{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T06:15:44Z","timestamp":1783664144801,"version":"3.55.0"},"reference-count":35,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T00:00:00Z","timestamp":1783641600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Reprod. Health"],"abstract":"\n Background<\/jats:title>\n Male infertility is a growing reproductive health concern in Ghana, contributing significantly to the burden of infertility among couples. Bacteriospermia, the presence of bacteria in semen, has been implicated in male infertility through its potential adverse effects on sperm quality; however, its association with semen parameters remains inconsistent across studies. This study aimed to determine the prevalence of bacteriospermia and examine its association with semen parameters among males attending a fertility clinic in Kumasi, Ghana.<\/jats:p>\n <\/jats:sec>\n \n Materials and methods<\/jats:title>\n Semen samples from 226 males attending a fertility hospital in Kumasi were collected and evaluated according to WHO guidelines. Additionally, samples were cultured for bacteria using standard bacterial culture techniques.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n The prevalence of bacteriospermia was 46.5%, with\n Escherichia coli<\/jats:italic>\n (41.9%),\n Klebsiella<\/jats:italic>\n spp. (25.7%),\n Staphylococcus<\/jats:italic>\n spp. (24.8%),\n Streptococcus<\/jats:italic>\n spp. (2.9%), and\n Bacillus<\/jats:italic>\n spp. (1.9%) identified. Abnormal semen parameters were observed in 47.6% of participants, predominantly teratozoospermia. No significant association was found between bacteriospermia and semen parameters (\n p<\/jats:italic>\n \u2009&gt;\u20090.05), though semen volume approached significance as a predictor of bacteriospermia (\n p<\/jats:italic>\n \u2009=\u20090.057), with hypospermia associated with significantly lower odds of bacteriospermia (aOR\u2009=\u20090.558;\n p<\/jats:italic>\n \u2009=\u20090.047) and hyperspermia showing no significant association (aOR\u2009=\u20090.961;\n p<\/jats:italic>\n \u2009=\u20090.160).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n A high prevalence of bacteriospermia (46.5%) and abnormal semen parameters (47.6%, predominantly teratozoospermia) were observed among men seeking fertility evaluation, with\n E. coli<\/jats:italic>\n as the most frequently isolated organism. No significant association was found between bacteriospermia and semen parameters, though hypospermia was associated with significantly lower odds of bacteriospermia. Routine screening and further research incorporating molecular techniques and larger cohorts are recommended.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.3389\/frph.2026.1853404","type":"journal-article","created":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T05:39:21Z","timestamp":1783661961000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Prevalence of bacteriospermia and its association with semen parameters among men attending a fertility clinic in Kumasi, Ghana"],"prefix":"10.3389","volume":"8","author":[{"given":"Evans","family":"Anokye Kumi","sequence":"first","affiliation":[{"name":"Department of Theoretical and Applied Biology, Kwame Nkrumah University of Science and Technology","place":["Kumasi, Ghana"]},{"name":"Department of Nursing, Valley View University","place":["Kumasi, Ghana"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor Boachie","family":"Owusu","sequence":"additional","affiliation":[{"name":"Department of Physiology, School of Medicine and Dentistry, Kwame Nkrumah University of Science and Technology","place":["Kumasi, Ghana"]},{"name":"Oak Specialist Hospital","place":["Kumasi, Ghana"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ebenezer Kojo","family":"Addae","sequence":"additional","affiliation":[{"name":"Department of Physiology, School of Medicine and Dentistry, Kwame Nkrumah University of Science and Technology","place":["Kumasi, Ghana"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter Nyarko","family":"Coffie","sequence":"additional","affiliation":[{"name":"Department of Theoretical and Applied Biology, Kwame Nkrumah University of Science and Technology","place":["Kumasi, Ghana"]},{"name":"Department of Physiology, Accra College of Medicine","place":["Accra, Ghana"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Darko","sequence":"additional","affiliation":[{"name":"Department of Clinical Microbiology, Kwame Nkrumah University of Science and Technology","place":["Kumasi, Ghana"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rex Kwadwo Mawuli","family":"Djokoto","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Komfo Anokye Teaching Hospital, Kwame Nkrumah University of Science and Technology","place":["Kumasi, Ghana"]},{"name":"Oak Specialist Hospital","place":["Kumasi, Ghana"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kweku","family":"Bedu-Addo","sequence":"additional","affiliation":[{"name":"Department of Physiology, School of Medicine and Dentistry, Kwame Nkrumah University of Science and Technology","place":["Kumasi, Ghana"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John 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