{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T06:08:22Z","timestamp":1788761302104,"version":"build-2803163510"},"reference-count":85,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T00:00:00Z","timestamp":1788739200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["P01-AG020166"],"award-info":[{"award-number":["P01-AG020166"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["U19-AG051426"],"award-info":[{"award-number":["U19-AG051426"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Aging"],"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Being married is related to better health, but many studies reveal greater health benefits among men relative to women. Some research has indicated that married individuals exhibit decelerated epigenetic age relative to individuals who are not married, but questions remain regarding gender differences therein. The purpose was to investigate gender differences in associations of marital status to epigenetic age (ing) assessed on three clocks\/algorithms (PhenoAge, GrimAge, and DunedinPACE).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Data from 762 participants in the national Midlife in the United States Study (MIDUS II; men\n                      <jats:italic>N<\/jats:italic>\n                      = 382, women\n                      <jats:italic>N<\/jats:italic>\n                      = 380) were used. Weighted linear regressions were conducted to test the hypotheses that 1) being married would be associated with decelerated epigenetic age (ing) and that 2) this association would be stronger among men than women.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Being married, relative to being separated or divorced, was associated with decelerated epigenetic aging on DunedinPACE, although not PhenoAge or GrimAge. Investigating gender differences revealed a divergence regarding never marrying, a marital status that accelerated GrimAge and DunedinPACE scores among men, but not women.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>These results contribute new knowledge about marital status and early risk for disease, as indicated by accelerated pace of aging among men and women whose relationships dissolved. More research is needed to identify factors explaining why men who never marry may be at risk for accelerated epigenetic aging while women are not.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fragi.2026.1931190","type":"journal-article","created":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T05:34:38Z","timestamp":1788759278000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Gender differences in the association between marriage and epigenetic age"],"prefix":"10.3389","volume":"7","author":[{"given":"Theo O.","family":"Moran","sequence":"first","affiliation":[{"name":"Psychology Department, Crean College of Health and Behavioral Sciences, Chapman University","place":["Orange, CA, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alina M.","family":"Kushner","sequence":"additional","affiliation":[{"name":"Psychology Department, Crean College of Health and Behavioral Sciences, Chapman University","place":["Orange, CA, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theodore F.","family":"Robles","sequence":"additional","affiliation":[{"name":"Department of Psychology, University of California","place":["Los Angeles, CA, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer W.","family":"Robinette","sequence":"additional","affiliation":[{"name":"Psychology Department, Crean College of Health and Behavioral Sciences, Chapman University","place":["Orange, CA, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,9,7]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"3869","DOI":"10.1200\/JCO.2013.49.6489","article-title":"Marital status and survival in patients with cancer","volume":"31","author":"Aizer","year":"2013","journal-title":"J. Clin. Oncol."},{"key":"B2","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1177\/2054270419888916","article-title":"Being married increases life expectancy of white but not black Americans","volume":"13","author":"Assari","year":"2019","journal-title":"J. Family and Reproductive Health"},{"key":"B3","doi-asserted-by":"publisher","first-page":"e73420","DOI":"10.7554\/eLife.73420","article-title":"DunedinPACE, a DNA methylation biomarker of the pace of aging","volume":"11","author":"Belsky","year":"2022","journal-title":"eLife"},{"key":"B4","doi-asserted-by":"publisher","first-page":"gbaf255","DOI":"10.1093\/geronb\/gbaf255","article-title":"Grandparent caregiving and epigenetic aging among midlife and older adults in the United States. Journals of gerontology","volume":"81","author":"Bhat","year":"2026","journal-title":"Ser. B, Psychol. Sci. Soc. Sci."