{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T14:08:23Z","timestamp":1789135703620,"version":"build-2803163510"},"reference-count":228,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T00:00:00Z","timestamp":1789084800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Sleep"],"abstract":"<jats:p>\n                    Obesity and sleep disturbances are highly prevalent chronic conditions that share multiple pathophysiological mechanisms, including chronic low-grade inflammation, neuroendocrine dysfunction, circadian misalignment, autonomic imbalance, insulin resistance, and metabolic dysregulation. These conditions establish a multidirectional relationship that contributes to the development and progression of cardiometabolic, respiratory, and psychological comorbidities. In this context, physical exercise (PE) is widely recognized as a non-pharmacological strategy for the prevention and treatment of obesity and sleep disturbances that simultaneously modulates these interconnected pathways while enhancing metabolic flexibility. Growing evidence also supports its role as a non-photic\n                    <jats:italic>zeitgeber<\/jats:italic>\n                    that synchronizes central and peripheral biological clocks, modulates clock gene expression, and influences metabolic responses according to the time of day it is performed. Through these multisystem adaptations, PE may interrupt the vicious cycle linking obesity and sleep disturbances, thereby improving metabolic health and reducing the burden of obesity-related comorbidities. This review discusses how PE modulates the multidirectional relationship between sleep and obesity through integrated multisystem adaptations, highlighting its potential to improve both sleep and overall health.\n                  <\/jats:p>","DOI":"10.3389\/frsle.2026.1943600","type":"journal-article","created":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T13:27:08Z","timestamp":1789133228000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Physical exercise as a modulator of the sleep\u2013obesity interaction: metabolic, neuroendocrine and circadian mechanisms"],"prefix":"10.3389","volume":"5","author":[{"given":"Raquel M. S.","family":"Campos","sequence":"first","affiliation":[{"name":"Programa de P\u00f3s-Gradua\u00e7\u00e3o Interdisciplinar em Ci\u00eancias da Sa\u00fade, Universidade Federal de S\u00e3o Paulo","place":["Santos, Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helton","family":"de S\u00e1 Souza","sequence":"additional","affiliation":[{"name":"Departamento de Educa\u00e7\u00e3o F\u00edsica, Universidade Federal de Vi\u00e7osa","place":["Vi\u00e7osa, MG, Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina Machado","family":"Favaron","sequence":"additional","affiliation":[{"name":"Programa de P\u00f3s-Gradua\u00e7\u00e3o Interdisciplinar em Ci\u00eancias da Sa\u00fade, Universidade Federal de S\u00e3o Paulo","place":["Santos, Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guilherme Pereira","family":"Saborosa","sequence":"additional","affiliation":[{"name":"Departamento de Educa\u00e7\u00e3o F\u00edsica, Universidade Federal de Vi\u00e7osa","place":["Vi\u00e7osa, MG, Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luciana Cervi","family":"Ferez","sequence":"additional","affiliation":[{"name":"Departamento de Psicobiologia, Universidade Federal de S\u00e3o Paulo","place":["S\u00e3o Paulo, Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio","family":"Tufik","sequence":"additional","affiliation":[{"name":"Departamento de Psicobiologia, Universidade Federal de S\u00e3o Paulo","place":["S\u00e3o Paulo, Brazil"]},{"name":"Instituto do Sono \u2013 Associa\u00e7\u00e3o Fundo de Incentivo \u00e0 Pesquisa (AFIP)","place":["S\u00e3o Paulo, SP, Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanna Karen Moreira","family":"Antunes","sequence":"additional","affiliation":[{"name":"Programa de P\u00f3s-Gradua\u00e7\u00e3o Interdisciplinar em Ci\u00eancias da Sa\u00fade, Universidade Federal de S\u00e3o Paulo","place":["Santos, Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V\u00e2nia","family":"D'Almeida","sequence":"additional","affiliation":[{"name":"Departamento de Psicobiologia, Universidade Federal de S\u00e3o Paulo","place":["S\u00e3o Paulo, Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcos","family":"M\u00f4nico-Neto","sequence":"additional","affiliation":[{"name":"Programa de P\u00f3s-Gradua\u00e7\u00e3o Interdisciplinar em Ci\u00eancias da Sa\u00fade, Universidade Federal de S\u00e3o Paulo","place":["Santos, Brazil"]},{"name":"Departamento de Psicobiologia, Universidade Federal de S\u00e3o Paulo","place":["S\u00e3o Paulo, Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,9,11]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"2198","DOI":"10.4314\/ahs.v19i2.45","article-title":"Aerobic exercise modulates cytokine profile and sleep quality in elderly","volume":"19","author":"Abd El-Kader","year":"2019","journal-title":"Afr. Health Sci"},{"key":"B2","doi-asserted-by":"publisher","first-page":"E105","DOI":"10.1002\/oby.20083","article-title":"Cortisol, obesity, and the metabolic syndrome: a cross-sectional study of obese subjects and review of the literature","volume":"21","author":"Abraham","year":"2013","journal-title":"Obesity"},{"key":"B3","doi-asserted-by":"publisher","first-page":"1153","DOI":"10.3109\/07420528.2012.719971","article-title":"Circadian typology: a comprehensive review","volume":"29","author":"Adan","year":"2012","journal-title":"Chronobiol. Int"},{"key":"B4","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1016\/j.rmed.2016.05.015","article-title":"Effect of exercise training on sleep apnea: a systematic review and meta-analysis. Respir","volume":"116","author":"Aiello","year":"2016","journal-title":"Med"},{"key":"B5","doi-asserted-by":"publisher","first-page":"1994","DOI":"10.3390\/biomedicines12091994","article-title":"Factors associated with the development of depression and the influence of obesity on depressive disorders: a narrative review","volume":"12","author":"Alberti","year":"2024","journal-title":"Biomedicines"},{"key":"B6","doi-asserted-by":"publisher","first-page":"481","DOI":"10.3390\/nu13020481","article-title":"Gut hormones in health and obesity: the upcoming role of short-chain fatty acids","volume":"13","author":"Alhabeeb","year":"2021","journal-title":"Nutrients"},{"key":"B7","doi-asserted-by":"publisher","first-page":"e17525","DOI":"10.7717\/peerj.17525","article-title":"Effects of combined aerobic and resistance training on glycemic control, blood pressure, inflammation, cardiorespiratory fitness and quality of life in patients with type 2 diabetes and overweight\/obesity: a systematic review and meta-analysis","volume":"12","author":"Al-Mhanna","year":"2024","journal-title":"PeerJ"},{"key":"B8","doi-asserted-by":"publisher","first-page":"e43595","DOI":"10.7759\/cureus.43595","article-title":"The effect of physical activity on sleep quality and sleep disorder: a systematic review","volume":"15","author":"Alnawwar","year":"2023","journal-title":"Cureus"},{"key":"B9","doi-asserted-by":"publisher","first-page":"e62465","DOI":"10.7759\/cureus.62465","article-title":"Effects of exercise training on heart rate variability in healthy adults: a systematic review and meta-analysis of randomized controlled trials","volume":"16","author":"Amekran","year":"2024","journal-title":"Cureus"},{"key":"B10","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1007\/s40211-019-0302-9","article-title":"Obesity and anxiety symptoms: a systematic review and meta-analysis","volume":"33","author":"Amiri","year":"2019","journal-title":"Neuropsychiatry"},{"key":"B11","doi-asserted-by":"publisher","first-page":"bvae165","DOI":"10.1210\/jendso\/bvae165","article-title":"The impact of exercise intensity and sex on endogenous ghrelin levels and appetite in healthy humans","volume":"8","author":"Anderson","year":"2024","journal-title":"J. Endocr. Soc"},{"key":"B12","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1111\/sjop.12685","article-title":"Emotional eating: a treatment-worthy construct, or artifact of relations between mood and eating behaviors in younger and older women with obesity. Scand. J","volume":"62","author":"Annesi","year":"2021","journal-title":"Psychol"},{"key":"B13","doi-asserted-by":"publisher","first-page":"e13664","DOI":"10.1111\/obr.13664","article-title":"Social jetlag and obesity: a systematic review and meta-analysis","volume":"25","author":"Arab","year":"2024","journal-title":"Obesity Rev"},{"key":"B14","doi-asserted-by":"publisher","first-page":"1553","DOI":"10.5665\/sleep.3056","article-title":"Effectiveness of lifestyle interventions on obstructive sleep apnea (OSA): systematic review and meta-analysis","volume":"36","author":"Araghi","year":"","journal-title":"Sleep"},{"key":"B15","doi-asserted-by":"publisher","first-page":"1859","DOI":"10.5665\/sleep.3216","article-title":"The complex associations among sleep