{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T07:46:07Z","timestamp":1787989567999,"version":"build-2784847793"},"reference-count":80,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,7,3]],"date-time":"2023-07-03T00:00:00Z","timestamp":1688342400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Transplant."],"abstract":"<jats:p>The first successful human liver transplant (LT) was done over 60 years ago; since the early pioneering days, this procedure has become a routine treatment with excellent outcomes for the great majority of recipients. Over the last six decades, indications have evolved. Use of LT for hepatic malignancy is becoming less common as factors that define a successful outcome are being increasingly defined, and alternative therapeutic options become available. Both Hepatitis B and C virus associated liver disease are becoming less common indications as medical treatments become more effective in preventing end-stage disease. Currently, the most common indications are alcohol-related liver disease and metabolic associated liver disease. The developing (and controversial) indications include acute on chronic liver failure, alcoholic hepatitis and some rarer malignancies such as non-resectable colorectal cancer liver metastases, neuroendocrine tumours and cholangiocarcinoma. Candidates are becoming older and with greater comorbidities, A relative shortage of donor organs remains the greatest cause for reducing access to LT; therefore, various countries have developed transparent approaches to allocation of this life saving and life enhancing resource. Reliance on prognostic models has gone some way to improve transparency and increase equity of access but these approaches have their limitations.<\/jats:p>","DOI":"10.3389\/frtra.2023.1178452","type":"journal-article","created":{"date-parts":[[2023,7,3]],"date-time":"2023-07-03T07:30:51Z","timestamp":1688369451000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":4,"title":["The evolution of the liver transplant candidate"],"prefix":"10.3389","volume":"2","author":[{"given":"Angus","family":"Hann","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Neuberger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2023,7,3]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"1869","DOI":"10.1002\/hep.23595","article-title":"Themes of liver transplantation","volume":"51","author":"Starzl","year":"2010","journal-title":"Hepatology"},{"key":"B2","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1111\/j.1749-6632.1970.tb37018.x","article-title":"Liver transplantation in man","volume":"170","author":"Penn","year":"1970","journal-title":"Ann N Y Acad Sci"},{"key":"B3","first-page":"659","article-title":"Homotransplantation of the liver in humans","volume":"117","author":"Starzl","year":"1963","journal-title":"Surg Gynecol Obstet"},{"key":"B4","doi-asserted-by":"crossref","first-page":"107S","DOI":"10.1002\/hep.1840040725","article-title":"National institutes of health consensus development conference statement: liver transplantation\u2013June 20-23, 1983","volume":"4","year":"1984","journal-title":"Hepatology"},{"key":"B5","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1126\/science.6344219","article-title":"Liver transplants endorsed. An NIH consensus panel recommends more transplants but does not say who will pay","volume":"221","author":"Kolata","year":"1983","journal-title":"Science"},{"key":"B6","doi-asserted-by":"publisher","first-page":"50","DOI":"10.31662\/jmaj.2018-0009","article-title":"Present state and future prospects of pediatric liver transplantations","volume":"1","author":"Kasahara","year":"2018","journal-title":"JMA J"},{"key":"B7","doi-asserted-by":"publisher","first-page":"170","DOI":"10.23736\/S1121-421X.17.02452-7","article-title":"Liver allocation","volume":"64","author":"Neuberger","year":"2018","journal-title":"Minerva Gastroenterol Dietol"},{"key":"B8","doi-asserted-by":"publisher","first-page":"1636","DOI":"10.1016\/S0140-6736(99)90002-8","article-title":"Guidelines