{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T15:36:14Z","timestamp":1785771374185,"version":"3.56.0"},"reference-count":50,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T00:00:00Z","timestamp":1785715200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Qingdao Medical and Health Research Program","award":["2024-WJKY171"],"award-info":[{"award-number":["2024-WJKY171"]}]},{"name":"Medical Management Research Center of the Shandong Provincial Health Commission","award":["SDWJYJ2025CA001"],"award-info":[{"award-number":["SDWJYJ2025CA001"]}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Public Health"],"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To investigate the current status of early delayed neurocognitive recovery (dNCR) in older adult patients after major orthopedic surgery in China and analyze its influencing factors, providing a reference for early intervention by clinical workers.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Observational cohort study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A convenience sampling method was used to select patients aged 60\u202fyears or older who underwent major orthopedic surgery under general anesthesia at a tertiary hospital in Qingdao, Shandong Province, from September 2025 to June 2026. A general information questionnaire, depression scale, frailty scale, nutrition scale, and sleep quality scale were used to collect data 1\u202fday before surgery. The Beijing version of the Montreal Cognitive Assessment (MoCA) was administered 1\u202fday before surgery and on postoperative day 7 or before discharge (whichever occurred first). Variables with\n                      <jats:italic>p<\/jats:italic>\n                      \u202f&amp;lt;\u202f0.2 in the univariate analysis were entered into the binary logistic regression model to identify factors influencing dNCR.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 505 patients were included, of whom 155 (30.69%) developed dNCR. Regression analysis showed that age, sleep disorder, anesthesia time, and stroke history were independent risk factors for postoperative dNCR, and the MoCA score was a protective factor (\n                      <jats:italic>p<\/jats:italic>\n                      \u202f&amp;lt;\u202f0.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>After major orthopedic surgery, dNCR is relatively common in older adult patients. Clinical workers should strengthen early preoperative screening, identify high-risk patients, and provide targeted interventions and cognitive training, so as to improve patient outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fpubh.2026.1887947","type":"journal-article","created":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T14:43:21Z","timestamp":1785768201000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Current status and influencing factors of early delayed neurocognitive recovery in older adult patients after major orthopedic surgery under general anesthesia: a cohort study"],"prefix":"10.3389","volume":"14","author":[{"given":"Siyu","family":"Yan","sequence":"first","affiliation":[{"name":"School of Nursing, Qingdao University","place":["Qingdao, China"]},{"name":"Department of Nursing, Affiliated Hospital of Qingdao University","place":["Qingdao, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Spine Surgery, Affiliated Hospital of Qingdao University","place":["Qingdao, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yinghao","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Nursing, Affiliated Hospital of Qingdao University","place":["Qingdao, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Hospital Infection Control, Affiliated Hospital of Qingdao University","place":["Qingdao, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaolin","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Affiliated Hospital of Qingdao University","place":["Qingdao, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiamin","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Nursing, Affiliated Hospital of Qingdao University","place":["Qingdao, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Nursing, Affiliated Hospital of Qingdao University","place":["Qingdao, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,8,3]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"65","DOI":"10.3760\/cma.j.issn.0253-2352.2016.02.001","article-title":"Guidelines for the prevention of venous thromboembolism in major orthopaedic surgery in China","volume":"36","year":"2016","journal-title":"Chin J Orthop"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1016\/j.joca.2021.05.007","article-title":"The 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