},{"key":"B5","doi-asserted-by":"publisher","first-page":"1193","DOI":"10.1126\/science.aab3389","article-title":"Human telomere biology: a contributory and interactive factor in aging, disease risks, and protection","volume":"350","author":"Blackburn","year":"2015","journal-title":"Science"},{"key":"B6","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1016\/j.ypmed.2016.06.019","article-title":"Increased risk of death immediately after losing a spouse: cause-specific mortality following widowhood in Norway","volume":"89","author":"Brenn","year":"2016","journal-title":"Prev. Med."},{"key":"B7","doi-asserted-by":"publisher","first-page":"1151","DOI":"10.1037\/hea0001524","article-title":"Cumulative stress and epigenetic aging: examining the role of psychological moderators","volume":"44","author":"Cha","year":"2025","journal-title":"Health Psychol."},{"key":"B8","doi-asserted-by":"publisher","first-page":"1844","DOI":"10.18632\/aging.101020","article-title":"DNA methylation-based measures of biological age: meta-analysis predicting time to death","volume":"8","author":"Chen","year":"2016","journal-title":"Aging (Albany NY)"},{"key":"B9","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1136\/heartjnl-2019-315629","article-title":"Marital status, telomere length and cardiovascular disease risk in a Swedish prospective cohort","volume":"106","author":"Chen","year":"2020","journal-title":"Heart"},{"key":"B10","doi-asserted-by":"publisher","first-page":"e2111813","DOI":"10.1001\/jamanetworkopen.2021.11813","article-title":"Assessment of modifiable factors for the association of marital status with cancer-specific survival","volume":"4","author":"Chen","year":"2021","journal-title":"JAMA Netw. Open"},{"key":"B11","doi-asserted-by":"publisher","first-page":"e319","DOI":"10.1542\/hpeds.2023-007259","article-title":"How to interact with interactions: what Clinicians should know about statistical interactions","volume":"13","author":"Cotter","year":"2023","journal-title":"Hosp. Pediatr."},{"key":"B12","doi-asserted-by":"publisher","first-page":"100774","DOI":"10.1016\/j.bbih.2024.100774","article-title":"Multi-discrimination exposure and biological aging: results from the midlife in the United States study","volume":"39","author":"Cuevas","year":"2024","journal-title":"Brain, Behav. and Immun. - Health"},{"key":"B13","doi-asserted-by":"publisher","first-page":"1535524","DOI":"10.3389\/fpubh.2025.1535524","article-title":"Association of marital status with DNA methylation-based biological age among US older adults","volume":"13","author":"Cui","year":"2025","journal-title":"Front. Public Health"},{"key":"B14","doi-asserted-by":"publisher","first-page":"439","DOI":"10.1093\/sf\/sow040","article-title":"Race, marital history, and risks for stroke in US older adults","volume":"95","author":"Dupre","year":"2016","journal-title":"Soc. Forces"},{"key":"B15","doi-asserted-by":"publisher","first-page":"e2215840120","DOI":"10.1073\/pnas.2215840120","article-title":"Epigenetic-based age acceleration in a representative sample of older Americans: associations with aging-related morbidity and mortality","volume":"120","author":"Faul","year":"2023","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B16","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1007\/s10680-017-9423-7","article-title":"Mortality differences by partnership status in England and Wales: the effect of living arrangements or health selection?","volume":"34","author":"Franke","year":"2017","journal-title":"Eur. J. Popul."},{"key":"B17","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1037\/pag0000822","article-title":"Loneliness, epigenetic age acceleration, and chronic health conditions","volume":"39","author":"Freilich","year":"2024","journal-title":"Psychol. Aging"},{"key":"B18","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1198\/000313006X152649","article-title":"The difference between significant and not significant is not itself statistically significant","volume":"60","author":"Gelman","year":"2006","journal-title":"Am. Stat."},{"key":"B19","doi-asserted-by":"publisher","first-page":"Article 101194","DOI":"10.1016\/j.bbih.2026.101194","article-title":"The role of health behaviors in links between stress and epigenetic aging","volume":"52","author":"Goering","year":"2026","journal-title":"Brain, Behav. and Immun. - Health"},{"key":"B20","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1016\/j.molcel.2012.10.016","article-title":"Genome-wide methylation profiles reveal quantitative views of human aging rates","volume":"49","author":"Hannum","year":"2013","journal-title":"Mol. Cell."