for selection of patients for liver transplantation in the era of donor-organ shortage","volume":"354","author":"Neuberger","year":"1999","journal-title":"Lancet"},{"key":"B9","doi-asserted-by":"publisher","first-page":"639","DOI":"10.1080\/17474124.2022.2097070","article-title":"Acute-on-chronic liver failure (ACLF) in 2022: have novel treatment paradigms already arrived?","volume":"16","author":"Abbas","year":"2022","journal-title":"Expert Rev Gastroenterol Hepatol"},{"key":"B10","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1111\/j.1749-6632.1975.tb19151.x","article-title":"Current policies in hepatic transplantation: candidacy of patients with alcoholic liver disease or preformed antidonor antibodies and a reappraisal of biliary duct reconstruction","volume":"252","author":"Starzl","year":"1975","journal-title":"Ann N Y Acad Sci"},{"key":"B11","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1002\/hep.1840110202","article-title":"Orthotopic liver transplantation for alcoholic liver disease","volume":"11","author":"Kumar","year":"1990","journal-title":"Hepatology"},{"key":"B12","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1136\/bmj.317.7152.172","article-title":"Assessing priorities for allocation of donor liver grafts: survey of public and clinicians","volume":"317","author":"Neuberger","year":"1998","journal-title":"Br Med J"},{"key":"B13","doi-asserted-by":"publisher","first-page":"262","DOI":"10.1136\/flgastro-2021-101916","article-title":"Twitter debate: controversies in liver transplantation","volume":"13","author":"Tavabie","year":"2022","journal-title":"Frontline Gastroenterol"},{"key":"B14","doi-asserted-by":"publisher","first-page":"1146","DOI":"10.1111\/tri.13655","article-title":"Does publicity affect organ donation?","volume":"33","author":"Madden","year":"2020","journal-title":"Transpl Int"},{"key":"B15","doi-asserted-by":"publisher","first-page":"1790","DOI":"10.1056\/NEJMoa1105703","article-title":"Early liver transplantation for severe alcoholic hepatitis","volume":"365","author":"Mathurin","year":"2011","journal-title":"N Engl J Med"},{"key":"B16","doi-asserted-by":"publisher","first-page":"416","DOI":"10.1016\/S2468-1253(21)00430-1","article-title":"Early liver transplantation for severe alcohol-related hepatitis not responding to medical treatment: a prospective controlled study","volume":"7","author":"Louvet","year":"2022","journal-title":"Lancet Gastroenterol Hepatol"},{"key":"B17","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1002\/hep.32258","article-title":"Liver transplantation for intrahepatic cholangiocarcinoma: ready for prime time?","volume":"75","author":"Sapisochin","year":"2022","journal-title":"Hepatology"},{"key":"B18","doi-asserted-by":"publisher","first-page":"933","DOI":"10.1016\/S2468-1253(21)00219-3","article-title":"Liver transplantation for non-resectable colorectal liver metastases: the international hepato-pancreato-biliary association consensus guidelines","volume":"6","author":"Bonney","year":"2021","journal-title":"Lancet Gastroenterol Hepatol"},{"key":"B19","doi-asserted-by":"publisher","first-page":"3404","DOI":"10.1007\/s00268-021-06248-4","article-title":"Liver transplantation for non-resectable liver metastases from colorectal cancer: a systematic review and meta-analysis","volume":"45","author":"Varley","year":"2021","journal-title":"World J Surg"},{"key":"B20","doi-asserted-by":"publisher","first-page":"1832","DOI":"10.1016\/j.hpb.2022.06.009","article-title":"Treatment strategies for neuroendocrine liver metastases: a systematic review","volume":"24","author":"Muttillo","year":"2022","journal-title":"HPB"},{"key":"B21","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1016\/S0002-9610(99)80095-6","article-title":"Treatment of budd-chiari syndrome with portosystemic shunt or liver transplantation","volume":"171","author":"Hemming","year":"1996","journal-title":"Am J Surg"},{"key":"B22","doi-asserted-by":"publisher","first-page":"147","DOI":"10.14740\/jocmr4724","article-title":"State