quality, anxiety-depression, and quality of life in patients with extreme obesity","volume":"36","author":"Araghi","year":"","journal-title":"Sleep"},{"key":"B16","doi-asserted-by":"publisher","first-page":"e70167","DOI":"10.14814\/phy2.70167","article-title":"Acute effect of exercise on appetite-related factors in males with obesity: a pilot study","volume":"12","author":"Asri","year":"2024","journal-title":"Physiol. Rep"},{"key":"B17","doi-asserted-by":"publisher","first-page":"331","DOI":"10.1007\/s00421-006-0361-z","article-title":"Exercise as a synchroniser of human circadian rhythms: an update and discussion of the methodological problems. Eur. J. Appl","volume":"99","author":"Atkinson","year":"2007","journal-title":"Physiol"},{"key":"B18","doi-asserted-by":"publisher","first-page":"b3868","DOI":"10.1136\/bmj.b3868","article-title":"Obesity and depression or anxiety","volume":"339","author":"Atlantis","year":"2009","journal-title":"BMJ"},{"key":"B19","doi-asserted-by":"publisher","first-page":"5984","DOI":"10.3390\/jcm14175984","article-title":"Gender differences in the perceived impact of major depressive disorder on quality of life: a cross-sectional population study","volume":"14","author":"Aviles Gonzalez","year":"2025","journal-title":"J. Clin. Med"},{"key":"B20","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1007\/s11332-022-00963-8","article-title":"Evening chronotype predicts dropout of physical exercise: a prospective analysis","volume":"19","author":"Back","year":"2023","journal-title":"Sport Sci. Health"},{"key":"B21","doi-asserted-by":"publisher","first-page":"e0253114","DOI":"10.1371\/journal.pone.0253114","article-title":"Physical activity motives, barriers, and preferences in people with obesity: a systematic review","volume":"16","author":"Baillot","year":"2021","journal-title":"PLoS One"},{"key":"B22","doi-asserted-by":"publisher","first-page":"139","DOI":"10.3109\/09540261.2014.911149","article-title":"Circadian misalignment and health","volume":"26","author":"Baron","year":"2014","journal-title":"Int. Rev. Psychiatry"},{"key":"B23","doi-asserted-by":"publisher","first-page":"1349","DOI":"10.1126\/science.1195027","article-title":"Circadian integration of metabolism and energetics","volume":"330","author":"Bass","year":"2010","journal-title":"Science"},{"key":"B24","doi-asserted-by":"publisher","first-page":"987208","DOI":"10.3389\/fendo.2023.987208","article-title":"Enhancing the metabolic benefits of exercise: is timing the key?","volume":"14","author":"Bennett","year":"2023","journal-title":"Front. Endocrinol."},{"key":"B25","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1002\/oby.23078","article-title":"Effect of aerobic exercise intensity on energy expenditure and weight loss in severe obesity: a randomized controlled trial","volume":"29","author":"Berge","year":"2021","journal-title":"Obesity"},{"key":"B26","doi-asserted-by":"publisher","first-page":"2599","DOI":"10.1249\/MSS.0000000000003795","article-title":"Physical activity and exercise intensity terminology: a joint American College of Sports Medicine (ACSM) expert statement and Exercise and Sport Science Australia (ESSA) consensus statement. Med. Sci","volume":"57","author":"Bishop","year":"2025","journal-title":"Sports Exerc"},{"key":"B27","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1111\/dom.16263","article-title":"An overview of obesity-related complications: the epidemiological evidence linking body weight and other markers of obesity to adverse health outcomes","volume":"27","author":"Bl\u00fcher","year":"2025","journal-title":"Diabetes Obes. Metab"},{"key":"B28","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1016\/j.jadohealth.2009.06.018","article-title":"High exercise levels are related to favorable sleep patterns and psychological functioning in adolescents: a comparison of athletes and controls. J. Adolesc","volume":"46","author":"Brand","year":"2010","journal-title":"Health"},{"key":"B29","doi-asserted-by":"publisher","first-page":"2428","DOI":"10.3390\/nu12082428","article-title":"Diet, stress and mental health","volume":"12","author":"Bremner","year":"2020","journal-title":"Nutrients"},{"key":"B30","doi-asserted-by":"publisher","first-page":"490","DOI":"10.1249\/MSS.0000000000001930","article-title":"Individual response to standardized exercise: total and abdominal adipose tissue","volume":"52","author":"Brennan","year":"2019","journal-title":"Med. Sci. Sports Exerc"},{"key":"B31","doi-asserted-by":"publisher","first-page":"R29","DOI":"10.1152\/ajpregu.90706.2008","article-title":"Influence of resistance and aerobic exercise on hunger, circulating levels of acylated ghrelin, and peptide YY in healthy males. Am. J. Physiol. Regul. Integr. Comp","volume":"296","author":"Broom","year":"2009","journal-title":"Physiol"},{"key":"B32","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1186\/s40798-023-00577-5","article-title":"Best time of day for strength and endurance training to improve health and performance? A systematic review with meta-analysis","volume":"9","author":"Bruggisser","year":"2023","journal-title":"Sports Med. Open"},{"key":"B33","doi-asserted-by":"publisher","first-page":"1451","DOI":"10.1136\/bjsports-2020-102955","article-title":"World Health Organization 2020 guidelines on physical activity and sedentary behaviour","volume":"54","author":"Bull","year":"2020","journal-title":"Br. J. Sports Med"},{"key":"B34","doi-asserted-by":"publisher","first-page":"2217","DOI":"10.2337\/dc12-2467","article-title":"Large pre- and postexercise rapid-acting insulin reductions preserve glycemia and prevent early- but not late-onset hypoglycemia in patients with type 1 diabetes","volume":"38","author":"Campbell","year":"2015","journal-title":"Diabetes Care"},{"key":"B35","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1016\/j.appet.2013.05.018","article-title":"Aerobic training is more effective than aerobic plus resistance training to improve anorexigenic\/orexigenic factors in obese adolescents","volume":"69","author":"Carnier","year":"2013","journal-title":"Appetite"},{"key":"B36","doi-asserted-by":"publisher","first-page":"784","DOI":"10.1111\/j.1742-1241.2009.02306.x","article-title":"The role of orexigenic and anorexigenic factors in an interdisciplinary weight loss therapy for obese adolescents with symptoms of eating disorders","volume":"64","author":"Carnier","year":"2010","journal-title":"Int. J. Clin. Pract"},{"key":"B37","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1159\/000139148","article-title":"Hormonal alteration in obese adolescents with eating disorder: effects of multidisciplinary therapy","volume":"70","author":"Carnier","year":"2008","journal-title":"Horm. Res"},{"key":"B38","doi-asserted-by":"publisher","first-page":"855107","DOI":"10.3389\/fnsys.2022.855107","article-title":"Effects of exercise on the sleep microarchitecture in the aging brain: a study on a sedentary sample. Front. Syst","volume":"16","author":"Cassim","year":"2022","journal-title":"Neurosci"},{"key":"B39","doi-asserted-by":"publisher","first-page":"101264","DOI":"10.1016\/j.yfrne.2026.101264","article-title":"Sleep, circadian rhythms and eating disorders: a systematic review","volume":"82","author":"Cera","year":"2026","journal-title":"Front. Neuroendocrinol"},{"key":"B40","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1038\/s41574-022-00747-7","article-title":"The role of insufficient sleep and circadian misalignment in obesity. Nat. Rev","volume":"19","author":"Chaput","year":"2023","journal-title":"Endocrinol"},{"key":"B41","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/healthcare7010001","article-title":"The global problem of insufficient sleep and its serious public health implications","volume":"7","author":"Chattu","year":"2018","journal-title":"Healthcare"},{"key":"B42","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1016\/j.smrv.2014.06.008","article-title":"Sleep and exercise: a reciprocal issue?","volume":"20","author":"Chennaoui","year":"2015","journal-title":"Sleep Med. Rev."