},{"key":"B21","volume-title":"The Second Shift: Working Families and the Revolution at Home","author":"Hochschild","year":"1989"},{"key":"B22","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1007\/s12160-008-9018-y","article-title":"Is there something unique about marriage? The relative impact of marital status, relationship quality, and network social support on ambulatory blood pressure and mental health","volume":"35","author":"Holt-Lunstad","year":"2008","journal-title":"Ann. Behav. Med."},{"key":"B23","doi-asserted-by":"publisher","first-page":"R115","DOI":"10.1186\/gb-2013-14-10-r115","article-title":"DNA methylation age of human tissues and cell types","volume":"14","author":"Horvath","year":"2013","journal-title":"Genome Biol."},{"key":"B24","doi-asserted-by":"publisher","first-page":"100642","DOI":"10.1016\/j.ssmph.2020.100642","article-title":"Life expectancy and active life expectancy by marital status among older U.S. adults: results from the U.S. medicare health outcome survey (HOS)","volume":"12","author":"Jia","year":"2020","journal-title":"SSM Popul. Health"},{"key":"B25","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1016\/j.ebiom.2017.03.046","article-title":"Biological age predictors","volume":"21","author":"Jylh\u00e4v\u00e4","year":"2017","journal-title":"EBioMedicine"},{"key":"B26","doi-asserted-by":"publisher","first-page":"484","DOI":"10.1038\/s43587-022-00220-0","article-title":"The relationship between epigenetic age and the hallmarks of aging in human cells","volume":"2","author":"Kabacik","year":"2022","journal-title":"Nat. Aging"},{"key":"B27","doi-asserted-by":"publisher","first-page":"472","DOI":"10.1037\/0033-2909.127.4.472","article-title":"Marriage and health: his and hers","volume":"127","author":"Kiecolt-Glaser","year":"2001","journal-title":"Psychol. Bull."},{"key":"B28","doi-asserted-by":"publisher","first-page":"322","DOI":"10.1016\/j.jamda.2019.09.017","article-title":"Marital status and risk of physical frailty: a systematic review and meta-analysis","volume":"21","author":"Kojima","year":"2020","journal-title":"J. Am. Med. Dir. Assoc."},{"key":"B29","doi-asserted-by":"publisher","first-page":"1685","DOI":"10.1002\/cam4.5003","article-title":"Marital status and survival in cancer patients: a systematic review and meta-analysis","volume":"12","author":"Krajc","year":"2023","journal-title":"Cancer Med."},{"key":"B30","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1146\/annurev-publhealth-060222-015657","article-title":"Quantification of epigenetic aging in public health","volume":"46","author":"Kusters","year":"2025","journal-title":"Annu. Rev. Public Health"},{"key":"B31","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1037\/0882-7974.8.2.301","article-title":"Long-term marriage: age, gender, and satisfaction","volume":"8","author":"Levenson","year":"1993","journal-title":"Psychol. Aging"},{"key":"B32","doi-asserted-by":"publisher","first-page":"573","DOI":"10.18632\/aging.101414","article-title":"An epigenetic biomarker of aging for lifespan and healthspan","volume":"10","author":"Levine","year":"2018","journal-title":"Aging (Albany NY)"},{"key":"B33","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1177\/002214650804900301","article-title":"The times they are a changin': marital status and health differentials from 1972 to 2003","volume":"49","author":"Liu","year":"2008","journal-title":"J. Health Soc. Behav."},{"key":"B34","doi-asserted-by":"publisher","first-page":"303","DOI":"10.18632\/aging.101684","article-title":"DNA methylation GrimAge strongly predicts lifespan and healthspan","volume":"11","author":"Lu","year":"2019","journal-title":"Aging (Albany NY)"},{"key":"B35","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1093\/ageing\/afq118","article-title":"Leukocyte telomere length and marital status among middle-aged adults","volume":"40","author":"Mainous","year":"2011","journal-title":"Age Ageing"},{"key":"B36","doi-asserted-by":"publisher","first-page":"384","DOI":"10.1097\/PSY.0000000000000798","article-title":"Marital status, close relationships, and all-cause mortality: results from a 10-year study of nationally representative older adults","volume":"82","author":"Manvelian","year":"2020","journal-title":"Psychosom. Med."