of the art, current perspectives, and controversies of Budd-Chiari syndrome: a review","volume":"14","author":"Gavriilidis","year":"2022","journal-title":"J Clin Med Res"},{"key":"B23","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1007\/s11908-022-00776-3","article-title":"Advances in liver transplantation for persons with human immunodeficiency infection","volume":"24","author":"Kumar","year":"2022","journal-title":"Curr Infect Dis Rep"},{"key":"B24","doi-asserted-by":"publisher","first-page":"2023","DOI":"10.1111\/ajt.13344","article-title":"Challenges and clinical decision-making in HIV-to-HIV transplantation: insights from the HIV literature","volume":"15","author":"Boyarsky","year":"2015","journal-title":"Am J Transplant"},{"key":"B25","doi-asserted-by":"publisher","first-page":"693","DOI":"10.1056\/NEJM199603143341104","article-title":"Liver transplantation for the treatment of small hepatocellular carcinomas in patients with cirrhosis","volume":"334","author":"Mazzaferro","year":"1996","journal-title":"N Engl J Med"},{"key":"B26","doi-asserted-by":"publisher","first-page":"983","DOI":"10.1002\/bjs.1800770908","article-title":"Primary hepatic malignancy: the role of liver transplantation","volume":"77","author":"Ismail","year":"1990","journal-title":"Br J Surg"},{"key":"B27","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1038\/nrgastro.2016.193","article-title":"Liver transplantation for hepatocellular carcinoma: outcomes and novel surgical approaches","volume":"14","author":"Sapisochin","year":"2017","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"B28","doi-asserted-by":"publisher","first-page":"1394","DOI":"10.1053\/jhep.2001.24563","article-title":"Liver transplantation for hepatocellular carcinoma: expansion of the tumor size limits does not adversely impact survival","volume":"33","author":"Yao","year":"2001","journal-title":"Hepatology"},{"key":"B29","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1053\/j.gastro.2017.09.025","article-title":"Metroticket 2.0 model for analysis of competing risks of death after liver transplantation for hepatocellular carcinoma","volume":"154","author":"Mazzaferro","year":"2018","journal-title":"Gastroenterology"},{"key":"B30","doi-asserted-by":"publisher","first-page":"779","DOI":"10.1001\/jamasurg.2022.2800","article-title":"Ten-year outcomes of liver transplant and downstaging for hepatocellular carcinoma","volume":"157","author":"Tabrizian","year":"2022","journal-title":"JAMA Surg"},{"key":"B31","doi-asserted-by":"publisher","first-page":"947","DOI":"10.1016\/S1470-2045(20)30224-2","article-title":"Liver transplantation in hepatocellular carcinoma after tumour downstaging (XXL): a randomised, controlled, phase 2b\/3 trial","volume":"21","author":"Mazzaferro","year":"2020","journal-title":"Lancet Oncol"},{"key":"B32","doi-asserted-by":"publisher","first-page":"9813","DOI":"10.3390\/curroncol29120771","article-title":"Immunotherapy use prior to liver transplant in patients with hepatocellular carcinoma","volume":"29","author":"Woo","year":"2022","journal-title":"Curr Oncol"},{"key":"B33","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1016\/j.cld.2022.01.011","article-title":"Simultaneous liver-kidney transplantation","volume":"26","author":"Nair","year":"2022","journal-title":"Clin Liver Dis"},{"key":"B34","doi-asserted-by":"publisher","first-page":"1382","DOI":"10.1016\/S0140-6736(84)91876-2","article-title":"Heart-liver transplantation in a patient with familial hypercholesterolaemia","volume":"1","author":"Starzl","year":"1984","journal-title":"Lancet"},{"key":"B35","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1016\/j.trre.2016.07.001","article-title":"Combined heart-liver transplantation: indications, outcomes and current experience","volume":"30","author":"Beal","year":"2016","journal-title":"Transplant Rev"},{"key":"B36","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1111\/j.1399-3046.2012.01695.x","article-title":"Pediatric