},{"key":"B43","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1016\/j.metabol.2018.09.005","article-title":"The epidemiology of obesity","volume":"92","author":"Chooi","year":"2019","journal-title":"Metabolism"},{"key":"B44","doi-asserted-by":"publisher","first-page":"1984","DOI":"10.1519\/JSC.0b013e31825770a7","article-title":"The effect of training at a specific time of day: a review. J. Strength Cond","volume":"26","author":"Chtourou","year":"2012","journal-title":"Res"},{"key":"B45","doi-asserted-by":"publisher","first-page":"100835","DOI":"10.1016\/j.cophys.2025.100835","article-title":"From clock genes to exercise: shaping the field of exercise chronophysiology","volume":"45","author":"Ciorciari","year":"2025","journal-title":"Curr. Opin. Physiol"},{"key":"B46","doi-asserted-by":"publisher","first-page":"e70057","DOI":"10.1111\/jpi.70057","article-title":"Exercise as a synchronizer: effects on circadian re-entrainment of core body temperature and metabolism following light-dark cycle inversion in mice","volume":"77","author":"Ciorciari","year":"2025","journal-title":"J. Pineal Res"},{"key":"B47","doi-asserted-by":"publisher","first-page":"990","DOI":"10.1210\/er.2018-00084","article-title":"Melatonin as a hormone: new physiological and clinical insights","volume":"39","author":"Cipolla-Neto","year":"2018","journal-title":"Endocr. Rev"},{"key":"B48","doi-asserted-by":"publisher","first-page":"e2517268","DOI":"10.1001\/jamanetworkopen.2025.17268","article-title":"Time-restricted eating and sleep, mood, and quality of life in adults with overweight or obesity: a secondary analysis of a randomized clinical trial","volume":"8","author":"Clavero-Jimeno","year":"2025","journal-title":"JAMA Netw. Open"},{"key":"B49","doi-asserted-by":"publisher","first-page":"1739588","DOI":"10.3389\/fspor.2026.1739588","article-title":"Bidirectional effects of physical activity and sleep on health: evidence and future directions","volume":"8","author":"Clemente-Su\u00e1rez","year":"2026","journal-title":"Front. Sports Act Living"},{"key":"B50","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1016\/j.sleep.2022.10.018","article-title":"Associations between sleep-related heart rate variability and both sleep and symptoms of depression and anxiety: a systematic review","volume":"101","author":"Correia","year":"2023","journal-title":"Sleep Med"},{"key":"B51","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1186\/s12966-025-01754-3","article-title":"Effect of physical activity on changes in weight and aerobic capacity during an 18-month behavioral weight loss intervention. Int. J. Behav. Nutr. Phys","volume":"22","author":"Creasy","year":"2025","journal-title":"Act"},{"key":"B52","doi-asserted-by":"publisher","first-page":"1603595","DOI":"10.3389\/fpsyt.2025.1603595","article-title":"Chrononutrition interventions for mental health: addressing atypical depression, ultra-processed food use disorder, and circadian dysregulation","volume":"16","author":"Cuaranta","year":"2026","journal-title":"Front. Psychiatry"},{"key":"B53","doi-asserted-by":"publisher","first-page":"e13615","DOI":"10.1111\/obr.13615","article-title":"Correlates of physical activity and sedentary behavior in adults living with overweight and obesity: a systematic review","volume":"24","author":"Curran","year":"2023","journal-title":"Obes Rev"},{"key":"B54","doi-asserted-by":"publisher","first-page":"831","DOI":"10.23736\/S0022-4707.16.06235-6","article-title":"Homeostasis model assessment-adiponectin: the role of different types of physical exercise in obese adolescents","volume":"57","author":"da Silveira Campos","year":"2017","journal-title":"J. Sports Med. Phys. Fitness"},{"key":"B55","doi-asserted-by":"publisher","first-page":"1173","DOI":"10.3390\/nu15051173","article-title":"The association of emotional eating with overweight\/obesity, depression, anxiety\/stress, and dietary patterns: a review of the current clinical evidence","volume":"15","author":"Dakanalis","year":"2023","journal-title":"Nutrients"},{"key":"B56","doi-asserted-by":"publisher","first-page":"e70093","DOI":"10.1111\/obr.70093","article-title":"Multidisciplinary therapy to target obesity and its complications in adult population: a narrative review","volume":"27","author":"D\u00e2maso","year":"2026","journal-title":"Obes. Rev"},{"key":"B57","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1111\/nyas.15251","article-title":"Effects of multidisciplinary therapy on energy balance, inflammation, and metabolic diseases in adolescents with obesity: a narrative review","volume":"1542","author":"D\u00e2maso","year":"2024","journal-title":"Ann. N. Y. Acad. Sci"},{"key":"B58","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1590\/1516-4446-2018-0030","article-title":"Effects of resistance exercise training and stretching on chronic insomnia","volume":"41","author":"D'Aurea","year":"2019","journal-title":"Rev. Bras. Psiquiatr"},{"key":"B59","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1007\/s40618-014-0176-4","article-title":"Interleukin-6, soluble interleukin-6 receptor\/interleukin-6 complex and insulin resistance in obese children and adolescents","volume":"38","author":"De Filippo","year":"2015","journal-title":"J. Endocrinol. Invest"},{"key":"B60","doi-asserted-by":"publisher","first-page":"105843","DOI":"10.1016\/j.psyneuen.2022.105843","article-title":"The effects of physical activity on cortisol and sleep: a systematic review and meta-analysis","volume":"143","author":"De Nys","year":"2022","journal-title":"Psychoneuroendocrinology"},{"key":"B61","doi-asserted-by":"publisher","first-page":"3383","DOI":"10.3390\/nu16193383","article-title":"Depression and obesity: do we know everything about it? A narrative review","volume":"16","author":"Debski","year":"2024","journal-title":"Nutrients"},{"key":"B62","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1186\/s12966-023-01424-2","article-title":"Barriers and facilitators to adherence to diet, physical activity, and lifestyle behavior interventions: a qualitative systematic review of the literature","volume":"20","author":"Deslippe","year":"2023","journal-title":"Int. J. Behav. Nutr. Phys. Act"},{"key":"B63","doi-asserted-by":"publisher","first-page":"906","DOI":"10.1016\/j.sleep.2013.09.023","article-title":"A comprehensive rehabilitation program improves disease severity in patients with obstructive sleep apnea syndrome: a pilot randomized controlled study","volume":"15","author":"Desplan","year":"2014","journal-title":"Sleep Med"},{"key":"B64","doi-asserted-by":"publisher","first-page":"996","DOI":"10.1152\/japplphysiol.00632.2023","article-title":"Social jet lag impairs exercise volume and attenuates physiological and metabolic adaptations to voluntary exercise training","volume":"136","author":"Dial","year":"2024","journal-title":"J. Appl. Physiol."},{"key":"B65","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1249\/MSS.0b013e3181949333","article-title":"American College of Sports Medicine position stand. Appropriate physical activity intervention strategies for weight loss and prevention of weight regain for adults","volume":"41","author":"Donnelly","year":"2009","journal-title":"Med. Sci. Sports Exerc"},{"key":"B66","doi-asserted-by":"publisher","first-page":"1499984","DOI":"10.3389\/fnut.2024.1499984","article-title":"The research progress and prospects of circadian rhythm in obesity: a bibliometric analysis","volume":"11","author":"Dou","year":"2025","journal-title":"Front. Nutr"},{"key":"B67","doi-asserted-by":"publisher","first-page":"e2005886","DOI":"10.1371\/journal.pbio.2005886","article-title":"Transcriptional programming of lipid and amino acid metabolism by the skeletal muscle circadian clock","volume":"16","author":"Dyar","year":"2018","journal-title":"PLoS Biol"},{"key":"B68","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1186\/s12955-025-02355-1","article-title":"Fatigue is distinct from sleepiness and negatively impacts individuals living with obstructive sleep apnea (OSA): results from qualitative research of individuals with OSA","volume":"23","author":"Emsellem","year":"2025","journal-title":"Health Qual. Life Outcomes"},{"key":"B69","doi-asserted-by":"publisher","first-page":"104014","DOI":"10.1016\/j.numecd.2025.104014","article-title":"Obesity and sleep disorders: a bidirectional relationship","volume":"35","author":"Figorilli","year":"2025","journal-title":"Nutr. Metab. Cardiovasc. Dis"},{"key":"B70","doi-asserted-by":"publisher","first-page":"122229","DOI":"10.1016\/j.jad.2026.122229","article-title":"Meal Timing Jetlag is associated with anxiety, depressive and insomnia symptoms in a French-speaking online cohort: a cross-sectional analysis of ALIMENTAL 2","volume":"413","author":"Fond","year":"2026","journal-title":"J. Affect. Disord"},{"key":"B71","doi-asserted-by":"publisher","first-page":"1830","DOI":"10.3390\/nu18111830","article-title":"Emotional eating under negative affect: a narrative review from the perspectives of emotion regulation and reward processes in food choice","volume":"18","author":"Fu","year":"2026","journal-title":"Nutrients"},{"key":"B72","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1038\/s41574-018-0150-x","article-title":"Circadian rhythms and exercise: re-setting the clock in metabolic disease. Nat. Rev","volume":"15","author":"Gabriel","year":"2019","journal-title":"Endocrinol"},{"key":"B73","doi-asserted-by":"publisher","first-page":"11256","DOI":"10.1038\/s41598-023-37921-4","article-title":"Sleep quality is a predictor of muscle mass, strength, quality of life, anxiety and depression in older adults with obesity. Sci","volume":"13","author":"Genario","year":"2023","journal-title":"Rep"},{"key":"B74","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/B978-0-12-407703-4.00001-3","article-title":"Diverse roles for MAPK signaling in circadian