{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T11:09:53Z","timestamp":1788952193992,"version":"build-2803163510"},"reference-count":40,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T00:00:00Z","timestamp":1788912000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Public Health"],"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study aimed to evaluate the effectiveness of an intervention based on the behavior change wheel (BCW) in improving health promotion behaviors, self-efficacy, and pregnancy rates among women with polycystic ovary syndrome (PCOS) experiencing infertility.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This randomized controlled trial included 66 PCOS patients with infertility recruited from the gynecology outpatient department of a tertiary hospital in Hangzhou, China. Participants were randomly assigned to either the experimental group (\n                      <jats:italic>n<\/jats:italic>\n                      \u202f=\u202f33), which received a 12-week health promotion behavior intervention based on the BCW, or the control group (\n                      <jats:italic>n<\/jats:italic>\n                      \u202f=\u202f33), which received usual care. Outcomes were measured at baseline and immediately after the intervention.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 62 participants were included in the full analysis set, and 56 in the per-protocol set. Health promotion behaviors improved significantly from pre-intervention to post-intervention in both groups (\n                      <jats:italic>p<\/jats:italic>\n                      \u202f&amp;lt;\u202f0.05). At post-intervention, the experimental group showed significantly greater improvement compared to the control group (\n                      <jats:italic>p<\/jats:italic>\n                      \u202f&amp;lt;\u202f0.05). Self-efficacy was also significantly higher in the experimental group than in the control group at post-intervention (\n                      <jats:italic>p<\/jats:italic>\n                      \u202f&amp;lt;\u202f0.05). However, the difference in pregnancy rate between the two groups was not statistically significant (\n                      <jats:italic>p<\/jats:italic>\n                      \u202f&amp;gt;\u202f0.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The BCW-based intervention program showed promise in improving health promotion behaviors and self-efficacy among PCOS patients with infertility over 12\u202fweeks, although its effect on pregnancy rate was not statistically significant. Longer-term studies are warranted to evaluate sustained benefits and reproductive outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical trial registration<\/jats:title>\n                    <jats:p>\n                      <jats:ext-link>https:\/\/www.chictr.org.cn<\/jats:ext-link>\n                      , identifier (ChiCTR2500103129).\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fpubh.2026.1904708","type":"journal-article","created":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T10:14:11Z","timestamp":1788948851000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["A health promotion behavior intervention for women with polycystic ovary syndrome experiencing infertility: a randomized controlled trial"],"prefix":"10.3389","volume":"14","author":[{"given":"Pingpei","family":"Dong","sequence":"first","affiliation":[{"name":"Department of Gynecology and Obstetrics, Hangzhou Hospital of Traditional Chinese Medicine, Affiliated Hangzhou Traditional Chinese Medicine (TCM) Hospital of Zhejiang Chinese Medical University","place":["Hangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongjie","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, Hangzhou Hospital of Traditional Chinese Medicine, Affiliated Hangzhou Traditional Chinese Medicine (TCM) Hospital of Zhejiang Chinese Medical University","place":["Hangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, Hangzhou Hospital of Traditional Chinese Medicine, Affiliated Hangzhou Traditional Chinese Medicine (TCM) Hospital of Zhejiang Chinese Medical University","place":["Hangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunxi","family":"Xue","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, Hangzhou Hospital of Traditional Chinese Medicine, Affiliated Hangzhou Traditional Chinese Medicine (TCM) Hospital of Zhejiang Chinese Medical University","place":["Hangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xunxun","family":"Ying","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, Hangzhou Hospital of Traditional Chinese Medicine, Affiliated Hangzhou Traditional Chinese Medicine (TCM) Hospital of Zhejiang Chinese Medical University","place":["Hangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Jin","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, Hangzhou Hospital of Traditional Chinese Medicine, Affiliated Hangzhou Traditional Chinese Medicine (TCM) Hospital of Zhejiang Chinese Medical University","place":["Hangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,9,9]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1186\/1741-7015-8-41","article-title":"Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan","volume":"8","author":"Teede","year":"2010","journal-title":"BMC Med"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"16057","DOI":"10.1038\/nrdp.2016.57","article-title":"Polycystic ovary syndrome","volume":"2","author":"Azziz","year":"2016","journal-title":"Nat Rev Dis Primers"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1007\/978-3-319-99817-6_39","volume-title":"Advanced Practice in Endocrinology 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