combined heart-liver transplantation performed en bloc: a single-center experience","volume":"16","author":"Hill","year":"2012","journal-title":"Pediatr Transplant"},{"key":"B37","doi-asserted-by":"publisher","first-page":"2661","DOI":"10.1097\/TP.0000000000003697","article-title":"Operative technique of donor organ procurement for en bloc heart-liver transplantation","volume":"105","author":"Elde","year":"2021","journal-title":"Transplantation"},{"key":"B38","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1016\/j.trre.2018.11.002","article-title":"Combined liver-lung transplantation: indications, outcomes, current experience and ethical issues","volume":"33","author":"Han","year":"2019","journal-title":"Transplant Rev"},{"key":"B39","doi-asserted-by":"publisher","first-page":"1187","DOI":"10.1136\/bmj.2.6045.1187","article-title":"Diagnosis of brain death. Statement issued by the honorary secretary of the conference of medical royal colleges and their faculties in the United Kingdom on 11 October 1976","volume":"2","year":"1976","journal-title":"Br Med J"},{"key":"B40","doi-asserted-by":"publisher","first-page":"1486","DOI":"10.1002\/hep.31152","article-title":"New insights into intestinal failure-associated liver disease in children","volume":"71","author":"Khalaf","year":"2020","journal-title":"Hepatology"},{"key":"B41","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1097\/MOT.0000000000000731","article-title":"Current state of adult intestinal transplantation in Europe","volume":"25","author":"Clarysse","year":"2020","journal-title":"Curr Opin Organ Transplant"},{"key":"B42","doi-asserted-by":"publisher","first-page":"745","DOI":"10.1016\/j.jhep.2018.12.009","article-title":"Age and liver transplantation","volume":"70","author":"Durand","year":"2019","journal-title":"J Hepatol"},{"key":"B43","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1111\/ajt.15674","article-title":"OPTN\/SRTR 2018 annual data report: liver","volume":"20","author":"Kwong","year":"2020","journal-title":"Am J Transplant"},{"key":"B44","doi-asserted-by":"publisher","first-page":"2564","DOI":"10.1002\/hep.31647","article-title":"Cardiac risk assessment in liver transplant candidates: current controversies and future directions","volume":"73","author":"Barman","year":"2021","journal-title":"Hepatology"},{"key":"B45","doi-asserted-by":"publisher","first-page":"318","DOI":"10.1111\/j.1600-6143.2008.02491.x","article-title":"D-MELD, a simple predictor of post liver transplant mortality for optimization of donor\/recipient matching","volume":"9","author":"Halldorson","year":"2009","journal-title":"Am J Transplant"},{"key":"B46","doi-asserted-by":"publisher","first-page":"745","DOI":"10.1097\/SLA.0b013e3182365081","article-title":"Are there better guidelines for allocation in liver transplantation? A novel score targeting justice and utility in the model for end-stage liver disease era","volume":"254","author":"Dutkowski","year":"2011","journal-title":"Ann Surg"},{"key":"B47","doi-asserted-by":"publisher","first-page":"2537","DOI":"10.1111\/j.1600-6143.2008.02400.x","article-title":"Survival outcomes following liver transplantation (SOFT) score: a novel method to predict patient survival following liver transplantation","volume":"8","author":"Rana","year":"2008","journal-title":"Am J Transplant"},{"key":"B48","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1001\/jama.1968.03140320031009","article-title":"A definition of irreversible coma. Report of the ad hoc committee of the harvard medical school to examine the definition of brain death","volume":"205","author":"Auth","year":"1968","journal-title":"J Am Med Assoc"},{"key":"B49","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1097\/00000658-196809000-00009","article-title":"Orthotopic homotransplantation of the human liver","volume":"168","author":"Starzl","year":"1968","journal-title":"Ann Surg"},{"key":"B50","doi-asserted-by":"publisher","first-page":"535","DOI":"10.1136\/bmj.4.5630.535","article-title":"Liver