clocks","volume":"84","author":"Goldsmith","year":"2013","journal-title":"Adv. Genet"},{"key":"B75","doi-asserted-by":"publisher","first-page":"103","DOI":"10.11606\/S1518-8787.2019053001119","article-title":"Adiposity, depression and anxiety: interrelationship and possible mediators. Rev","volume":"53","author":"Gomes","year":"2019","journal-title":"Saude Publica"},{"key":"B76","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1016\/j.artere.2017.10.001","article-title":"Review and analysis of physical exercise at hormonal and brain level, and its influence on appetite","volume":"29","author":"G\u00f3mez Escribano","year":"2017","journal-title":"Clin. Investig. Arterioscler"},{"key":"B77","doi-asserted-by":"publisher","first-page":"426","DOI":"10.1249\/MSS.0000000000001805","article-title":"Exercise training increases metaboreflex control in patients with obstructive sleep apnea","volume":"51","author":"Guerra","year":"2019","journal-title":"Med. Sci. Sports Exerc"},{"key":"B78","doi-asserted-by":"publisher","first-page":"188","DOI":"10.5935\/1984-0063.20220040","article-title":"A clinical trial to compare the effects of aerobic training and resistance training on sleep quality and quality of life in older adults with sleep disturbance","volume":"15","author":"Gupta","year":"2022","journal-title":"Sleep Sci"},{"key":"B79","doi-asserted-by":"publisher","first-page":"643","DOI":"10.1016\/j.coph.2007.10.006","article-title":"Leptin regulation of neuronal excitability and cognitive function","volume":"7","author":"Harvey","year":"2007","journal-title":"Curr. Opin. Pharmacol"},{"key":"B80","doi-asserted-by":"publisher","first-page":"738","DOI":"10.1016\/j.cell.2014.10.029","article-title":"Integrative biology of exercise","volume":"159","author":"Hawley","year":"2014","journal-title":"Cell"},{"key":"B81","doi-asserted-by":"publisher","first-page":"732243","DOI":"10.3389\/fnetp.2021.732243","article-title":"Circadian synchrony: sleep, nutrition, and physical activity. Front. Netw","volume":"1","author":"Healy","year":"2021","journal-title":"Physiol"},{"key":"B82","doi-asserted-by":"publisher","first-page":"1601","DOI":"10.3390\/biomedicines14071601","article-title":"Chrono-exercise medicine: why biological timing matters for human health","volume":"14","author":"Hesketh","year":"2026","journal-title":"Biomedicines"},{"key":"B83","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1186\/s13395-015-0039-5","article-title":"The endogenous molecular clock orchestrates the temporal separation of substrate metabolism in skeletal muscle. Skelet","volume":"5","author":"Hodge","year":"2015","journal-title":"Muscle"},{"key":"B84","doi-asserted-by":"publisher","first-page":"860","DOI":"10.1038\/nature05485","article-title":"Inflammation and metabolic disorders","volume":"444","author":"Hotamisligil","year":"2006","journal-title":"Nature"},{"key":"B85","doi-asserted-by":"publisher","first-page":"114640","DOI":"10.1016\/j.bcp.2021.114640","article-title":"Hypothalamus-skeletal muscle crosstalk during exercise and its role in metabolism modulation. Biochem","volume":"190","author":"Ibeas","year":"2021","journal-title":"Pharmacol"},{"key":"B86","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1007\/s00408-013-9511-3","article-title":"Effects of exercise training on sleep apnea: a meta-analysis","volume":"192","author":"Iftikhar","year":"2014","journal-title":"Lung"},{"key":"B87","doi-asserted-by":"publisher","first-page":"2076","DOI":"10.1249\/MSS.0000000000003520","article-title":"Physical activity and excess body weight and adiposity for adults: American College of Sports Medicine consensus statement. Med. Sci","volume":"56","author":"Jakicic","year":"2024","journal-title":"Sports Exerc"},{"key":"B88","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.orcp.2016.07.003","article-title":"The interface of depression and obesity","volume":"11","author":"Jantaratnotai","year":"2017","journal-title":"Obes. Res. Clin. Pract"},{"key":"B89","doi-asserted-by":"publisher","first-page":"4099","DOI":"10.1038\/s41598-026-36045-9","article-title":"Effect of exercise on hormonal responses in adolescents with obesity and leptin resistance: a randomized trial. Sci","volume":"16","author":"Jeong","year":"2026","journal-title":"Rep"},{"key":"B90","doi-asserted-by":"publisher","first-page":"1425","DOI":"10.2174\/0118715273291985240430074053","article-title":"Obesity and depression: common link and possible targets. CNS Neurol. Disord","volume":"23","author":"Jitte","year":"2024","journal-title":"Drug Targets"},{"key":"B91","doi-asserted-by":"publisher","first-page":"736","DOI":"10.1016\/S0140-6736(13)60734-5","article-title":"Adult obstructive sleep apnoea","volume":"383","author":"Jordan","year":"2014","journal-title":"Lancet"},{"key":"B92","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1016\/j.cmet.2017.06.002","article-title":"CRY1\/2 selectively repress PPAR\u03b4 and limit exercise capacity","volume":"26","author":"Jordan","year":"2017","journal-title":"Cell Metabol."},{"key":"B93","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1007\/s12272-013-0020-y","article-title":"Molecular mechanisms of central leptin resistance in obesity. Arch. Pharm","volume":"36","author":"Jung","year":"2013","journal-title":"Res"},{"key":"B94","doi-asserted-by":"publisher","first-page":"C375","DOI":"10.1152\/ajpcell.00379.2020","article-title":"Adipose tissue inflammation and metabolic dysfunction in obesity","volume":"320","author":"Kawai","year":"2021","journal-title":"Am. J. Physiol. Cell Physiol"},{"key":"B95","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1016\/j.smhs.2022.11.003","article-title":"Chrono-exercise: time-of-day-dependent physiological responses to exercise","volume":"5","author":"Kim","year":"2023","journal-title":"Sports Med. Health Sci"},{"key":"B96","doi-asserted-by":"publisher","first-page":"1610","DOI":"10.1016\/j.ijcard.2012.04.108","article-title":"Blunted heart rate recovery is improved following exercise training in overweight adults with obstructive sleep apnea","volume":"167","author":"Kline","year":"2013","journal-title":"Int. J. Cardiol"},{"key":"B97","doi-asserted-by":"publisher","first-page":"e772","DOI":"10.1002\/osp4.772","article-title":"Short sleep duration is associated with higher risk of central obesity in adults: a systematic review and meta-analysis of prospective cohort studies. Obes. Sci","volume":"10","author":"Kohanmoo","year":"2024","journal-title":"Pract"},{"key":"B98","doi-asserted-by":"publisher","first-page":"1649549","DOI":"10.3389\/fspor.2026.1649549","article-title":"Practical guidelines for exercise prescription in different clinical populations","volume":"8","author":"Komici","year":"2026","journal-title":"Front. Sports Act Living"},{"key":"B99","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1016\/j.smrv.2017.07.002","article-title":"The effect of resistance exercise on sleep: a systematic review of randomized controlled trials. Sleep Med","volume":"39","author":"Kovacevic","year":"2018","journal-title":"Rev"},{"key":"B100","doi-asserted-by":"publisher","first-page":"556","DOI":"10.1186\/s12888-024-05943-5","article-title":"Comorbidity of binge eating disorder and other psychiatric disorders: a systematic review","volume":"24","author":"Kowalewska","year":"2024","journal-title":"BMC Psychiatry"},{"key":"B101","doi-asserted-by":"publisher","first-page":"1270","DOI":"10.1249\/MSS.0000000000001939","article-title":"Physical activity, all-cause and cardiovascular mortality, and cardiovascular disease","volume":"51","author":"Kraus","year":"2019","journal-title":"Med. Sci. Sports Exerc"},{"key":"B102","doi-asserted-by":"publisher","first-page":"2227","DOI":"10.1016\/j.numecd.2024.06.008","article-title":"Sex differences in the association between short sleep duration and obesity: a systematic review and meta-analysis. Nutr. Metab. Cardiovasc","volume":"34","author":"Lange","year":"2024","journal-title":"Dis"},{"key":"B103","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1053\/smrv.2002.0261","article-title":"Obstructive sleep apnoea syndrome\u2014an oxidative stress disorder. Sleep Med","volume":"7","author":"Lavie","year":"2003","journal-title":"Rev"},{"key":"B104","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1016\/j.smrv.2014.07.003","article-title":"Oxidative stress in obstructive sleep apnea and intermittent hypoxia revisited\u2014the bad ugly and good: implications to the heart and brain","volume":"20","author":"Lavie","year":"2015","journal-title":"Sleep Med. Rev"},{"key":"B105","doi-asserted-by":"publisher","first-page":"1339","DOI":"10.1016\/j.cell.2014.05.012","article-title":"Increased adipocyte O2 consumption triggers HIF-1\u03b1, causing inflammation and insulin resistance in obesity","volume":"157","author":"Lee","year":"2014","journal-title":"Cell"},{"key":"B106","doi-asserted-by":"publisher","first-page":"3297","DOI":"10.1038\/s41467-025-58271-x","article-title":"Dose-response relationship between evening exercise and sleep","volume":"16","author":"Leota","year":"2025","journal-title":"Nat. Commun"},{"key":"B107","doi-asserted-by":"publisher","first-page":"15015","DOI":"10.1038\/nrdp.2015.15","article-title":"Obstructive