{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T06:07:34Z","timestamp":1788847654623,"version":"build-2803163510"},"reference-count":19,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T00:00:00Z","timestamp":1788825600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Public Health"],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Large language models (LLMs) are reshaping medical education.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To examine whether learning approach\u2014AI-assisted, textbook-based, or blended\u2014was associated with diagnostic accuracy for acute abdominal conditions among emergency interns.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      We reviewed 720 clinical decisions by 72 emergency interns at a tertiary center over 12\u202fmonths. Interns were classified into three groups: textbook-based (\n                      <jats:italic>n<\/jats:italic>\n                      =\u202f27), AI-assisted (\n                      <jats:italic>n<\/jats:italic>\n                      =\u202f21), and blended (\n                      <jats:italic>n<\/jats:italic>\n                      =\u202f24). Propensity score matching with pair-stratified GEE addressed selection bias and clustering.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Diagnostic accuracy was 73.0% (textbook), 82.4% (AI-assisted), and 87.1% (blended) (\n                      <jats:italic>p<\/jats:italic>\n                      &amp;lt;\u202f0.001). Blended learning showed the largest advantage over textbook (adjusted OR\u202f=\u202f3.21, 95% CI: 1.87\u20135.51,\n                      <jats:italic>p<\/jats:italic>\n                      &amp;lt;\u202f0.001), followed by AI-assisted (adjusted OR\u202f=\u202f1.68, 95% CI: 0.99\u20132.85,\n                      <jats:italic>p<\/jats:italic>\n                      =\u202f0.053). Matched analyses confirmed the benefit for blended learning (\n                      <jats:italic>p<\/jats:italic>\n                      =\u202f0.011). Subgroup analyses suggested larger effects for severe cases (OR\u202f=\u202f4.92) and atypical presentations (OR\u202f=\u202f3.85), with an E-value of 5.88 supporting robustness against unmeasured confounding.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Blended learning combining AI tools with traditional resources showed the strongest association with diagnostic accuracy, suggesting that integrated rather than exclusive approaches may better support clinical reasoning in emergency training.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fpubh.2026.1914097","type":"journal-article","created":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T05:34:06Z","timestamp":1788845646000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["AI-assisted vs. textbook-based vs. blended learning for acute abdomen diagnosis: a retrospective cohort study of emergency interns"],"prefix":"10.3389","volume":"14","author":[{"given":"Weidi","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Trauma Center and Emergency Surgery, First Affiliated Hospital of Fujian Medical University","place":["Fuzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhipeng","family":"Fang","sequence":"additional","affiliation":[{"name":"Department of Trauma Center and Emergency Surgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University","place":["Fuzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,9,8]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1186\/1749-799X-8-3","article-title":"WSES guidelines for management of intra-abdominal infections","volume":"8","author":"Sartelli","year":"2013","journal-title":"World J Emerg Surg"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"1923","DOI":"10.1016\/S0140-6736(10)61654-5","article-title":"Health professionals for a new century: transforming education to strengthen health systems in an interdependent world","volume":"376","author":"Frenk","year":"2010","journal-title":"Lancet"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"103537","DOI":"10.1016\/j.nepr.2022.103537","article-title":"Open artificial intelligence platforms in nursing education: tools for academic progress or abuse","volume":"66","author":"O'Connor","year":"2023","journal-title":"Nurse Educ Pract"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"915","DOI":"10.3390\/healthcare11060915","article-title":"ChatGPT utility in healthcare education, research, and practice: systematic review on the promising perspectives and valid concerns","volume":"11","author":"Sallam","year":"2023","journal-title":"Healthcare (Basel)"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"e68070","DOI":"10.2196\/68070","article-title":"Evaluating the potential and accuracy of ChatGPT-3.5 and 4.0 in medical licensing and in-training examinations: systematic review and meta-analysis","volume":"11","author":"Jaleel","year":"2025","journal-title":"JMIR Med Educ"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1186\/s13017-026-00674-2","article-title":"Artificial intelligence in emergency surgery: a scoping review within the ARIES project","volume":"21","author":"Simone","year":"2026","journal-title":"World J Emerg Surg"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"112000","DOI":"10.3748\/wjg.v31.i43.112000","article-title":"Artificial intelligence in acute appendicitis: a comprehensive review of machine learning and deep learning applications","volume":"31","author":"Akbulut","year":"2025","journal-title":"World J Gastroenterol"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1177\/016146811311500307","article-title":"The effectiveness of online and blended learning: a meta-analysis of the empirical literature","volume":"115","author":"Means","year":"2009","journal-title":"Teach Coll Rec"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"775","DOI":"10.1097\/00001888-200308000-00003","article-title":"The importance of cognitive errors in diagnosis and strategies to minimize them","volume":"78","author":"Croskerry","year":"2003","journal-title":"Acad Med"},{"key":"ref10","author":"Wang","year":"2026"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.18637\/jss.v042.i08","article-title":"MatchIt: nonparametric preprocessing for parametric causal inference","volume":"42","author":"Ho","year":"2011","journal-title":"J Stat Softw"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"268","DOI":"10.7326\/M16-2607","article-title":"Sensitivity analysis in observational research: introducing the E-value","volume":"167","author":"VanderWeele","year":"2017","journal-title":"Ann Intern Med"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1111\/j.2517-6161.1995.tb02031.x","article-title":"Controlling the false discovery rate: a practical and powerful approach to multiple testing","volume":"57","author":"Benjamini","year":"1995","journal-title":"J R Stat Soc Ser B Stat Methodol"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"e0252474","DOI":"10.1371\/journal.pone.0252461","article-title":"Effectiveness of blended learning in pharmacy education: a systematic review and meta-analysis","volume":"16","author":"Balakrishnan","year":"2021","journal-title":"PLoS One"},{"key":"ref15","author":"Ouyang","year":"2026"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"arXiv:2506.14774","DOI":"10.48550\/arXiv.2506.14774","article-title":"MedSyn: enhancing diagnostics with human-AI collaboration","author":"Sayin","year":"2025","journal-title":"arXiv"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"1292","DOI":"10.1038\/s41586-026-10764-5","article-title":"Towards conversational AI for disease management","volume":"655","author":"Li\u00e9vin","year":"2026","journal-title":"Nature"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"e210280","DOI":"10.48550\/arXiv.2108.07258","article-title":"On the opportunities and risks of foundation models","volume":"4","year":"2022","journal-title":"Radiol Artif Intell"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1037\/0003-066X.55.1.68","article-title":"Self-determination theory and the facilitation of intrinsic motivation, social development, and well-being","volume":"55","author":"Ryan","year":"2000","journal-title":"Am Psychol"}],"container-title":["Frontiers in Public Health"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fpubh.2026.1914097\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T05:34:07Z","timestamp":1788845647000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fpubh.2026.1914097\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,8]]},"references-count":19,"alternative-id":["10.3389\/fpubh.2026.1914097"],"URL":"https:\/\/doi.org\/10.3389\/fpubh.2026.1914097","relation":{},"ISSN":["2296-2565"],"issn-type":[{"value":"2296-2565","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,8]]},"article-number":"1914097"}}