transplantation in man. I. Observations on technique and organization in five cases","volume":"4","author":"Calne","year":"1968","journal-title":"Br Med J"},{"key":"B51","doi-asserted-by":"publisher","first-page":"651","DOI":"10.1053\/jlts.2003.50105","article-title":"The utility of marginal donors in liver transplantation","volume":"9","author":"Busuttil","year":"2003","journal-title":"Liver Transpl"},{"key":"B52","doi-asserted-by":"publisher","first-page":"579","DOI":"10.1067\/msy.2000.108421","article-title":"Liver transplantation from controlled non-heart-beating donors","volume":"128","author":"D'Alessandro","year":"2000","journal-title":"Surgery"},{"key":"B53","doi-asserted-by":"publisher","first-page":"1659","DOI":"10.1097\/01.TP.0000062574.18648.7C","article-title":"Liver transplantation from controlled non-heart-beating donors: an increased incidence of biliary complications","volume":"75","author":"Abt","year":"2003","journal-title":"Transplantation"},{"key":"B54","doi-asserted-by":"publisher","first-page":"274","DOI":"10.1111\/ajt.14429","article-title":"Minimization of ischemic cholangiopathy in donation after cardiac death liver transplantation: is it thrombolytic therapy or warm ischemic time stringency and donor bile duct flush?","volume":"18","author":"Giorgakis","year":"2018","journal-title":"Am J Transplant"},{"key":"B55","doi-asserted-by":"publisher","first-page":"2155","DOI":"10.1111\/ajt.14261","article-title":"Safety and outcomes in 100 consecutive donation after circulatory death liver transplants using a protocol that includes thrombolytic therapy","volume":"17","author":"Bohorquez","year":"2017","journal-title":"Am J Transplant"},{"key":"B56","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1016\/j.ijsu.2020.04.064","article-title":"Donation after circulatory death liver transplantation: what are the limits for an acceptable DCD graft?","author":"Kubal","year":"2020","journal-title":"Int J Surg"},{"key":"B57","doi-asserted-by":"publisher","first-page":"2640","DOI":"10.1097\/TP.0000000000001483","article-title":"Improving national results in liver transplantation using grafts from donation after cardiac death donors","volume":"100","author":"Croome","year":"2016","journal-title":"Transplantation"},{"key":"B58","doi-asserted-by":"publisher","first-page":"855","DOI":"10.1016\/j.jhep.2018.12.033","article-title":"Survival advantage for patients accepting the offer of a circulatory death liver transplant","volume":"70","author":"Taylor","year":"2019","journal-title":"J Hepatol"},{"key":"B59","doi-asserted-by":"publisher","first-page":"1219","DOI":"10.1111\/liv.13404","article-title":"Primary non-function is frequently associated with fatty liver allografts and high mortality after re-transplantation","volume":"37","author":"Kulik","year":"2017","journal-title":"Liver Int"},{"key":"B60","doi-asserted-by":"publisher","first-page":"829","DOI":"10.1002\/hep.1840200410","article-title":"Selecting the donor liver: risk factors for poor function after orthotopic liver transplantation","volume":"20","author":"Strasberg","year":"1994","journal-title":"Hepatology"},{"key":"B61","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1002\/lt.23615","article-title":"Assessment of hepatic steatosis by transplant surgeon and expert pathologist: a prospective, double-blind evaluation of 201 donor livers","volume":"19","author":"Yersiz","year":"2013","journal-title":"Liver Transpl"},{"key":"B62","doi-asserted-by":"publisher","first-page":"1055","DOI":"10.1016\/j.jhep.2010.11.004","article-title":"Liver transplantation using fatty livers: always feasible?","volume":"54","author":"McCormack","year":"2011","journal-title":"J Hepatol"},{"key":"B63","doi-asserted-by":"publisher","first-page":"1612","DOI":"10.1097\/TP.0000000000003062","article-title":"Outcomes after declining a steatotic donor liver for liver transplant candidates in the United States","volume":"104","author":"Jackson","year":"2020","journal-title":"Transplantation"},{"key":"B64","doi-asserted-by":"publisher","first-page":"658","DOI":"10.1016\/j.jhep.2018.12.013","article-title":"Normothermic