sleep apnoea syndrome. Nat. Rev. Dis","volume":"1","author":"L\u00e9vy","year":"2015","journal-title":"Primers"},{"key":"B108","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1038\/s41574-020-0318-z","article-title":"Food as a circadian time cue - evidence from human studies","volume":"16","author":"Lewis","year":"2020","journal-title":"Nat. Rev. Endocrinol"},{"key":"B109","doi-asserted-by":"publisher","first-page":"e354","DOI":"10.1097\/jnr.0000000000000628","article-title":"Association between social jetlag and components of metabolic syndrome: a systematic review and meta-analysis","volume":"32","author":"Lin","year":"2024","journal-title":"J. Nurs. Res"},{"key":"B110","doi-asserted-by":"publisher","first-page":"742","DOI":"10.1097\/HJH.0000000000003654","article-title":"Effect of 12-week high-intensity interval training on hemodynamic variables at rest and during exercise in patients with obstructive sleep apnoea","volume":"42","author":"Lins-Filho","year":"2024","journal-title":"J. Hypertens"},{"key":"B111","doi-asserted-by":"publisher","first-page":"106428","DOI":"10.1016\/j.appet.2022.106428","article-title":"Effects of acute resistance exercise with different loads on appetite, appetite hormones and autonomic nervous system responses in healthy young men","volume":"182","author":"Liu","year":"2023","journal-title":"Appetite"},{"key":"B112","doi-asserted-by":"publisher","first-page":"e2442163","DOI":"10.1001\/jamanetworkopen.2024.42163","article-title":"Meal timing and anthropometric and metabolic outcomes: a systematic review and meta-analysis","volume":"7","author":"Liu","year":"2024","journal-title":"JAMA Netw Open"},{"key":"B113","doi-asserted-by":"publisher","first-page":"1677087","DOI":"10.3389\/fspor.2025.1677087","article-title":"Effect of exercise on abdominal obesity and inflammatory response in the older adults: a systematic review and meta-analysis of randomized controlled trials","volume":"7","author":"Liu","year":"2026","journal-title":"Front. Sports Act Living"},{"key":"B114","doi-asserted-by":"publisher","first-page":"e13428","DOI":"10.1111\/obr.13428","article-title":"Resistance training effectiveness on body composition and body weight outcomes in individuals with overweight and obesity across the lifespan: a systematic review and meta-analysis. Obes","volume":"23","author":"Lopez","year":"2022","journal-title":"Rev"},{"key":"B115","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1007\/s00394-025-03600-5","article-title":"Association between shift work and eating behaviours, sleep quality, and mental health among Italian workers","volume":"64","author":"Lotti","year":"2025","journal-title":"Eur. J. Nutr"},{"key":"B116","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1001\/archgenpsychiatry.2010.2","article-title":"Overweight, obesity, and depression: a systematic review and meta-analysis of longitudinal studies. Arch. Gen","volume":"67","author":"Luppino","year":"2010","journal-title":"Psychiatry"},{"key":"B117","doi-asserted-by":"publisher","first-page":"1582","DOI":"10.1002\/oby.21126","article-title":"Diet and exercise improve chemoreflex sensitivity in patients with metabolic syndrome and obstructive sleep apnea","volume":"23","author":"Maki-Nunes","year":"2015","journal-title":"Obesity"},{"key":"B118","doi-asserted-by":"publisher","first-page":"e15790","DOI":"10.1016\/j.heliyon.2023.e15790","article-title":"Improvement of adiponectin in relation to physical performance and body composition in young obese males subjected to twenty-four weeks of training programs","volume":"9","author":"Mallardo","year":"2023","journal-title":"Heliyon"},{"key":"B119","doi-asserted-by":"publisher","first-page":"1113","DOI":"10.1007\/s40279-014-0197-3","article-title":"High responders and low responders: factors associated with individual variation in response to standardized training","volume":"44","author":"Mann","year":"2014","journal-title":"Sports Med"},{"key":"B120","doi-asserted-by":"publisher","first-page":"272","DOI":"10.1038\/s41574-023-00805-8","article-title":"Metabolism and exercise: the skeletal muscle clock takes centre stage","volume":"19","author":"Martin","year":"2023","journal-title":"Nat. Rev. Endocrinol"},{"key":"B121","doi-asserted-by":"publisher","first-page":"979","DOI":"10.1017\/S0007114520001804","article-title":"Social jetlag, eating behaviours and BMI among adolescents in the USA","volume":"124","author":"Mathew","year":"2020","journal-title":"Br J Nutr"},{"key":"B122","doi-asserted-by":"publisher","first-page":"1597","DOI":"10.3390\/ijms20071597","article-title":"Off the clock: from circadian disruption to metabolic disease","volume":"20","author":"Maury","year":"2019","journal-title":"Int. J. Mol. Sci"},{"key":"B123","doi-asserted-by":"publisher","first-page":"222","DOI":"10.1016\/j.pharmthera.2007.02.003","article-title":"Circadian genes, rhythms and the biology of mood disorders","volume":"114","author":"McClung","year":"2007","journal-title":"Pharmacol Ther"},{"key":"B124","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1111\/obr.12503","article-title":"Role of sleep and circadian disruption on energy expenditure and in metabolic predisposition to human obesity and metabolic disease","volume":"18","author":"McHill","year":"2017","journal-title":"Obes. Rev"},{"key":"B125","doi-asserted-by":"publisher","first-page":"73","DOI":"10.3389\/fneur.2018.00073","article-title":"Obstructive sleep apnea syndrome, objectively measured physical activity and exercise training interventions: a systematic review and meta-analysis. Front","volume":"9","author":"Mendelson","year":"2018","journal-title":"Neurol"},{"key":"B126","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1111\/ijpo.12015","article-title":"Sleep quality, sleep duration and physical activity in obese adolescents: effects of exercise training. Pediatr","volume":"11","author":"Mendelson","year":"2016","journal-title":"Obes"},{"key":"B127","doi-asserted-by":"publisher","first-page":"e2214756121","DOI":"10.1073\/pnas.2214756121","article-title":"The sleep-circadian interface: a window into mental disorders","volume":"121","author":"Meyer","year":"2024","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"B128","doi-asserted-by":"publisher","first-page":"395","DOI":"10.1177\/1559827613488867","article-title":"Long-term adherence to health behavior change","volume":"7","author":"Middleton","year":"2013","journal-title":"Am. J. Lifestyle Med"},{"key":"B129","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1038\/s41380-018-0017-5","article-title":"Depression and obesity: evidence of shared biological mechanisms. Mol","volume":"24","author":"Milaneschi","year":"2019","journal-title":"Psychiatry"},{"key":"B130","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1016\/j.smhs.2023.12.003","article-title":"Responsiveness of functional performance and muscle strength, power, and size to resistance training: a systematic review","volume":"6","author":"Moda","year":"2024","journal-title":"Sports Med. Health Sci"},{"key":"B131","doi-asserted-by":"publisher","first-page":"755","DOI":"10.1136\/bjsports-2021-105061","article-title":"Muscle-strengthening activities are associated with lower risk and mortality in major non-communicable diseases: a systematic review and meta-analysis of cohort studies","volume":"56","author":"Momma","year":"2022","journal-title":"Br. J. Sports Med"},{"key":"B132","doi-asserted-by":"publisher","first-page":"1701972","DOI":"10.1183\/13993003.01972-2017","article-title":"Physical activity as a moderator for OSA and cardiometabolic risk in EPISONO study. Eur. Respir","volume":"51","author":"M\u00f4nico-Neto","year":"2018","journal-title":"J"},{"key":"B133","doi-asserted-by":"publisher","first-page":"11590","DOI":"10.3390\/ijms262311590","article-title":"Obesity and depression: a pathophysiotoxic relationship","volume":"26","author":"Monsalve","year":"2025","journal-title":"Int. J. Mol. Sci"},{"key":"B134","doi-asserted-by":"publisher","first-page":"E2225","DOI":"10.1073\/pnas.1418955112","article-title":"Endogenous circadian system and circadian misalignment impact glucose tolerance via separate mechanisms in humans","volume":"112","author":"Morris","year":"2015","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"B135","doi-asserted-by":"publisher","DOI":"10.1111\/obr.70139","article-title":"The effect of behavioral sleep interventions on measures of obesity, dietary intake and physical activity in adults with poor sleep health: a systematic review, meta-analysis and meta-regression analysis","author":"Mostafa","year":"2026","journal-title":"Obes Rev."