{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T12:12:54Z","timestamp":1789042374436,"version":"build-2803163510"},"reference-count":82,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T00:00:00Z","timestamp":1788998400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Public Health"],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Short-term ambient air pollution is a known trigger for acute cardiovascular and respiratory events. Biochemical markers help reveal pollution-induced physiological changes during emergency presentations, though evidence remains fragmented.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>This scoping review mapped existing literature on short-term biochemical responses to air pollution in patients presenting acutely with cardiorespiratory conditions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Eligibility criteria<\/jats:title>\n                    <jats:p>Eligible studies were human studies assessing at least one biochemical marker in people presenting to emergency departments after short-term exposure to outdoor air pollution.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Sources of evidence<\/jats:title>\n                    <jats:p>Five databases (PubMed, Scopus, Web of Science, Embase, CINAHL) were searched from 2000 to 2025.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Charting methods<\/jats:title>\n                    <jats:p>Data were extracted using the PCC framework and summarized in structured tables.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Twelve studies met criteria. PM\n                      <jats:sub>2.5<\/jats:sub>\n                      , PM10, and NO\n                      <jats:sub>2<\/jats:sub>\n                      were most frequently linked to inflammatory and coagulative markers such as CRP, IL-6, D-dimer, and troponins, often with effects seen within hours to days.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The mapped evidence suggests that short-term air pollution exposure is associated with acute biochemical alterations. Standardized exposure windows, harmonized biomarker panels, and more detailed subgroup analyses are needed before these markers can support emergency-care pathways and environmental health policy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fpubh.2026.1892038","type":"journal-article","created":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T11:42:11Z","timestamp":1789040531000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Tracking biochemical indicators of air pollution exposure in acute cardiorespiratory emergencies: a scoping review"],"prefix":"10.3389","volume":"14","author":[{"given":"Davide","family":"Campagna","sequence":"first","affiliation":[{"name":"Department of Clinical and Experimental Medicine, School of Medicine, University of Catania","place":["Catania, Italy"]},{"name":"Emergency Department-\u201cPoliclinico-San Marco\u201d Teaching Hospital of Catania","place":["Catania, 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