{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T18:42:29Z","timestamp":1769798549208,"version":"3.49.0"},"reference-count":37,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T00:00:00Z","timestamp":1769731200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Oral Health"],"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>This study explored associations between dentition status and cardiometabolic diseases in adults.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and methods<\/jats:title>\n                    <jats:p>Cross-sectional analysis was conducted using data from adults receiving routine care at an urban US Dental School clinic between January 1, 2020, and June 1, 2023. Associations between dentition status (measured by tooth loss and functional dentition [FD] status) and cardiometabolic diseases (diabetes mellitus [DM], hypertension [HTN], stroke, and cardiovascular disease [CVD]) were explored using binary logistic regression models while controlling for cardiometabolic risk factors [CMRFs].<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The sample (\n                      <jats:italic>N<\/jats:italic>\n                      \u2009=\u200932,541) was 67.6% 40 years or older, 54.1% female, 51.7% White\/Caucasian, 41.7% Black, 70.3% non-Hispanic\/non-Latino, 69.6% overweight\/obese; 16.0% reported tobacco use. The median number of remaining teeth was 26.0; 75.7% had FD. After adjusting for CMRFs, each additional tooth was associated with lower odds of DM (OR\u2009=\u20090.98, 95% CI\u2009=\u20090.98, 0.99), HTN (OR\u2009=\u20090.98, 95% CI\u2009=\u20090.98, 0.99), stroke (OR\u2009=\u20090.97, 95% CI\u2009=\u20090.96, 0.98), and CVD (OR\u2009=\u20090.97, 95% CI\u2009=\u20090.97,0.98). FD was associated with lower odds of DM (OR\u2009=\u20090.77, 95%CI\u2009=\u20090.70,0.84), HTN (OR\u2009=\u20090.78, 95% CI\u2009=\u20090.72, 0.850), stroke (OR\u2009=\u20090.65, 95% CI\u2009=\u20090.55,0.77), and CVD (OR\u2009=\u20090.71, 95% CI\u2009=\u20090.63\u20130.79). After adjusting for comorbid cardiometabolic conditions, having more teeth remained associated with lower odds of DM (OR\u2009=\u20090.99, 95% CI\u2009=\u20090.98, 0.99), HTN (OR\u2009=\u20090.99, 95% CI\u2009=\u20090.98, 1.00), and CVD (OR\u2009=\u20090.98, 95% CI\u2009=\u20090.97, 0.99). FD was associated with lower odds of DM (OR\u2009=\u20090.82, 95% CI\u2009=\u20090.68\u20130.92), HTN (OR\u2009=\u20090.84, 95% CI\u2009=\u20090.77, 0.92), and CVD (OR\u2009=\u20090.81, 95% CI\u2009=\u20090.71, 0.93).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Tooth retention is associated with lower odds of having cardiometabolic disease. Enhanced knowledge and awareness of these associations can lead to improved cardiometabolic risk screening in interprofessional settings.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/froh.2026.1685373","type":"journal-article","created":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T06:42:34Z","timestamp":1769755354000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Associations between dentition status and cardiometabolic disease in adults: a cross-sectional analysis"],"prefix":"10.3389","volume":"7","author":[{"given":"Rena","family":"Zelig","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew","family":"Swader","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Riva","family":"Touger-Decker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven","family":"Singer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hamed","family":"Samavat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2026,1,30]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"e347","DOI":"10.1161\/CIR.0000000000001209","article-title":"2024 Heart disease and stroke statistics: a report of US and global data from the American heart association","volume":"149","author":"Martin","year":"2024","journal-title":"Circulation"},{"key":"B2","doi-asserted-by":"publisher","first-page":"2361","DOI":"10.1016\/j.jacc.2022.11.005","article-title":"The global burden of cardiovascular diseases and risk: a compass for future health","volume":"80","author":"Vaduganathan","year":"2022","journal-title":"J Am Coll Cariol"},{"key":"B3","doi-asserted-by":"publisher","first-page":"2982","DOI":"10.1016\/j.jacc.2020.11.010","article-title":"Global burden of cardiovascular diseases and risk factors, 1990\u20132019: update from the GBD 2019 study","volume":"76","author":"Roth","year":"2020","journal-title":"J Am Coll Cariol"},{"key":"B4","doi-asserted-by":"publisher","first-page":"e563","DOI":"10.1161\/CIR.0000000000000677","article-title":"2019 ACC\/AHA guideline on the primary prevention of cardiovascular disease: executive summary: a report of the American college of cardiology\/American heart association task force on clinical practice guidelines","volume":"140","author":"Arnett","year":"2019","journal-title":"Circulation"},{"key":"B5","doi-asserted-by":"publisher","first-page":"19","DOI":"10.3390\/jcdd6020019","article-title":"Cardiovascular risks associated with gender and aging","volume":"6","author":"Rodgers","year":"2019","journal-title":"J Cardiovasc Dev Dis"},{"key":"B6","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1177\/2380084420981016","article-title":"Tooth loss and nutritional status in older adults: a systematic review and meta-analysis","volume":"7","author":"Zelig","year":"2022","journal-title":"JDR Clin Trans Res"},{"key":"B7","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1177\/23800844211063859","article-title":"Associations between dentition Status and nutritional Status in community-dwelling older adults","volume":"8","author":"Honeywell","year":"2023","journal-title":"JDR Clin Trans Res"},{"key":"B8","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1136\/jech-2015-206745","article-title":"Periodontitis is an independent risk indicator for atherosclerotic cardiovascular diseases among 60,174 participants in a large dental school in The Netherlands","volume":"71","author":"Beukers","year":"2017","journal-title":"J Epidemiol Community Health"},{"key":"B9","doi-asserted-by":"publisher","first-page":"1027","DOI":"10.1016\/j.adaj.2019.07.023","article-title":"Association between metabolic syndrome and tooth loss: a systematic review and meta-analysis","volume":"150","author":"Souza","year":"2019","journal-title":"J Am Dent Assoc"},{"key":"B10","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1016\/j.adaj.2018.09.010","article-title":"Tooth loss among older adults according to poverty status in the United States from 1999 through 2004 and 2009 through 2014","volume":"150","author":"Dye","year":"2019","journal-title":"J Am Dent Assoc"},{"key":"B11","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.jdent.2017.10.012","article-title":"Does tooth loss affect dietary intake and nutritional status? 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