},{"key":"B136","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1016\/j.resp.2008.07.006","article-title":"Transcriptional responses to intermittent hypoxia","volume":"164","author":"Nanduri","year":"2008","journal-title":"Respir. Physiol. Neurobiol"},{"key":"B137","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1111\/nuf.12659","article-title":"Sleep quality: an evolutionary concept analysis. Nurs","volume":"57","author":"Nelson","year":"2022","journal-title":"Forum"},{"key":"B138","doi-asserted-by":"publisher","first-page":"702","DOI":"10.1016\/j.cmet.2023.12.025","article-title":"Understanding the variation in exercise responses to guide personalized physical activity prescriptions","volume":"36","author":"Noone","year":"2024","journal-title":"Cell Metab"},{"key":"B139","doi-asserted-by":"publisher","first-page":"e009773","DOI":"10.1136\/bmjgh-2022-009773","article-title":"Economic impacts of overweight and obesity: current and future estimates for 161 countries","volume":"7","author":"Okunogbe","year":"2022","journal-title":"BMJ Glob. Health"},{"key":"B140","doi-asserted-by":"publisher","first-page":"821199","DOI":"10.3389\/fphys.2022.821199","article-title":"Wheel-running facilitates phase advances in locomotor and peripheral circadian rhythm in social jet lag model mice","volume":"13","author":"Oneda","year":"2022","journal-title":"Front. Physiol"},{"key":"B141","doi-asserted-by":"publisher","DOI":"10.1111\/obr.13273","article-title":"Exercise training in the management of overweight and obesity in adults: synthesis of the evidence and recommendations from the European Association for the Study of Obesity Physical Activity Working Group","volume":"22","author":"Oppert","year":"2021","journal-title":"Obes. Rev"},{"key":"B142","doi-asserted-by":"publisher","first-page":"631","DOI":"10.3390\/healthcare14050631","article-title":"Physical activity as a habit in long-term care: a multidisciplinary guideline","volume":"14","author":"Oppewal","year":"2026","journal-title":"Healthcare"},{"key":"B143","doi-asserted-by":"publisher","first-page":"214","DOI":"10.1016\/j.jphys.2020.09.009","article-title":"Resistance training leads to large improvements in strength and moderate improvements in physical function in adults who are overweight or obese: a systematic review","volume":"66","author":"Orange","year":"2020","journal-title":"J. Physiother"},{"key":"B144","doi-asserted-by":"publisher","first-page":"1008","DOI":"10.1126\/science.aah4967","article-title":"Circadian physiology of metabolism","volume":"354","author":"Panda","year":"2016","journal-title":"Science"},{"key":"B145","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1016\/j.ecl.2024.10.010","article-title":"Exploring the bidirectional relationship between depression and obesity","volume":"54","author":"Park","year":"2025","journal-title":"Endocrinol. Metab. Clin. North Am"},{"key":"B146","doi-asserted-by":"publisher","first-page":"842","DOI":"10.1038\/ijo.2014.201","article-title":"Social jetlag, obesity and metabolic disorder: investigation in a cohort study","volume":"39","author":"Parsons","year":"2015","journal-title":"Int. J. Obes."},{"key":"B147","doi-asserted-by":"publisher","first-page":"1121","DOI":"10.3758\/s13415-018-0626-0","article-title":"The brain-adipocyte-gut network: linking obesity and depression subtypes","volume":"18","author":"Patist","year":"2018","journal-title":"Cogn. Affect. Behav. Neurosci"},{"key":"B148","doi-asserted-by":"publisher","first-page":"550","DOI":"10.1001\/jamapsychiatry.2022.0609","article-title":"Association between physical activity and risk of depression: a systematic review and meta-analysis","volume":"79","author":"Pearce","year":"2022","journal-title":"JAMA Psychiatry"},{"key":"B149","doi-asserted-by":"publisher","first-page":"4903","DOI":"10.1523\/JNEUROSCI.4768-08.2009","article-title":"NADPH oxidase is required for the sensory plasticity of the carotid body by chronic intermittent hypoxia","volume":"29","author":"Peng","year":"2009","journal-title":"J. Neurosci"},{"key":"B150","doi-asserted-by":"publisher","first-page":"10073","DOI":"10.1073\/pnas.1734109100","article-title":"Induction of sensory long-term facilitation in the carotid body by intermittent hypoxia: implications for recurrent apneas","volume":"100","author":"Peng","year":"2003","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"B151","doi-asserted-by":"publisher","first-page":"1313545","DOI":"10.3389\/fphys.2024.1313545","article-title":"Effects of acute bouts of evening resistance or endurance exercises on sleep EEG and salivary cortisol. Front","volume":"15","author":"Perrier","year":"2024","journal-title":"Physiol"},{"key":"B152","doi-asserted-by":"publisher","first-page":"1359772","DOI":"10.3389\/fendo.2024.1359772","article-title":"Meal timing and its role in obesity and associated diseases","volume":"15","author":"Peters","year":"2024","journal-title":"Front. Endocrinol"},{"key":"B153","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s40279-018-01041-1","article-title":"Do non-responders to exercise exist\u2014and if so, what should we do about them?","volume":"49","author":"Pickering","year":"2019","journal-title":"Sports Med"},{"key":"B154","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1016\/j.metabol.2017.11.017","article-title":"Circadian regulation of glucose, lipid, and energy metabolism in humans","volume":"84","author":"Poggiogalle","year":"2018","journal-title":"Metabolism"},{"key":"B155","doi-asserted-by":"publisher","first-page":"4981","DOI":"10.3390\/ijerph19094981","article-title":"The benefits of physical activity for people with obesity, independent of weight loss: a systematic review","volume":"19","author":"Pojednic","year":"2022","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"B156","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1183\/09031936.00019913","article-title":"Visceral white fat remodelling contributes to intermittent hypoxia-induced atherogenesis","volume":"43","author":"Poulain","year":"2014","journal-title":"Eur. Respir. J"},{"key":"B157","doi-asserted-by":"publisher","first-page":"282","DOI":"10.1016\/j.tem.2016.03.005","article-title":"Circadian system and glucose metabolism: implications for physiology and disease. Trends Endocrinol","volume":"27","author":"Qian","year":"2016","journal-title":"Metab"},{"key":"B158","doi-asserted-by":"publisher","first-page":"240128","DOI":"10.1155\/2013\/240128","article-title":"The clinical obesity maintenance model: an integration of psychological constructs including mood, emotional regulation, disordered overeating, habitual cluster behaviours, health literacy and cognitive function","volume":"2013","author":"Raman","year":"2013","journal-title":"J. Obes"},{"key":"B159","doi-asserted-by":"publisher","first-page":"6191","DOI":"10.3390\/app15116191","article-title":"Exercise suppresses appetite in obesity: a biochemical, metabolic, and molecular approach","volume":"15","author":"Razi","year":"2025","journal-title":"Appl. Sci"},{"key":"B160","doi-asserted-by":"publisher","first-page":"856","DOI":"10.1164\/rccm.201412-2192LE","article-title":"Attenuation of obstructive sleep apnea and overnight rostral fluid shift by physical activity","volume":"191","author":"Redolfi","year":"2015","journal-title":"Am. J. Respir. Crit. Care Med"},{"key":"B161","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1164\/rccm.200807-1076OC","article-title":"Relationship between overnight rostral fluid shift and obstructive sleep apnea in nonobese men","volume":"179","author":"Redolfi","year":"2009","journal-title":"Am. J. Respir. Crit. Care Med"},{"key":"B162","doi-asserted-by":"publisher","first-page":"935","DOI":"10.1038\/nature00965","article-title":"Coordination of circadian timing in mammals","volume":"418","author":"Reppert","year":"2002","journal-title":"Nature"},{"key":"B163","doi-asserted-by":"publisher","first-page":"2135","DOI":"10.3390\/nu17132135","article-title":"Chrononutrition and energy balance: how meal timing and circadian rhythms shape weight regulation and metabolic health","volume":"17","author":"Reytor-Gonz\u00e1lez","year":"2025","journal-title":"Nutrients"},{"key":"B164","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1016\/j.ejim.2021.04.017","article-title":"Obesity and sleep disturbances: the \u201cchicken or the egg\u201d question. Eur. J. Intern","volume":"92","author":"Rodrigues","year":"2021","journal-title":"Med"},{"key":"B165","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1016\/j.cub.2012.03.038","article-title":"Social jetlag and obesity","volume":"22","author":"Roenneberg","year":"2012","journal-title":"Curr. Biol"},{"key":"B166","doi-asserted-by":"publisher","first-page":"978412","DOI":"10.3389\/fnut.2022.978412","article-title":"A matter of time: a systematic scoping review on a potential role of the circadian system in binge eating behavior","volume":"9","author":"Romo-Nava","year":"2022","journal-title":"Front. Nutr"},{"key":"B167","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1007\/s11154-023-09853-x","article-title":"Circadian alignment of food intake and glycaemic control by time-restricted eating: a systematic review and meta-analysis","volume":"25","author":"Rovira-Llopis","year":"2024","journal-title":"Rev. Endocr. Metab. Disord"},{"key":"B168","doi-asserted-by":"publisher","first-page":"2423","DOI":"10.1113\/JP273312","article-title":"Adipose