{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T06:27:49Z","timestamp":1786429669870,"version":"build-2736575974"},"reference-count":50,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T00:00:00Z","timestamp":1786406400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Public Health"],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      PM\n                      <jats:sub>2.5<\/jats:sub>\n                      has been increasingly linked to digestive morbidity, but evidence on its short-term association with gastric mucosal injury remains limited. Few epidemiological studies have examined component-specific associations of PM\n                      <jats:sub>2.5<\/jats:sub>\n                      with endoscopically identified erosive gastric mucosal lesions (EGML), common indicators of impaired mucosal defense.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      We consecutively enrolled individuals undergoing gastroscopy at Yixing People\u2019s Hospital from January 1, 2024 to December 31, 2025, and collected their basic characteristics and gastroscopic findings. Daily grid concentrations of PM\n                      <jats:sub>2.5<\/jats:sub>\n                      and its five chemical components were also extracted. We applied generalized additive models to explore the lag-specific correlations between particulate pollutants and endoscopically identified EGML. Attributable burden analysis was further performed to estimate the preventable number of cases under hypothetical reduction scenarios, and the relative contribution of each component was quantified.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 60,789 individuals received gastroscopy, of whom 14,325 had EGML. A per interquartile range increase in PM\n                      <jats:sub>2.5<\/jats:sub>\n                      concentration was associated with a 7.6% higher risk of EGML [incidence rate ratio (IRR): 1.076; 95% confidence interval (CI): 1.024, 1.132]. Among PM\n                      <jats:sub>2.5<\/jats:sub>\n                      components, positive associations that remained significant after FDR correction were observed for sulfate (IRR: 1.070; 95% CI: 1.024, 1.118) and ammonium (IRR: 1.082; 95% CI: 1.026, 1.141). In contrast, no significant associations were found for nitrate (IRR: 1.012; 95% CI: 0.979, 1.046), organic matter (IRR: 1.012; 95% CI: 0.981, 1.043), and black carbon (IRR: 1.012; 95% CI: 0.982, 1.043).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      Short-term PM\n                      <jats:sub>2.5<\/jats:sub>\n                      exposure is positively associated with EGML risk. Among the five components, sulfate and ammonium showed the strongest evidence of positive associations, although their independent contributions require further study. These findings extend existing epidemiological evidence on PM\n                      <jats:sub>2.5<\/jats:sub>\n                      and gastric damage, and provide component-specific information that may inform targeted air quality management and population-level prevention of gastric mucosal diseases.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fpubh.2026.1891236","type":"journal-article","created":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T05:35:28Z","timestamp":1786426528000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Component-specific effects of PM2.5 on endoscopically identified erosive gastric mucosal lesions: a time-series study in Yixing, China"],"prefix":"10.3389","volume":"14","author":[{"given":"Xuhua","family":"Mao","sequence":"first","affiliation":[{"name":"Department of Clinical Laboratory, Innovation and Technology Transfer Center, Affiliated to Jiangsu University","place":["Yixing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yufei","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory, Precision Medicine Center, Affiliated to Jiangsu University","place":["Yixing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaohong","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Health Management Center, Yixing People\u2019s Hospital, Affiliated to Jiangsu University","place":["Yixing, China"]},{"name":"Department of General Surgery, Yixing People\u2019s Hospital, Affiliated to Jiangsu University","place":["Yixing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Health Management Center, Yixing People\u2019s Hospital, Affiliated to Jiangsu University","place":["Yixing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Han","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Xuzhou Central Hospital, Southeast University","place":["Xuzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,8,11]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"519","DOI":"10.5009\/gnl240390","article-title":"Evaluation of the efficacy and safety of a dual delayed-release formulation of 10-mg esomeprazole in patients with gastric erosions: a multicenter, randomized, double-blind, active-control, phase III study","volume":"19","author":"Lim","year":"2025","journal-title":"Gut Liver"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"772","DOI":"10.1016\/j.ejim.2014.08.010","article-title":"Prevalence of lesions detected at upper endoscopy: an Italian 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