{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T06:31:18Z","timestamp":1787725878518,"version":"build-2784847793"},"reference-count":62,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T00:00:00Z","timestamp":1787702400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Reprod. Health"],"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Exposure to radiofrequency electromagnetic radiation (RF-EMR) has been linked in several studies to male reproductive dysfunction, with oxidative stress and sperm DNA damage proposed as key underlying mechanisms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      The present study evaluated the protective effect of Swadamshtradi rasayana (SDR) against RF-EMR\u2013induced sperm alterations in mice. Twenty-four Swiss albino mice were allocated into four groups: control, RF-EMR\u2013exposed, RF-EMR with Swadamshtradi rasayana (729 mg\/kg, orally), and RF-EMR with\n                      <jats:italic>\u03b1<\/jats:italic>\n                      -tocopherol (32.4 mg\/kg, orally). Animals were exposed to RF-EMR (900\u20131800MHz) for 3 h\/day for 35 days, and sperm count, viability, reactive oxygen species levels, antioxidant enzyme activity, lipid peroxidation, and DNA fragmentation were assessed.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      RF-EMR exposure was associated with a significant reduction in sperm count and viability and a significant increase in ROS levels, lipid peroxidation, and DNA fragmentation (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&amp;lt;\u20090.0001 compared with control). Administration of Swadamshtradi rasayana significantly improved sperm parameters and attenuated oxidative stress compared with the RF-EMR\u2013exposed group (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&amp;lt;\u20090.0001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>These findings suggest that Swadamshtradi rasayana may mitigate RF-EMR-induced oxidative stress and associated sperm damage. The observed protective effects are consistent with the reported antioxidant properties of its constituent herbs.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/frph.2026.1912688","type":"journal-article","created":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T06:02:28Z","timestamp":1787724148000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Swadamshtradi rasayana attenuates radiofrequency radiation-induced oxidative stress and improves sperm parameters in Swiss albino mice"],"prefix":"10.3389","volume":"8","author":[{"given":"Vahab Rahimkutty","family":"Abdul","sequence":"first","affiliation":[{"name":"Department of Swasthavritta (Social and Preventive Medicine), Amrita School of Ayurveda, Amritapuri, Amrita Vishwa Vidyapeetham","place":["Kollam, 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