{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T13:35:40Z","timestamp":1786628140399,"version":"build-2736575974"},"reference-count":51,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T00:00:00Z","timestamp":1786579200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Dement."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Early detection and interdisciplinary management of cognitive impairment are essential, particularly in socioeconomically vulnerable populations with limited access to specialized care. To address this need, a Memory Clinic was established in 2016 within the Argentine public healthcare system in Florencio Varela. This region reflects a condition of structural poverty, where 16.2% of the population lives in poverty according to Unsatisfied Basic Needs (UBN) and over 60% of residents lack essential services.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The study included 1,204 individuals (852 women, 353 men) with a mean age of 72\u202fyears and 6\u202fyears of education, most of whom attended through self-motivation based on memory complaints. Based on cumulative experience, a work protocol tailored to the local population was established, comprising a cognitive battery (MMSE, ACE-R, FAB, CDR, FAQ, Zarit Scale, NPI-Q), neurological and functional evaluation, laboratory testing, and neuroimaging. Diagnoses are determined by consensus in weekly interdisciplinary meetings. Additionally, a cognitive reserve questionnaire was culturally adapted, implemented, and tested in a subpopulation of 315 people. Over the past three years, the clinic also contributed to the formation of GeNED.ar (Genetics and Neuroimaging in Aging and Dementia in Argentina), a national cohort study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Evaluated patients received a definitive diagnosis along with guidance on healthy aging and, when necessary, appropriate pharmacological treatment or cognitive stimulation therapy. The implementation of the adapted questionnaire revealed a significantly lower cognitive reserve in patients with dementia. Furthermore, active participation in research projects like GeNED.ar demonstrated enhancements in clinical care, supported staff training, and promoted alignment with international standards.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>As the only public healthcare center of its kind in the region, this Memory Clinic provides high-quality, research-integrated cognitive care to a vulnerable elderly population. This center offers a successful and replicable model for similar socioeconomic contexts across Latin America.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/frdem.2026.1881788","type":"journal-article","created":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T12:56:25Z","timestamp":1786625785000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Diagnostic and treatment strategies in a memory clinic for older adults in a region with a predominantly low-income population"],"prefix":"10.3389","volume":"5","author":[{"given":"Patricia","family":"Solis","sequence":"first","affiliation":[{"name":"Studies in Neuroscience and Complex Systems Unit (ENyS-CONICET-Universidad Nacional Arturo Jauretche-Hospital El Cruce)","place":["Florencio Varela, Argentina"]},{"name":"Memory Clinic, Atenci\u00f3n M\u00e9dica Integral (AMI), Hospital El Cruce","place":["Florencio Varela, Buenos Aires, Argentina"]},{"name":"Department of Neuroscience, Hospital El Cruce","place":["Buenos Aires, Argentina"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ines","family":"Mintz","sequence":"additional","affiliation":[{"name":"Studies in Neuroscience and Complex Systems Unit (ENyS-CONICET-Universidad Nacional Arturo Jauretche-Hospital El Cruce)","place":["Florencio Varela, Argentina"]},{"name":"Memory Clinic, Atenci\u00f3n M\u00e9dica Integral (AMI), Hospital El Cruce","place":["Florencio Varela, Buenos Aires, Argentina"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nancy","family":"Medel","sequence":"additional","affiliation":[{"name":"Studies in Neuroscience and Complex Systems Unit (ENyS-CONICET-Universidad Nacional Arturo Jauretche-Hospital El Cruce)","place":["Florencio Varela, Argentina"]},{"name":"Memory Clinic, Atenci\u00f3n M\u00e9dica Integral (AMI), Hospital El Cruce","place":["Florencio Varela, Buenos Aires, Argentina"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zulma","family":"Sevillano","sequence":"additional","affiliation":[{"name":"Studies in Neuroscience and Complex Systems Unit (ENyS-CONICET-Universidad Nacional Arturo Jauretche-Hospital El Cruce)","place":["Florencio Varela, Argentina"]},{"name":"Memory Clinic, Atenci\u00f3n M\u00e9dica Integral (AMI), Hospital El Cruce","place":["Florencio Varela, Buenos Aires, Argentina"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julieta","family":"Lisso","sequence":"additional","affiliation":[{"name":"Studies in Neuroscience and Complex Systems Unit (ENyS-CONICET-Universidad Nacional Arturo Jauretche-Hospital El Cruce)","place":["Florencio Varela, Argentina"]},{"name":"Memory Clinic, Atenci\u00f3n M\u00e9dica Integral (AMI), Hospital El Cruce","place":["Florencio Varela, Buenos Aires, Argentina"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Irureta","sequence":"additional","affiliation":[{"name":"Studies in Neuroscience and Complex Systems Unit (ENyS-CONICET-Universidad Nacional Arturo Jauretche-Hospital El Cruce)","place":["Florencio Varela, Argentina"]},{"name":"Memory Clinic, Atenci\u00f3n M\u00e9dica Integral (AMI), Hospital El Cruce","place":["Florencio Varela, Buenos Aires, Argentina"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mauricio Federico","family":"Zalazar-Jaime","sequence":"additional","affiliation":[{"name":"Facultad de Psicolog\u00eda, Universidad Nacional de C\u00f3rdoba","place":["C\u00f3rdoba, Argentina"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brenda","family":"Giagante","sequence":"additional","affiliation":[{"name":"Studies in Neuroscience and Complex Systems Unit (ENyS-CONICET-Universidad Nacional Arturo Jauretche-Hospital El Cruce)","place":["Florencio Varela, 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