{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T00:40:55Z","timestamp":1792975255586,"version":"4.5.0"},"reference-count":63,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T00:00:00Z","timestamp":1707436800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Oral. Health"],"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Impacted lower third molar surgeries involve trauma in a highly vascularized zone with loose connective tissue leading to inflammatory sequelae including postoperative pain, swelling, trismus and generalised oral dysfunction during the post-operative phase. In minor oral surgical procedures, an all-inclusive method to protract anaesthesia and reduce the inevitable post-operative sequelae is yet to be explored substantially.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>To evaluate the efficacy of dexamethasone added to local anaesthetics in extending the depth and duration of anaesthesia and decreasing the postoperative complications after surgical removal of impacted third molars.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methodology<\/jats:title><jats:p>A controlled, randomized, split-mouth, double-blind prospective study involving lower third molar surgery was performed in 35 patients wherein the test group (Group I) received 8\u2005mg dexamethasone added to 2\u2005ml of 2% lignocaine with epinephrine and the control group (Group II) received 2\u2005ml of sterile water added to 2\u2005ml of 2% lignocaine with epinephrine. Onset and duration of anaesthesia were evaluated; followed by evaluation of pain, swelling and trismus for 7 days post-surgery, using independent <jats:italic>t<\/jats:italic>-test and ANOVA for repeated measures.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Test group had a faster onset of anaesthesia by 69\u2005s and a lengthier duration of 128.4\u2005min (<jats:italic>p<\/jats:italic>\u2009&amp;lt;\u20090.001). Pain scores (Visual Analogue Scale) in the first 24\u2005h were 4.9 and 7.5 in the test and control group respectively (<jats:italic>p<\/jats:italic>\u2009&amp;lt;\u20090.001). The average dosing of analgesics until postoperative day 7 in the test and control group were 12.6 and 18.4 respectively (<jats:italic>p<\/jats:italic>\u2009&amp;lt;\u20090.001). The swelling was significantly lesser in the test group, in addition, trismus was significantly lesser by 1\u2005cm on postoperative days 1 and 2 and 0.2\u2005cm on day 7.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The addition of dexamethasone to lignocaine in the nerve block reduces the time of onset and significantly prolongs the duration of anaesthesia with decreased pain, swelling and trismus. Steroids mixed directly with the local anaesthetic agent can minimise the post-operative sequelae associated with third molar surgery with a single needle prick.<\/jats:p><\/jats:sec>","DOI":"10.3389\/froh.2024.1349832","type":"journal-article","created":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T05:07:32Z","timestamp":1707455252000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":8,"title":["A comparative evaluation of the effect of addition of 8\u2005mg dexamethasone to 2% lignocaine with adrenaline in mandibular third molar surgery: a split mouth randomised double blind study"],"prefix":"10.3389","volume":"5","author":[{"given":"P.","family":"Poorna","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Premalatha","family":"Shetty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veerbhadra","family":"Kalyani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sameep","family":"Shetty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madhusudan","family":"Upadya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prasanna","family":"Mithra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2024,2,9]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"529","DOI":"10.1016\/j.ijom.2019.10.006","article-title":"Comparison of intraosseous and submucosal dexamethasone injection in mandibular third molar surgery: a split-mouth randomized clinical trial","volume":"49","author":"Kaewkumnert","year":"2020","journal-title":"Int J Oral Maxillofac Surg"},{"key":"B2","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1016\/j.jdsr.2013.07.002","article-title":"Effectiveness of preemptive analgesia on postoperative pain following third molar surgery: review of literatures","volume":"49","author":"Yamaguchi","year":"2013","journal-title":"Jpn Dent Sci Rev"},{"key":"B3","doi-asserted-by":"publisher","first-page":"567","DOI":"10.1067\/moe.2000.110034","article-title":"Lingual nerve damage after third molar