},{"key":"B37","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1016\/j.socscimed.2006.08.031","article-title":"Marital status and mortality in the elderly: a systematic review and meta-analysis","volume":"64","author":"Manzoli","year":"2007","journal-title":"Soc. Sci. Med."},{"key":"B38","doi-asserted-by":"publisher","first-page":"116990","DOI":"10.1016\/j.socscimed.2024.116990","article-title":"Associations between epigenetic age acceleration and longitudinal measures of psychosocioeconomic stress and status","volume":"352","author":"Markon","year":"2024","journal-title":"Soc. Sci. and Med."},{"key":"B39","doi-asserted-by":"publisher","first-page":"e0324156","DOI":"10.1371\/journal.pone.0324156","article-title":"Aging dimensions and markers as relative predictors of mortality in a longitudinal epidemiological sample","volume":"20","author":"Markon","year":"2025","journal-title":"PLoS ONE"},{"key":"B40","doi-asserted-by":"publisher","first-page":"20480040251396281","DOI":"10.1177\/20480040251396281","article-title":"The association between marital status and the risk of cardiovascular, cancer, and all-cause mortality: an updated systematic review and meta-analysis","volume":"14","author":"Mohammad Hashem","year":"2025","journal-title":"JRSM Cardiovasc. Dis."},{"key":"B41","doi-asserted-by":"publisher","first-page":"320","DOI":"10.1007\/s11199-011-0008-3","article-title":"Why do men benefit more from marriage than do women? Thinking more broadly about interpersonal processes that occur within and outside of marriage","volume":"65","author":"Monin","year":"2011","journal-title":"Sex. Roles"},{"key":"B42","doi-asserted-by":"publisher","first-page":"246","DOI":"10.22045\/ibj.2016.01","article-title":"Role of epigenetics in biology and human diseases","volume":"20","author":"Moosavi","year":"2016","journal-title":"Iran. Biomed. J."},{"key":"B43","doi-asserted-by":"publisher","first-page":"R741","DOI":"10.1016\/j.cub.2012.07.024","article-title":"Ageing as a risk factor for disease","volume":"22","author":"Niccoli","year":"2012","journal-title":"Curr. Biol."},{"key":"B44","doi-asserted-by":"publisher","first-page":"832","DOI":"10.2307\/353305","article-title":"Marital communication in the eighties","volume":"52","author":"Noller","year":"1990","journal-title":"J. Marriage Fam."},{"key":"B45","doi-asserted-by":"publisher","first-page":"101096","DOI":"10.1016\/j.bbih.2025.101096","article-title":"Cumulative social advantage is associated with slower epigenetic aging and lower systemic inflammation","volume":"48","author":"Ong","year":"2025","journal-title":"Brain, Behav. and Immun. - Health"},{"key":"B46","volume-title":"Weighting the MIDUS Refresher Data","author":"Palit","year":"2016"},{"key":"B47","doi-asserted-by":"publisher","first-page":"P33","DOI":"10.1093\/geronb\/61.1.P33","article-title":"Gender differences in caregiver stressors, social resources, and health: an updated meta-analysis","volume":"61","author":"Pinquart","year":"2006","journal-title":"J. Gerontol. B Psychol. Sci. Soc. Sci."},{"key":"B48","doi-asserted-by":"publisher","first-page":"Article 22284","DOI":"10.1038\/s41598-025-07222-z","article-title":"Associations between positive and negative social experiences and epigenetic aging","volume":"15","author":"Prigerson","year":"2025","journal-title":"Sci. Rep."},{"key":"B49","doi-asserted-by":"publisher","first-page":"481","DOI":"10.1007\/s13524-011-0032-5","article-title":"The protective effect of marriage for survival: a review and update","volume":"48","author":"Rendall","year":"2011","journal-title":"Demography"},{"key":"B50","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1016\/j.bbi.2023.09.001","article-title":"Social relationships and epigenetic aging in older adulthood: results from the health and retirement study","volume":"114","author":"Rentscher","year":"2023","journal-title":"Brain Behav. Immun."},{"key":"B51","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1016\/j.maturitas.2012.08.007","article-title":"Marital status, health and mortality","volume":"73","author":"Robards","year":"2012","journal-title":"Maturitas"},{"key":"B52","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1177\/0963721414549043","article-title":"Marital quality and health: implications for marriage in the 21st century","volume":"23","author":"Robles","year":"2014","journal-title":"Curr. Dir. Psychol. Sci."