{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T05:30:08Z","timestamp":1765776608102,"version":"3.48.0"},"reference-count":12,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T00:00:00Z","timestamp":1765756800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Radiol."],"abstract":"\n Objective<\/jats:title>\n To evaluate the efficacy of flow diverter implantation for treating CTA-negative giant vertebral artery dissection aneurysm (VADA) and to address the challenges in lesion characterization using MRI.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n A 66-year-old male patient presented with a 3-month history of left facial numbness and dysarthria. Initial MRI-T1 revealed a mixed signal intensity lesion in the CPA region. However, both CTA and digital subtraction angiography (DSA) failed to identify any significant vascular abnormalities. Subsequently, CT-perfusion and dynamic contrast-enhanced computed tomography (DCE-CT) were performed to further characterize the lesion.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n DCE-CT revealed a giant VADA, which was significantly larger than the lesion initially detected by MRI and was identified as the cause of hypoperfusion in the posterior circulation. Based on these findings, a flow diverter implantation procedure was performed successfully without complications. Angiographic follow-up at 8 months demonstrated no recurrence of the lesion. At the 14-month clinical follow-up, the patient exhibited complete resolution of symptoms, with a mRS score of 0, indicating an excellent functional outcome.<\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n Flow diverter implantation may be an effective treatment for CTA-negative giant VADAs. The limitations of MRI in accurately characterizing lesion size underscore the necessity of advanced imaging techniques, such as DCE-CT, for precise device selection and deployment.<\/jats:p>\n <\/jats:sec>","DOI":"10.3389\/fradi.2025.1625207","type":"journal-article","created":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T05:25:34Z","timestamp":1765776334000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Flow diverter implantation for CTA-negative giant vertebral artery dissection aneurysm: a case report"],"prefix":"10.3389","volume":"5","author":[{"given":"Jun-Ting","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian-Min","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kai-Jun","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2025,12,15]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"1008","DOI":"10.1136\/neurintsurg-2021-017619","article-title":"Predictors of unfavorable outcome in stent-assisted coiling for symptomatic unruptured intracranial spontaneous vertebral artery dissecting aneurysms (uis-VADAs): results from a multicenter study","volume":"14","author":"Zhao","year":"2021","journal-title":"J Neurointerv 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