extraction","volume":"90","author":"Valmeseda-Castellon","year":"2000","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"B4","doi-asserted-by":"publisher","first-page":"e74","DOI":"10.4317\/medoral.15.e74","article-title":"Complications in third molar removal: a retrospective study of 588 patients","volume":"15","author":"Contar","year":"2010","journal-title":"Med Oral Patol Oral Cir Bucal"},{"key":"B5","doi-asserted-by":"publisher","first-page":"375","DOI":"10.12968\/denu.2003.30.7.375","article-title":"Nerve damage and third molar removal","volume":"30","author":"Loescher","year":"2003","journal-title":"Dent Update"},{"key":"B6","doi-asserted-by":"publisher","first-page":"320","DOI":"10.1016\/j.ijom.2009.11.010","article-title":"Incidence of neurosensory deficits and recovery after lower third molar surgery: a prospective clinical study of 4338 cases","volume":"39","author":"Cheung","year":"2010","journal-title":"Int J Oral Maxillofac Surg"},{"key":"B7","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1016\/j.jormas.2019.06.010","article-title":"Determining the risk relationship associated with inferior alveolar nerve injury following removal of mandibular third molar teeth: a systematic review","volume":"121","author":"Kang","year":"2020","journal-title":"J Stomatol Oral Maxillofac Surg"},{"key":"B8","doi-asserted-by":"publisher","first-page":"2454","DOI":"10.4103\/jfmpc.jfmpc_188_20","article-title":"Postoperative pain, edema and trismus following third molar surgery\u2013A comparitive study between submucosal and intravenous dexamethasone","volume":"9","author":"Sreesha","year":"2020","journal-title":"J Family Med Prim Care"},{"key":"B9","doi-asserted-by":"publisher","first-page":"180","DOI":"10.4103\/0019-5049.111850","article-title":"Effect of dexamethasone added to lidocaine in supraclavicular brachial plexus block: a prospective, randomised, double-blind study","volume":"57","author":"Biradar","year":"2013","journal-title":"Indian J Anaesth"},{"key":"B10","doi-asserted-by":"publisher","first-page":"21","DOI":"10.5535\/arm.2016.40.1.21","article-title":"Crystallization of local anesthetics when mixed with corticosteroid solutions","volume":"40","author":"Hwang","year":"2016","journal-title":"Ann Rehabil Med"},{"key":"B11","doi-asserted-by":"publisher","first-page":"1157","DOI":"10.1097\/00000542-199611000-00025","article-title":"Glucocorticoids prolong rat sciatic nerve blockade in vivo from bupivacaine microspheres","volume":"85","author":"Castillo","year":"1996","journal-title":"Anesthesiology"},{"key":"B12","doi-asserted-by":"publisher","first-page":"969","DOI":"10.1097\/00000542-199810000-00022","article-title":"Prolonged intercostal nerve blockade in sheep using controlled-release of bupivacaine and dexamethasone from polymer microspheres","volume":"89","author":"Dr\u00e4ger","year":"1998","journal-title":"Anesthesiology"},{"key":"B13","doi-asserted-by":"publisher","first-page":"5","DOI":"10.2147\/lra.s59158","article-title":"Perineural but not systemic low-dose dexamethasone prolongs the duration of interscalene block with ropivacaine: a prospective randomized trial","volume":"7","author":"Kawanishi","year":"2014","journal-title":"Local Reg Anesth"},{"key":"B14","doi-asserted-by":"publisher","first-page":"130","DOI":"10.4097\/kjae.2012.62.2.130","article-title":"Dexamethasone added to levobupivacaine improves postoperative analgesia in ultrasound guided interscalene brachial plexus blockade for arthroscopic shoulder surgery","volume":"62","author":"Kim","year":"2012","journal-title":"Korean J Anesthesiol"},{"key":"B15","doi-asserted-by":"publisher","first-page":"202","DOI":"10.4103\/0259-1162.134506","article-title":"Comparative evaluation of ropivacaine and ropivacaine with dexamethasone in supraclavicular brachial plexus block for postoperative analgesia","volume":"8","author":"Kumar","year":"2014","journal-title":"Anesth: Essays Res"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD011770.pub2","article-title":"Dexamethasone as an adjuvant to peripheral nerve block","volume":"11","author":"Pehora","year":"2017","journal-title":"Cochrane Database Syst Rev"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1016\/j.bja.2023.09.022","article-title":"Prophylactic dexamethasone for rebound pain after peripheral nerve block in adult surgical patients: systematic review, meta-analysis, and trial sequential analysis of randomised controlled trials","author":"Singh","year":"2023","journal-title":"Br J Anaesth"},{"key":"B18","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1016\/j.ajoms.2021.12.004","article-title":"The efficacy of methylprednisolone versus dexamethasone in reducing postoperative sequelae after third molar surgery: a systematic review and