},{"key":"B53","doi-asserted-by":"publisher","first-page":"1249","DOI":"10.1080\/17501911.2025.2568301","article-title":"Relationship stress and epigenetic age acceleration among older U.S. adults in the midlife in the United States study","volume":"17","author":"Rodrigues","year":"2025","journal-title":"Epigenomics"},{"key":"B54","doi-asserted-by":"publisher","first-page":"575","DOI":"10.1007\/s13524-012-0096-x","article-title":"Widowhood and mortality: a meta-analysis and meta-regression","volume":"49","author":"Roelfs","year":"2012","journal-title":"Demography"},{"key":"B55","volume-title":"Midlife in the United States (MIDUS 2), 2004-2006","author":"Ryff","year":""},{"key":"B56","volume-title":"Midlife in the United States (MIDUS Refresher 1), 2011-2014","author":"Ryff","year":""},{"key":"B57","volume-title":"Midlife in the United States (MIDUS 2): Biomarker Project, 2004-2009","author":"Ryff","year":"2019"},{"key":"B58","doi-asserted-by":"publisher","first-page":"e005890","DOI":"10.1161\/JAHA.117.005890","article-title":"Marital status and outcomes in patients with cardiovascular disease","volume":"6","author":"Schultz","year":"2017","journal-title":"J. Am. Heart Assoc."},{"key":"B59","doi-asserted-by":"publisher","first-page":"2215","DOI":"10.1001\/jama.282.23.2215","article-title":"Caregiving as a risk factor for mortality: the caregiver health effects study","volume":"282","author":"Schulz","year":"1999","journal-title":"JAMA"},{"key":"B60","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1038\/s41576-022-00477-6","article-title":"Making sense of the ageing methylome","volume":"23","author":"Seale","year":"2022","journal-title":"Nat. Rev. Genet."},{"key":"B61","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1097\/MCO.0b013e32834121b1","article-title":"Telomeres, lifestyle, cancer, and aging","volume":"14","author":"Shammas","year":"2011","journal-title":"Curr. Opin. Clin. Nutr. Metab. Care"},{"key":"B62","doi-asserted-by":"publisher","first-page":"101892","DOI":"10.1016\/j.ssmph.2025.101892","article-title":"Social support and epigenetic aging at the intersections of race, ethnicity, and gender: findings from NHANES 1999-2002","volume":"33","author":"Shen","year":"2025","journal-title":"SSM - Population Health"},{"key":"B63","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1007\/s12160-012-9457-3","article-title":"Consistency and timing of marital transitions and survival during midlife: the role of personality and health risk behaviors","volume":"45","author":"Siegler","year":"2013","journal-title":"Ann. Behav. Med."},{"key":"B64","doi-asserted-by":"publisher","first-page":"e22","DOI":"10.1136\/jech.2010.128397","article-title":"Marital status, living arrangement and mortality: does the association vary by gender?","volume":"66","author":"Staehelin","year":"2012","journal-title":"J. Epidemiol. Community Health"},{"key":"B65","doi-asserted-by":"publisher","first-page":"1241","DOI":"10.1007\/s11357-025-01728-0","article-title":"Epigenetic aging mediates the association between life course socioeconomic status and decrements in kidney function across a decade","volume":"48","author":"Surachman","year":"2026","journal-title":"GeroScience"},{"key":"B66","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1007\/s10522-025-10307-x","article-title":"Cortisol, DHEAS, and the cortisol\/DHEAS ratio as predictors of epigenetic age acceleration","volume":"26","author":"Takeshita","year":"2025","journal-title":"Biogerontology"},{"key":"B67","doi-asserted-by":"publisher","first-page":"100948","DOI":"10.1016\/j.pmedr.2019.100948","article-title":"Does marriage matter? Racial differences in allostatic load among women","volume":"15","author":"Tobin","year":"2019","journal-title":"Prev. Med. Rep."},{"key":"B68","doi-asserted-by":"publisher","first-page":"927","DOI":"10.1089\/jwh.2019.8095","article-title":"Gender differences in the relationship between marital status and the development of frailty: a Swedish longitudinal population-based study","volume":"29","author":"Trevisan","year":"2020","journal-title":"J. Womens Health"},{"key":"B69","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1017\/S0021932018000147","article-title":"Gender differences in the association between marital status and hypertension in Ghana","volume":"51","author":"Tuoyire","year":"2018","journal-title":"J. Biosoc. Sci."},{"key":"B70","doi-asserted-by":"publisher","first-page":"404","DOI":"10.1111\/jomf.12640","article-title":"Family matters: research on family ties and health, 2010-2020","volume":"82","author":"Umberson","year":"2020","journal-title":"J. Marriage Fam."