{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T02:51:06Z","timestamp":1790823066615,"version":"4.1.0"},"reference-count":22,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001321","name":"National Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001321","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Oral. Health"],"abstract":"<jats:p>Oral mucosal lesions can be uncomfortable and can result in a poorer oral health related quality of life. This can be seen especially in edentulous patients who are mostly elderly and have comorbid diseases such as Diabetes Mellitus, which can impair their ability to withstand oral infections. In South Africa, one of the most unequal countries in the world, almost 50% of the population is edentulous and this prevalence increases as age increases. The aim of this cross-sectional study was to determine the prevalence of denture-related stomatitis in subjects who presented to a tertiary institution in Cape Town, South Africa for new complete dentures and to determine the risk indicators associated with it. Three hundred and ninety-six folders of participants who received complete dentures during the period 2014\u20132019 were included in this study. Categorical data was displayed as frequencies and percentages and a multiple adjusted logistic regression was used to determine associations between Candida and certain risk indicators. The prevalence of denture-related stomatitis was 25.76% (<jats:italic>n<\/jats:italic> = 102). Almost 75% (<jats:italic>n<\/jats:italic> = 225) females and 72.63% (<jats:italic>n<\/jats:italic> = 69) males had no denture-related stomatitis. The most common site for candidiasis in this population was the palate and tonsillar area (40.2%, <jats:italic>n<\/jats:italic> = 41) and the least common site was the upper ridge (2.94%, <jats:italic>n<\/jats:italic> = 3). Candidiasis, in edentulous patients are highly prevalent in this population and more needs to be done to prevent it.<\/jats:p>","DOI":"10.3389\/froh.2021.772679","type":"journal-article","created":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T21:34:39Z","timestamp":1638394479000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":21,"title":["Prevalence of Denture-Related Stomatitis in Edentulous Patients at a Tertiary Dental Teaching Hospital"],"prefix":"10.3389","volume":"2","author":[{"given":"Razia Zulfikar","family":"Adam","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Faheema","family":"Kimmie-Dhansay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2021,12,1]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1016\/S0140-6736(09)62177-2","article-title":"Ageing and health","volume":"375","author":"Olshansky","year":"2010","journal-title":"Lancet."},{"key":"B2","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1016\/S0140-6736(19)31146-8","article-title":"Oral diseases: a global public health challenge","volume":"394","author":"Peres","year":"2019","journal-title":"Lancet."},{"key":"B3","unstructured":"12GINI index (World Bank estimate) - South Africa2020"},{"key":"B4","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1111\/j.1875-595X.2004.tb00014.x","article-title":"Oral health in South Africa","volume":"54","author":"van Wyk","year":"2004","journal-title":"Int Dent J."},{"key":"B5","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1111\/idj.12538","article-title":"Dental caries in a South African adult population: findings from the Cape Town Vascular and Metabolic Health Study","volume":"70","author":"Chikte","year":"2020","journal-title":"Int Dent J."},{"key":"B6","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1186\/s12903-016-0256-2","article-title":"Common risk factors and edentulism in adults, aged 50 years and over, in China, Ghana, India and South Africa: Results from the WHO Study on global AGEing and adult health (SAGE)","volume":"17","author":"Kailembo","year":"2016","journal-title":"BMC Oral Health."},{"key":"B7","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1111\/ger.12541","article-title":"Edentulism-free life expectancy among older Brazilian adults: SABE study, 2006-2016","volume":"38","author":"Oliveira","year":"2021","journal-title":"Gerodontology."},{"key":"B8","first-page":"264","article-title":"The impact of new complete dentures on oral health-related quality of life","volume":"62","author":"Adam","year":"2007","journal-title":"SADJ."