meta-analysis","volume":"34","author":"Madhoon","year":"2022","journal-title":"J Oral Maxillofac Surg Med Pathol"},{"key":"B19","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1111\/ors.12399","article-title":"Efficacy of intravenous dexamethasone administered preoperatively and postoperatively on pain, swelling, and trismus following third molar surgery","volume":"12","author":"Giri","year":"2019","journal-title":"Oral Surg"},{"key":"B20","doi-asserted-by":"publisher","first-page":"47","DOI":"10.17245\/jdapm.2017.17.1.47","article-title":"Decreased post-operative pain using a sublingual injection of dexamethasone (8\u2005mg) in lower third molar surgery","volume":"17","author":"Gozali","year":"2017","journal-title":"J Dent Anesth Pain Med"},{"key":"B21","doi-asserted-by":"publisher","first-page":"260","DOI":"10.4103\/2231-0746.200341","article-title":"Role of addition of dexamethasone to lignocaine 2% with adrenaline in dental nerve blocks for third molar surgery: a prospective randomized control trial","volume":"6","author":"Deo","year":"2016","journal-title":"Ann Maxillofac Surg"},{"key":"B22","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1016\/j.joms.2019.10.024","article-title":"Analgesic and anti-inflammatory effects of articaine and perineural dexamethasone for mandibular third molar surgery: a randomized, double-blind study","volume":"78","author":"Atalay","year":"2020","journal-title":"J Oral Maxillofac Surg"},{"key":"B23","doi-asserted-by":"publisher","first-page":"21","DOI":"10.5535\/arm.2016.40.1.21","article-title":"Crystallization of local anaesthetics when mixed with corticosteroid solutions","volume":"40","author":"Hwang","year":"2016","journal-title":"Ann Rehabil Med"},{"key":"B24","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1213\/01.ane.0000189055.06729.0a","article-title":"Dexamethasone added to lidocaine prolongs brachial plexus blockade","volume":"102","author":"Movafegh","year":"2006","journal-title":"Anesth Analg"},{"key":"B25","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1007\/s10006-011-0290-9","article-title":"Effect of two routes of administration of dexamethasone on pain, edema, and trismus in impacted lower third molar surgery","volume":"15","author":"Antunes","year":"2011","journal-title":"Oral Maxillofac Surg"},{"key":"B26","doi-asserted-by":"publisher","first-page":"e342","DOI":"10.1016\/j.oooo.2012.02.027","article-title":"Update on the use of corticosteroids in third molar surgery: systematic review of the literature","volume":"116","author":"Herrera-Briones","year":"2013","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol"},{"key":"B27","doi-asserted-by":"publisher","first-page":"341","DOI":"10.5125\/jkaoms.2021.47.5.341","article-title":"Review of dexamethasone administration for management of complications in postoperative third molar surgery","volume":"47","author":"Selvido","year":"2021","journal-title":"J Korean Assoc Oral Maxillofac Surg"},{"key":"B28","doi-asserted-by":"publisher","first-page":"594","DOI":"10.1016\/0030-4220(75)90369-2","article-title":"The use of intraoral dexamethasone after extraction of mandibular third molars","volume":"40","author":"Messer","year":"1975","journal-title":"Oral Surg Oral Med Oral Pathol"},{"key":"B29","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1016\/j.jsbmb.2010.02.018","article-title":"Mechanisms and resistance in glucocorticoid control of inflammation","volume":"120","author":"Barnes","year":"2010","journal-title":"J Steroid Biochem Mol Biol"},{"key":"B30","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1590\/S1806-83242013005000012","article-title":"Comparative analysis of preemptive analgesic effect of dexamethasone and diclofenac following third molar surgery","volume":"27","author":"Simone","year":"2013","journal-title":"Braz Oral Res"},{"key":"B31","doi-asserted-by":"publisher","first-page":"1177","DOI":"10.1016\/0278-2391(92)90149-T","article-title":"Evaluation of dexamethasone for reduction of postsurgical sequelae of third molar removal","volume":"50","author":"Neupert","year":"1992","journal-title":"J Oral Maxillofac Surg"},{"key":"B32","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1093\/bja\/aes431","article-title":"Impact of perioperative dexamethasone on postoperative analgesia and side-effects: systematic review and meta-analysis","volume":"110","author":"Waldron","year":"2013","journal-title":"Br J Anaesth"},{"key":"B33","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1056\/NEJM199201303260501","article-title":"The timing of prophylactic administration of antibiotics and the risk of surgical-wound infection","volume":"326","author":"Classen","year":"1992","journal-title":"N Engl J