{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T18:41:06Z","timestamp":1773859266823,"version":"3.50.1"},"reference-count":33,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T00:00:00Z","timestamp":1767744000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Aging"],"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Muscle health, including muscle volume, is an independent risk factor for physical disability and metabolic disorders. Although low muscle mass has been associated with hearing loss, the association between computed tomography (CT)-derived muscle quality and hearing has not been explored.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This cross-sectional study examined associations between abdominal body composition and hearing thresholds in 7,774 adults (4,537 men and 3,237 women) aged \u226540\u00a0years undergoing routine health check-ups. Abdominopelvic CT and pure-tone audiometry were performed, and total abdominal muscle area (TAMA), normal-attenuation muscle area (NAMA), low-attenuation muscle area (LAMA), intermuscular adipose tissue (IMAT), visceral fat area (VFA), and subcutaneous fat area (SFA) were quantified from CT-based muscle quality maps. The best-ear pure-tone average (PTA, 1\u20134\u00a0kHz) was analyzed as the log\n                      <jats:sub>e<\/jats:sub>\n                      -transformed PTA. Multivariable linear regression models were fitted separately for men and women, adjusting for age, cardiovascular risk factors, and lifestyle variables.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The log\n                      <jats:sub>e<\/jats:sub>\n                      -transformed LAMA index was independently associated with hearing in both sexes. Each 10% increase in the log\n                      <jats:sub>e<\/jats:sub>\n                      -transformed LAMA index corresponded to an estimated 0.11\u00a0dB worsening of PTA in men and 0.14\u00a0dB worsening in women. In women, TAMA, NAMA, and VFA indices were associated with PTA; these associations were confined to women in their 50s and 60s in decade-stratified analyses. No abdominal body composition indices were significantly associated with hearing thresholds in any age group among men.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>These findings suggest that abdominal body composition is associated with age-related hearing loss (ARHL), particularly in midlife women, and highlight skeletal muscle health as a potential target for hearing preservation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fragi.2025.1706350","type":"journal-article","created":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T06:51:57Z","timestamp":1767768717000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Muscle quality correlates with hearing thresholds: a cross-sectional analysis"],"prefix":"10.3389","volume":"6","author":[{"given":"Young-Jee","family":"Jeon","sequence":"first","affiliation":[{"name":"Department of Family Medicine, Ulsan University Hospital, University of Ulsan College of Medicine","place":["Ulsan, Republic of Korea"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ji Ho","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Occupational and Environmental Medicine, Ulsan University Hospital, University of Ulsan College of Medicine","place":["Ulsan, Republic of Korea"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Byung Chul","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Ulsan University Hospital, University of Ulsan College of Medicine","place":["Ulsan, Republic of Korea"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joong Keun","family":"Kwon","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Ulsan University Hospital, University of Ulsan College of Medicine","place":["Ulsan, Republic of Korea"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2026,1,7]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"3394","DOI":"10.1210\/jc.2018-00554","article-title":"Ectopic lipid deposition is associated with insulin resistance in postmenopausal women","volume":"103","author":"Abildgaard","year":"2018","journal-title":"J. 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