tissue inflammation by intermittent hypoxia: mechanistic link between obstructive sleep apnoea and metabolic dysfunction","volume":"595","author":"Ryan","year":"2017","journal-title":"J. Physiol"},{"key":"B169","doi-asserted-by":"publisher","first-page":"S4201","DOI":"10.21037\/jtd.2018.08.56","article-title":"Mechanisms of cardiovascular disease in obstructive sleep apnoea","volume":"10","author":"Ryan","year":"2018","journal-title":"J. Thorac. Dis"},{"key":"B170","doi-asserted-by":"publisher","first-page":"6367","DOI":"10.1113\/JP287024","article-title":"Running the clock: new insights into exercise and circadian rhythms for optimal metabolic health","volume":"602","author":"Rynders","year":"2024","journal-title":"J. Physiol"},{"key":"B171","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1186\/s12966-017-0494-y","article-title":"Effective behaviour change techniques for physical activity and healthy eating in overweight and obese adults; systematic review and meta-regression analyses","volume":"14","author":"Samdal","year":"2017","journal-title":"Int. J. Behav. Nutr. Phys. Act"},{"key":"B172","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1159\/000437173","article-title":"Role of exercise in the activation of brown adipose tissue","volume":"67","author":"Sanchez-Delgado","year":"2015","journal-title":"Ann. Nutr. Metab"},{"key":"B173","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1007\/s00125-018-4767-z","article-title":"Afternoon exercise is more efficacious than morning exercise at improving blood glucose levels in individuals with type 2 diabetes: a randomised crossover trial","volume":"62","author":"Savikj","year":"2019","journal-title":"Diabetologia"},{"key":"B174","doi-asserted-by":"publisher","first-page":"316","DOI":"10.1016\/j.pharmthera.2012.06.004","article-title":"Ghrelin signalling and obesity: at the interface of stress, mood and food reward. Pharmacol","volume":"135","author":"Schellekens","year":"2012","journal-title":"Ther"},{"key":"B175","doi-asserted-by":"publisher","first-page":"1872454","DOI":"10.3389\/fnut.2026.1872454","article-title":"Time-restricted eating and metabolic health: implications for nutritional strategies and weight loss. Front","volume":"13","author":"Schimenes","year":"2026","journal-title":"Nutr"},{"key":"B176","doi-asserted-by":"publisher","first-page":"167561","DOI":"10.1016\/j.bbadis.2024.167561","article-title":"Depression and obesity: focus on factors and mechanistic links. Biochim. Biophys. Acta Mol","volume":"1871","author":"Selman","year":"2025","journal-title":"Basis Dis"},{"key":"B177","doi-asserted-by":"publisher","first-page":"9646","DOI":"10.3390\/ijerph19159646","article-title":"Association between chronotype, physical activity and sedentary behaviour: a systematic review","volume":"19","author":"Sempere-Rubio","year":"2022","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"B178","doi-asserted-by":"publisher","first-page":"1282357","DOI":"10.3389\/fphar.2023.1282357","article-title":"Effects of exercise on circadian rhythms in humans. Front","volume":"14","author":"Shen","year":"2023","journal-title":"Pharmacol"},{"key":"B179","doi-asserted-by":"publisher","first-page":"18298","DOI":"10.1038\/s41598-025-02659-8","article-title":"Differential benefits of 12-week morning vs. evening aerobic exercise on sleep and cardiometabolic health: a randomized controlled trial. Sci","volume":"15","author":"Shen","year":"2025","journal-title":"Rep"},{"key":"B180","doi-asserted-by":"publisher","first-page":"2187","DOI":"10.3760\/cma.j.issn.0376-2491.2019.28.007","article-title":"Efficacy of nasal CPAP and aerobic exercise of different intensity in patients with obstructive sleep apnea hypopnea syndrome and type 2 diabetes mellitus","volume":"99","author":"Shen","year":"2019","journal-title":"Zhonghua Yi Xue Za Zhi"},{"key":"B181","doi-asserted-by":"publisher","first-page":"e12966","DOI":"10.1111\/obr.12966","article-title":"Depression subtypes and obesity in adults: a systematic review and meta-analysis. Obes","volume":"21","author":"Silva","year":"2020","journal-title":"Rev"},{"key":"B182","doi-asserted-by":"publisher","first-page":"e20180085","DOI":"10.1590\/1806-3713\/e20180085","article-title":"Effects of exercise on sleep symptoms in patients with severe obstructive sleep apnea","volume":"45","author":"Silva","year":"2019","journal-title":"J. Bras. Pneumol"},{"key":"B183","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1038\/s41574-018-0122-1","article-title":"Circadian clocks and insulin resistance. Nat. Rev","volume":"15","author":"Stenvers","year":"2019","journal-title":"Endocrinol"},{"key":"B184","doi-asserted-by":"publisher","first-page":"102058","DOI":"10.1016\/j.gde.2023.102058","article-title":"Exercise-induced regulation of adipose tissue","volume":"81","author":"Stroh","year":"2023","journal-title":"Curr. Opin. Genet. Dev"},{"key":"B185","doi-asserted-by":"publisher","first-page":"330","DOI":"10.1016\/S0006-3223(03)00608-5","article-title":"Depression and obesity","volume":"54","author":"Stunkard","year":"2003","journal-title":"Biol. Psychiatry"},{"key":"B186","doi-asserted-by":"publisher","first-page":"289","DOI":"10.3389\/fpubh.2016.00289","article-title":"Behavior change with fitness technology in sedentary adults: a review of the evidence for increasing physical activity","volume":"4","author":"Sullivan","year":"2017","journal-title":"Front. Public Health"},{"key":"B187","doi-asserted-by":"publisher","first-page":"270","DOI":"10.1016\/j.jad.2023.01.094","article-title":"Diet and depression: a systematic review of whole dietary interventions as treatment in patients with depression. J. Affect","volume":"327","author":"Swainson","year":"2023","journal-title":"Disord"},{"key":"B188","doi-asserted-by":"publisher","first-page":"121417","DOI":"10.1016\/j.jad.2026.121417","article-title":"Irregular meal frequency and depressive symptoms: moderating roles of dietary diversity and breakfast skipping","volume":"404","author":"Tae","year":"2026","journal-title":"J. Affect. Disord"},{"key":"B189","doi-asserted-by":"publisher","first-page":"e62","DOI":"10.1371\/journal.pmed.0010062","article-title":"Short sleep duration is associated with reduced leptin, elevated ghrelin, and increased body mass index","volume":"1","author":"Taheri","year":"2004","journal-title":"PLoS Med"},{"key":"B190","doi-asserted-by":"publisher","first-page":"764","DOI":"10.1038\/nrg2430","article-title":"The genetics of mammalian circadian order and disorder: implications for physiology and disease","volume":"9","author":"Takahashi","year":"2008","journal-title":"Nat. Rev. Genet"},{"key":"B191","doi-asserted-by":"publisher","first-page":"1548282","DOI":"10.3389\/fpsyt.2025.1548282","article-title":"Association of skipping breakfast with depression: a systematic review and meta-analysis","volume":"16","author":"Tan","year":"2025","journal-title":"Front. Psychiatry"},{"key":"B192","doi-asserted-by":"publisher","first-page":"137","DOI":"10.4082\/kjfm.24.0312","article-title":"Interactions between exercise, environmental factors, and diet in modulating appetite-regulating hormones: implications for athletes and physically active individuals","volume":"46","author":"Tanwar","year":"2025","journal-title":"Korean J. Fam. Med"},{"key":"B193","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1249\/MSS.0000000000002139","article-title":"Exercise timing in type 2 diabetes mellitus: a systematic review","volume":"52","author":"Teo","year":"2020","journal-title":"Med. Sci. Sports Exerc"},{"key":"B194","doi-asserted-by":"publisher","first-page":"6795","DOI":"10.1073\/pnas.0936797100","article-title":"Adrenergic regulation of clock gene expression in mouse liver","volume":"100","author":"Terazono","year":"2003","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"B195","doi-asserted-by":"publisher","first-page":"9990","DOI":"10.3390\/ijerph18199990","article-title":"Subjective and objective consequences of stress in subjects with subjectively different sleep quality\u2014a cross-sectional study","volume":"18","author":"Thielmann","year":"2021","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"B196","doi-asserted-by":"publisher","first-page":"1487","DOI":"10.1152\/japplphysiol.01295.2009","article-title":"Using molecular classification to predict gains in maximal aerobic capacity following endurance exercise training in humans","volume":"108","author":"Timmons","year":"2010","journal-title":"J. Appl. Physiol"},{"key":"B197","doi-asserted-by":"publisher","first-page":"e13","DOI":"10.2105\/AJPH.2019.305278","article-title":"Shift work and poor mental health: a meta-analysis of longitudinal studies","volume":"109","author":"Torquati","year":"2019","journal-title":"Am J Public Health"},{"key":"B198","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1017\/S0007114508971282","article-title":"Hypoxia in adipose tissue: a basis for the