Med"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.11607\/jomi.5943","article-title":"Single-Dose bioavailability for prophylactic coverage in patients undergoing dental implant surgery","volume":"33","author":"Aravena","year":"2018","journal-title":"Int J Oral Maxillofac Implants"},{"key":"B35","doi-asserted-by":"publisher","first-page":"e612","DOI":"10.4317\/medoral.19778","article-title":"Comparative trial between the use of amoxicillin and amoxicillin clavulanate in the removal of third molars","volume":"19","author":"Iglesias-Mart\u00edn","year":"2014","journal-title":"Medicina Oral Patolog\u00eda Oral y Cirug\u00eda Bucal"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.7860\/JCDR\/2021\/50068.15517","article-title":"Single dose preoperative intravenous antibiotic versus 5 days postoperative per oral antibiotic therapy in third molar surgery-A randomised clinical trial","volume":"15","author":"Sathish","year":"2021","journal-title":"J Clin Diagnostic Res"},{"key":"B37","doi-asserted-by":"publisher","first-page":"104387","DOI":"10.1016\/j.amsu.2022.104387","article-title":"Quality of life after extraction of mandibular wisdom teeth: a systematic review","volume":"81","author":"Hallab","year":"2022","journal-title":"Ann Med Surg"},{"key":"B38","volume-title":"Head, Neck, and Orofacial Infections: An Interdisciplinary Approach","author":"Hupp","year":"2015"},{"key":"B39","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1080\/19424396.2017.12222443","article-title":"Systemic conditions and oral health","volume":"45","author":"Shetty","year":"2017","journal-title":"J Calif Dent Assoc"},{"key":"B40","article-title":"Odontogenic infections of the fascial spaces","volume":"203","author":"Boynton","year":"2015","journal-title":"Head, Neck and Orofacial Infections: An Interdisciplinary Approach E-Book"},{"key":"B41","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1038\/sj.bdj.4806453","article-title":"Factors affecting the onset and severity of pain following the surgical removal of unilateral impacted mandibular third molar teeth","volume":"164","author":"Fisher","year":"1988","journal-title":"Br Dent J"},{"key":"B42","first-page":"6","article-title":"Effective postoperative pain prevention through administration of bupivacaine and diclofenac","volume":"41","author":"Hyrkas","year":"1994","journal-title":"Anesth Prog"},{"key":"B43","volume-title":"WHO Guidelines for the Pharmacological and Radiotherapeutic Management of Cancer Pain in Adults and Adolescents","year":"2018"},{"key":"B44","doi-asserted-by":"publisher","first-page":"1652","DOI":"10.1016\/j.jcms.2019.07.019","article-title":"A randomized anesthethic potency comparison between ropivacaine and bupivacaine on the perioperative regional anesthesia in lower third molar surgery","volume":"47","author":"Tijanic","year":"2019","journal-title":"J Craniomaxillofac Surg"},{"key":"B45","doi-asserted-by":"publisher","first-page":"1916","DOI":"10.3389\/fphar.2020.580289","article-title":"Analgesic effect of Acetaminophen: a review of known and novel mechanisms of action","volume":"11","author":"Ohashi","year":"2020","journal-title":"Front Pharmacol"},{"key":"B46","first-page":"147","author":"McCartney","year":"2020"},{"key":"B47","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1111\/anae.15245","article-title":"Local anaesthetic adjuncts for peripheral regional anaesthesia: a narrative review","volume":"76","author":"Desai","year":"2021","journal-title":"Anaesthesia"},{"key":"B48","doi-asserted-by":"publisher","first-page":"255","DOI":"10.4097\/kja.21390","article-title":"Efficacy of perineural versus intravenous dexamethasone in prolonging the duration of analgesia when administered with peripheral nerve blocks: a systematic review and meta-analysis","volume":"75","author":"Tan","year":"2022","journal-title":"Korean J Anesthesiol"},{"key":"B49","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1016\/j.bja.2017.11.062","article-title":"Co-administration of dexamethasone with peripheral nerve block: intravenous vs perineural application: systematic review, meta-analysis, meta-regression and trial-sequential analysis","volume":"120","author":"Heesen","year":"2018","journal-title":"Br J Anaesth"},{"key":"B50","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1213\/01.ane.0000189055.06729.0a","article-title":"Dexamethasone added to lidocaine prolongs axillary brachial plexus blockade","volume":"102","author":"Movafegh","year":"2006","journal-title":"Anesth Analg"},{"key":"B51","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1016\/j.maxilo.2018.01.001","article-title":"Evaluaci\u00f3n de la eficacia de la administraci\u00f3n peri-operatoria de hidrocortisona y