},{"key":"B9","first-page":"85","article-title":"[Clinical analysis of denture-related oral mucosal lesions in 185 patients with removable denture]","volume":"29","author":"Wang","year":"2020","journal-title":"Shanghai Kou Qiang Yi Xue."},{"key":"B10","doi-asserted-by":"publisher","first-page":"35","DOI":"10.2478\/bjdm-2020-0026","article-title":"The relationship of oral mucosal lesions and removable prostheses: quantitative and qualitative study","volume":"24","author":"\u00d6zkan","year":"2020","journal-title":"Balk J Dent Med."},{"key":"B11","doi-asserted-by":"publisher","first-page":"24","DOI":"10.15171\/joddd.2019.004","article-title":"Oral mucosal lesions and risk factors in elderly dental patients","volume":"13","author":"Bozdemir","year":"2019","journal-title":"J Dent Res Dent Clin Dent Prospects."},{"key":"B12","doi-asserted-by":"publisher","first-page":"394","DOI":"10.17126\/joralres.2019.061","article-title":"The most common oral lesions in edentulous patients with total prostheses","volume":"8","author":"Barrera","year":"2020","journal-title":"J Oral Res."},{"key":"B13","doi-asserted-by":"publisher","first-page":"e305","DOI":"10.4317\/medoral.22826","article-title":"Analysis of risk factors for maxillary denture-related oral mucosal lesions: a cross-sectional study","volume":"24","author":"Brantes","year":"2019","journal-title":"Med Oral Patol Oral y Cir Bucal."},{"key":"B14","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1111\/jopr.12208","article-title":"Association between oral mucosal lesions and hygiene habits in a population of removable prosthesis wearers","volume":"24","author":"Ercalik-Yalcinkaya","year":"2015","journal-title":"J Prosthodont."},{"key":"B15","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1111\/j.1532-849X.2011.00698.x","article-title":"Epidemiology and etiology of denture stomatitis","volume":"20","author":"Gendreau","year":"2011","journal-title":"J Prosthodont."},{"key":"B16","doi-asserted-by":"publisher","first-page":"83","DOI":"10.4103\/0970-258X.310983","article-title":"Oral healthcare needs of the institutionalized ageing population in Tamil Nadu","volume":"33","author":"Anu","year":"2020","journal-title":"Natl Med J India"},{"key":"B17","doi-asserted-by":"publisher","first-page":"233372142092518","DOI":"10.1177\/2333721420925189","article-title":"Prevalence of oral mucosal lesions among the institutionalized elderly population in Lebanon","volume":"6","author":"Choufani","year":"2020","journal-title":"Gerontol Geriatr Med."},{"key":"B18","unstructured":"Du ToitAC\n            ClaassenA\n          An Oral Pathological Profile for the Preprosthetic Evaluation of Edentulous Patients in the Western Cape of South Africa and the Implications for Training2003"},{"key":"B19","doi-asserted-by":"publisher","first-page":"580","DOI":"10.1111\/jopr.12610","article-title":"Laboratory-based investigation of denture sonication method in patients with Candida-Associated Denture Stomatitis","volume":"28","author":"Peri\u0107","year":"2019","journal-title":"J Prosthodont."},{"key":"B20","doi-asserted-by":"publisher","first-page":"554","DOI":"10.3290\/j.qi.a44630","article-title":"Denture-related stomatitis in new complete denture wearers and its association with Candida species colonization: a prospective case-series","volume":"51","author":"Mousa","year":"2020","journal-title":"Quintessence Int."},{"key":"B21","doi-asserted-by":"publisher","first-page":"653","DOI":"10.1016\/j.prosdent.2019.10.004","article-title":"Chemical cleaning methods for prostheses colonized by Candida spp.: a systematic review","volume":"124","author":"Ribeiro Rocha","year":"2020","journal-title":"J Prosthetic Dentistry."},{"key":"B22","doi-asserted-by":"publisher","first-page":"30808","DOI":"10.1016\/j.prosdent.2020.12.018","article-title":"Effect of local hygiene protocols on denture-related stomatitis, biofilm, microbial load, and odor: a randomized controlled trial","author":"Araujo","year":"2021","journal-title":"J Prosthet Dent"}],"container-title":["Frontiers in Oral Health"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/froh.2021.772679\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T21:34:42Z","timestamp":1638394482000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/froh.2021.772679\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,1]]},"references-count":22,"alternative-id":["10.3389\/froh.2021.772679"],"URL":"https:\/\/doi.org\/10.3389\/froh.2021.772679","relation":{},"ISSN":["2673-4842"],"issn-type":[{"value":"2673-4842","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,12,1]]},"article-number":"772679"}}