dysregulation of tissue function in obesity?","volume":"100","author":"Trayhurn","year":"2008","journal-title":"Br. J. Nutr"},{"key":"B199","doi-asserted-by":"publisher","first-page":"320","DOI":"10.1164\/rccm.200805-669OC","article-title":"Lifestyle intervention with weight reduction: first-line treatment in mild obstructive sleep apnea","volume":"179","author":"Tuomilehto","year":"2009","journal-title":"Am. J. Respir. Crit. Care Med"},{"key":"B200","doi-asserted-by":"publisher","first-page":"e13239","DOI":"10.1111\/obr.13239","article-title":"Effect of different types of regular exercise on physical fitness in adults with overweight or obesity: systematic review and meta-analyses","volume":"22","author":"van Baak","year":"2021","journal-title":"Obes. Rev"},{"key":"B201","doi-asserted-by":"publisher","first-page":"566","DOI":"10.1007\/s10865-022-00377-4","article-title":"Mental health and quality of life during weight loss in females with clinically severe obesity: a randomized clinical trial","volume":"46","author":"van den Hoek","year":"2023","journal-title":"J. Behav. Med"},{"key":"B202","doi-asserted-by":"publisher","first-page":"4289","DOI":"10.1113\/jphysiol.2010.196493","article-title":"Training in the fasted state improves glucose tolerance during fat-rich diet","volume":"588","author":"Van Proeyen","year":"2010","journal-title":"J. Physiol."},{"key":"B203","doi-asserted-by":"publisher","first-page":"405","DOI":"10.3109\/07420528.2014.986273","article-title":"Chronotype influences activity circadian rhythm and sleep: differences in sleep quality between weekdays and weekend","volume":"32","author":"Vitale","year":"2015","journal-title":"Chronobiol. Int"},{"key":"B204","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1016\/j.tics.2010.11.001","article-title":"Reward, dopamine and the control of food intake: implications for obesity","volume":"15","author":"Volkow","year":"2011","journal-title":"Trends Cogn. Sci"},{"key":"B205","doi-asserted-by":"publisher","first-page":"464","DOI":"10.1177\/10998004241313332","article-title":"The impact of exercise training on psychological outcomes, body composition, and quality of life in overweight or obese adults: a systematic review and meta-analysis of randomized controlled trials","volume":"27","author":"Vosadi","year":"2025","journal-title":"Biol. Res. Nurs"},{"key":"B206","doi-asserted-by":"publisher","first-page":"1766438","DOI":"10.3389\/fpubh.2026.1766438","article-title":"Network meta-analysis and dose-response analysis of exercise on sleep quality and BMI in obese populations. Front","volume":"14","author":"Wang","year":"2026","journal-title":"Public Health"},{"key":"B207","doi-asserted-by":"publisher","first-page":"106680","DOI":"10.1016\/j.sleep.2025.106680","article-title":"Comparative efficacy of exercise modalities on sleep architecture in adults with sleep disorders: a systematic review and network meta-analysis of randomized controlled trials","volume":"134","author":"Wang","year":"2025","journal-title":"Sleep Med"},{"key":"B208","doi-asserted-by":"publisher","first-page":"921085","DOI":"10.3389\/fimmu.2022.921085","article-title":"Effect of exercise training on body composition and inflammatory cytokine levels in overweight and obese individuals: a systematic review and network meta-analysis. Front","volume":"13","author":"Wang","year":"2022","journal-title":"Immunol"},{"key":"B209","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1016\/j.jshs.2013.11.004","article-title":"Sleep quality improved following a single session of moderate-intensity aerobic exercise in older women: results from a pilot study","volume":"3","author":"Wang","year":"2014","journal-title":"J. Sport Health Sci"},{"key":"B210","doi-asserted-by":"publisher","first-page":"1179","DOI":"10.1113\/jphysiol.2012.245159","article-title":"Role of nocturnal rostral fluid shift in the pathogenesis of obstructive and central sleep apnoea","volume":"591","author":"White","year":"2013","journal-title":"J. Physiol"},{"key":"B211","doi-asserted-by":"publisher","first-page":"1831","DOI":"10.1152\/japplphysiol.01370.2011","article-title":"Effects of aerobic and\/or resistance training on body mass and fat mass in overweight or obese adults","volume":"113","author":"Willis","year":"2012","journal-title":"J. Appl. Physiol."},{"key":"B212","doi-asserted-by":"publisher","first-page":"497","DOI":"10.1080\/07420520500545979","article-title":"Social jetlag: misalignment of biological and social time","volume":"23","author":"Wittmann","year":"2006","journal-title":"Chronobiol. Int."},{"key":"B213","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1016\/j.cophys.2019.04.020","article-title":"Exercise timing and circadian rhythms","volume":"10","author":"Wolff","year":"2019","journal-title":"Curr. Opin. Physiol"},{"key":"B214","unstructured":"Physical Activity\n          \n          2024"},{"key":"B215","unstructured":"Obesity and Overweight\n          \n          2025"},{"key":"B216","unstructured":"The Economic Impact of Overweight and Obesity 2nd Edition with Estimates for 161 Countries\n          \n          2022"},{"key":"B217","unstructured":"World Obesity Atlas 2025\n          \n          2025"},{"key":"B218","doi-asserted-by":"publisher","first-page":"107955","DOI":"10.1016\/j.ypmed.2024.107955","article-title":"The optimal exercise intervention for sleep quality in adults: a systematic review and network meta-analysis","volume":"183","author":"Xie","year":"2024","journal-title":"Prev. Med"},{"key":"B219","doi-asserted-by":"publisher","first-page":"1518143","DOI":"10.3389\/fnut.2025.1518143","article-title":"Effect of long-term exercise on circulating ghrelin in overweight and obese individuals: a systematic review and meta-analysis","volume":"12","author":"Xin","year":"2025","journal-title":"Front. Nutr"},{"key":"B220","doi-asserted-by":"publisher","first-page":"101877","DOI":"10.1016\/j.smrv.2023.101877","article-title":"Comparative efficacy of exercise modalities on sleep quality in populations with sleep disorders: a systematic review and network meta-analysis. Sleep Med","volume":"73","author":"Xu","year":"2024","journal-title":"Rev"},{"key":"B221","doi-asserted-by":"publisher","first-page":"e2328798","DOI":"10.1001\/jamanetworkopen.2023.28798","article-title":"Lifestyle factors in the association of shift work and depression and anxiety","volume":"6","author":"Xu","year":"2023","journal-title":"JAMA Netw. Open"},{"key":"B222","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1016\/S1836-9553(12)70106-6","article-title":"Exercise training improves sleep quality in middle-aged and older adults with sleep problems: a systematic review","volume":"58","author":"Yang","year":"2012","journal-title":"J. Physiother"},{"key":"B223","doi-asserted-by":"publisher","first-page":"2253","DOI":"10.1113\/JP276943","article-title":"Human circadian phase-response curves for exercise","volume":"597","author":"Youngstedt","year":"2019","journal-title":"J. Physiol"},{"key":"B224","doi-asserted-by":"publisher","first-page":"103","DOI":"10.5493\/wjem.v5.i2.103","article-title":"Mood disorders: a potential link between ghrelin and leptin on human body?","volume":"5","author":"Zarouna","year":"2015","journal-title":"World J. Exp. Med"},{"key":"B225","doi-asserted-by":"publisher","first-page":"1008820","DOI":"10.3389\/fendo.2022.1008820","article-title":"The association between metabolic parameters and evening chronotype and social jetlag in non-shift workers: a meta-analysis. Front","volume":"13","author":"Zhang","year":"2022","journal-title":"Endocrinol"},{"key":"B226","doi-asserted-by":"publisher","first-page":"1556784","DOI":"10.3389\/fneur.2025.1556784","article-title":"Effects of sleep deprivation on heart rate variability: a systematic review and meta-analysis. Front","volume":"16","author":"Zhang","year":"2025","journal-title":"Neurol"},{"key":"B227","doi-asserted-by":"publisher","first-page":"589","DOI":"10.3390\/metabo14110589","article-title":"Exercise as a therapeutic strategy for obesity: central and peripheral mechanisms","volume":"14","author":"Zhang","year":"2024","journal-title":"Metabolites"},{"key":"B228","doi-asserted-by":"publisher","first-page":"378","DOI":"10.3389\/fnins.2019.00378","article-title":"Role of leptin in mood disorder and neurodegenerative disease. Front","volume":"13","author":"Zou","year":"2019","journal-title":"Neurosci"}],"container-title":["Frontiers in Sleep"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/frsle.2026.1943600\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T13:27:12Z","timestamp":1789133232000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/frsle.2026.1943600\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,11]]},"references-count":228,"alternative-id":["10.3389\/frsle.2026.1943600"],"URL":"https:\/\/doi.org\/10.3389\/frsle.2026.1943600","relation":{},"ISSN":["2813-2890"],"issn-type":[{"value":"2813-2890","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,11]]},"article-number":"1943600"}}