updated-by":[{"DOI":"10.3389\/fpubh.2026.1986707","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T00:00:00Z","timestamp":1788739200000}}],"container-title":["Frontiers in Public Health"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fpubh.2026.1886645\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T13:09:13Z","timestamp":1788786553000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fpubh.2026.1886645\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,20]]},"references-count":24,"alternative-id":["10.3389\/fpubh.2026.1886645"],"URL":"https:\/\/doi.org\/10.3389\/fpubh.2026.1886645","relation":{},"ISSN":["2296-2565"],"issn-type":[{"value":"2296-2565","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,20]]},"article-number":"1886645"}}