dexametasona para prevenir las complicaciones postoperatorias de la cirug\u00eda oral y maxilofacial","volume":"40","author":"Bhandage","year":"2018","journal-title":"Revista Espa\u00f1ola de Cirug\u00eda Oral y Maxilofacial"},{"key":"B52","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1093\/bja\/aet417","article-title":"Effects of dexamethasone as a local anaesthetic adjuvant for brachial plexus block: a systematic review and meta-analysis of randomized trials","volume":"112","author":"Choi","year":"2014","journal-title":"Br J Anaesth"},{"key":"B53","doi-asserted-by":"publisher","first-page":"200","DOI":"10.1111\/ors.12049","article-title":"Use of dexamethasone to minimise post-operative sequelae after third molar surgery: comparison of five different routes of administration","volume":"6","author":"Majid","year":"2013","journal-title":"Oral Surg"},{"key":"B54","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1111\/j.1834-7819.2011.01312.x","article-title":"Applied anatomy of the pterygomandibular space: improving the success of inferior alveolar nerve blocks","volume":"56","author":"Khoury","year":"2011","journal-title":"Aust Dent J"},{"key":"B55","doi-asserted-by":"publisher","first-page":"1223","DOI":"10.2214\/ajr.165.5.7572508","article-title":"Normal age-related conversion of bone marrow in the mandible: mR imaging findings","volume":"165","author":"Yamada","year":"1995","journal-title":"AJR Am J Roentgenol"},{"key":"B56","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/B978-012340440-4\/50046-5","article-title":"Approaches to novel anti-arthritic drugs by modulation of the arachidonic acid cascade","volume-title":"Mechanisms and Models in Rheumatoid Arthritis","author":"McMillan","year":"1995"},{"key":"B57","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1016\/0022-4731(88)90088-X","article-title":"Glucocorticoid effect on arachidonic acid metabolism in vivo","volume":"30","author":"Naray-Fejes-T\u00f3th","year":"1988","journal-title":"J Steroid Biochem"},{"key":"B58","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1038\/sj.bjp.0706736","article-title":"How corticosteroids control inflammation: quintiles prize lecture 2005","volume":"148","author":"Barnes","year":"2006","journal-title":"Br J Pharmacol"},{"key":"B59","doi-asserted-by":"publisher","first-page":"1035","DOI":"10.1016\/j.bjoms.2022.05.003","article-title":"Comparative efficacy and safety of different corticosteroids to reduce inflammatory complications after mandibular third molar surgery: a systematic review and network meta-analysis","volume":"60","author":"dos Santos Canellas","year":"2022","journal-title":"Br J Oral Maxillofac Surg"},{"key":"B60","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1007\/s10006-016-0564-3","article-title":"High performance liquid chromatography determination of dexamethasone in plasma to evaluate its systemic absorption following intra-space pterygomandibular injection of twin-mix (mixture of 2% lignocaine with 1: 200,000 epinephrine and 4\u2005mg dexamethasone): randomized control trial","volume":"20","author":"Bhargava","year":"2016","journal-title":"Oral Maxillofac Surg"},{"key":"B61","doi-asserted-by":"publisher","first-page":"1105","DOI":"10.1007\/s12325-016-0357-y","article-title":"Do corticosteroids still have a role in the management of third molar surgery?","volume":"33","author":"Ngeow","year":"2016","journal-title":"Adv Ther"},{"key":"B62","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1016\/j.joms.2021.07.013","article-title":"Twin mixed local anesthesia in third molar surgery-randomized controlled trial","volume":"80","author":"Gaur","year":"2022","journal-title":"J Oral Maxillofac Surg"},{"key":"B63","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1016\/j.jobcr.2015.02.001","article-title":"Pre-emptive effect of dexamethasone injection and consumption on post-operative swelling, pain, and trismus after third molar surgery. A prospective, double blind and randomized study","volume":"5","author":"Chaudhary","year":"2015","journal-title":"J Oral Biol Craniofac Res"}],"container-title":["Frontiers in Oral Health"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/froh.2024.1349832\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T05:07:37Z","timestamp":1707455257000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/froh.2024.1349832\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,9]]},"references-count":63,"alternative-id":["10.3389\/froh.2024.1349832"],"URL":"https:\/\/doi.org\/10.3389\/froh.2024.1349832","relation":{},"ISSN":["2673-4842"],"issn-type":[{"value":"2673-4842","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,2,9]]},"article-number":"1349832"}}