},{"key":"B71","volume-title":"MIDUS genomics project DNA methylation age data documentation","year":"2023"},{"key":"B72","doi-asserted-by":"publisher","first-page":"267","DOI":"10.2307\/351696","article-title":"Marital status and health","volume":"41","author":"Verbrugge","year":"1979","journal-title":"J. Marriage Fam."},{"key":"B73","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1016\/j.canep.2011.02.004","article-title":"Marital status and Colon cancer outcomes in US surveillance, epidemiology and end results registries: does marriage affect cancer survival by gender and stage?","volume":"35","author":"Wang","year":"2011","journal-title":"Cancer Epidemiol."},{"key":"B74","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1186\/s41256-020-00133-8","article-title":"Sex differences in the association between marital status and the risk of cardiovascular, cancer, and all-cause mortality: a systematic review and meta-analysis of 7,881,040 individuals","volume":"5","author":"Wang","year":"2020","journal-title":"Glob. Health Res. Policy"},{"key":"B75","doi-asserted-by":"publisher","first-page":"101551","DOI":"10.1016\/j.ssmph.2023.101551","article-title":"Partnership status and positive DNA methylation age acceleration across the adult lifespan in the UK","volume":"24","author":"Wang","year":"2023","journal-title":"SSM Popul. Health"},{"key":"B76","doi-asserted-by":"publisher","first-page":"112912","DOI":"10.1016\/j.exger.2025.112912","article-title":"Gender disparities in marital status and risk of developing age acceleration: findings from NHANES 2015-2018","volume":"211","author":"Wang","year":"2025","journal-title":"Exp. Gerontol."},{"key":"B77","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1007\/s11199-011-9968-6","article-title":"Toward an understanding of gender differences in the impact of marital conflict on health","volume":"65","author":"Wanic","year":"2011","journal-title":"Sex. Roles"},{"key":"B78","volume-title":"Midlife in the United States (MIDUS Refresher): Biomarker Project, 2012-2016","author":"Weinstein","year":"2019"},{"key":"B79","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1016\/j.socscimed.2016.03.029","article-title":"Marital disruption is associated with shorter salivary telomere length in a probability sample of older adults","volume":"157","author":"Whisman","year":"2016","journal-title":"Soc. Sci. Med."},{"key":"B80","doi-asserted-by":"publisher","first-page":"25327207","DOI":"10.1101\/2025.05.08.25327207","article-title":"Social determinants of health and epigenetic clocks: meta-Analysis of 140 studies","volume":"5","author":"Willems","year":"2025","journal-title":"medRxiv The Preprint Server Health Sciences"},{"key":"B81","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1177\/002214650404500106","article-title":"Marital status, marital transitions, and health: a gendered life course perspective","volume":"45","author":"Williams","year":"2004","journal-title":"J. Health Soc. Behav."},{"key":"B82","doi-asserted-by":"publisher","first-page":"1937","DOI":"10.1136\/heartjnl-2018-313005","article-title":"Marital status and risk of cardiovascular diseases: a systematic review and meta-analysis","volume":"104","author":"Wong","year":"2018","journal-title":"Heart"},{"key":"B83","doi-asserted-by":"publisher","first-page":"234","DOI":"10.1093\/ageing\/afs122","article-title":"Older adults with higher income or marriage have longer telomeres","volume":"42","author":"Yen","year":"2013","journal-title":"Age Ageing"},{"key":"B84","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1177\/08982643221104928","article-title":"Current marital status and epigenetic clocks among older adults in the United States: evidence from the health and retirement study","volume":"35","author":"Yu","year":"2023","journal-title":"J. Aging Health"},{"key":"B85","doi-asserted-by":"publisher","first-page":"627","DOI":"10.1007\/s00038-020-01371-w","article-title":"Marital status, living arrangements, and mortality in middle and older age in Europe","volume":"65","author":"Zueras","year":"2020","journal-title":"Int. J. Public Health"}],"container-title":["Frontiers in Aging"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fragi.2026.1931190\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T05:34:41Z","timestamp":1788759281000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fragi.2026.1931190\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,7]]},"references-count":85,"alternative-id":["10.3389\/fragi.2026.1931190"],"URL":"https:\/\/doi.org\/10.3389\/fragi.2026.1931190","relation":{},"ISSN":["2673-6217"],"issn-type":[{"value":"2673-6217","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,7]]},"article-number":"1931190"}}