regional perfusion vs. super-rapid recovery in controlled donation after circulatory death liver transplantation","volume":"70","author":"Hessheimer","year":"2019","journal-title":"J Hepatol"},{"key":"B65","doi-asserted-by":"publisher","first-page":"1156","DOI":"10.1097\/SLA.0000000000005428","article-title":"Liver transplantation outcomes from controlled circulatory death donors: SCS vs in situ NRP vs ex situ NMP","volume":"275","author":"Gaurav","year":"2022","journal-title":"Ann Surg"},{"key":"B66","doi-asserted-by":"publisher","first-page":"1716","DOI":"10.1002\/lt.26522","article-title":"In situ normothermic regional perfusion versus ex situ normothermic machine perfusion in liver transplantation from donation after circulatory death","volume":"28","author":"Mohkam","year":"2022","journal-title":"Liver Transpl"},{"key":"B67","doi-asserted-by":"publisher","first-page":"10460","DOI":"10.3389\/ti.2022.10460","article-title":"Normothermic machine perfusion-improving the supply of transplantable livers for high-risk recipients","volume":"35","author":"Hann","year":"2022","journal-title":"Transpl Int"},{"key":"B68","doi-asserted-by":"crossref","DOI":"10.1093\/bjs\/znab475","article-title":"Outcomes of normothermic machine perfusion of liver grafts in repeat liver transplantation (the NAPLES initiative)","author":"Hann","year":"2022","journal-title":"Br J Surg"},{"key":"B69","doi-asserted-by":"publisher","first-page":"1391","DOI":"10.1056\/NEJMoa2031532","article-title":"Hypothermic machine perfusion in liver transplantation: a randomized trial","volume":"384","author":"van Rijn","year":"2021","journal-title":"N Engl J Med"},{"key":"B70","doi-asserted-by":"publisher","first-page":"32","DOI":"10.5662\/wjm.v12.i1.32","article-title":"Liver transplant allocation policies and outcomes in United States: a comprehensive review","volume":"12","author":"Latt","year":"2022","journal-title":"World J Methodol"},{"key":"B71","doi-asserted-by":"publisher","first-page":"e00763","DOI":"10.14309\/crj.0000000000000763","article-title":"The evolution of the MELD score and its implications in liver transplant allocation: a beginner\u2019s guide for trainees","volume":"9","author":"Trivedi","year":"2022","journal-title":"ACG Case Rep J"},{"key":"B72","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1097\/MOT.0000000000000743","article-title":"Development of a UK liver transplantation selection and allocation scheme","volume":"25","author":"Gimson","year":"2020","journal-title":"Curr Opin Organ Transplant"},{"key":"B73","doi-asserted-by":"publisher","first-page":"469","DOI":"10.1097\/TP.0b013e318225db4d","article-title":"Elective liver transplant list mortality: development of a United Kingdom end-stage liver disease score","volume":"92","author":"Barber","year":"2011","journal-title":"Transplantation"},{"key":"B74","year":""},{"key":"B75","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1136\/flgastro-2019-101215","article-title":"Adult liver transplantation: a UK clinical guideline - part 1: pre-operation","volume":"11","author":"Millson","year":"2020","journal-title":"Frontline Gastroenterol"},{"key":"B76","doi-asserted-by":"publisher","first-page":"830","DOI":"10.4254\/wjh.v13.i8.830","article-title":"Evolution of liver transplant organ allocation policy: current limitations and future directions","volume":"13","author":"Polyak","year":"2021","journal-title":"World J Hepatol"},{"key":"B77","doi-asserted-by":"publisher","first-page":"843","DOI":"10.1016\/j.jhep.2015.11.015","article-title":"Liver transplant center variability in accepting organ offers and its impact on patient survival","volume":"64","author":"Goldberg","year":"2016","journal-title":"J Hepatol"},{"key":"B78","doi-asserted-by":"publisher","first-page":"1284","DOI":"10.1080\/13696998.2020.1804391","article-title":"Cost-utility analysis of normothermic liver perfusion with the OrganOx metra compared to static cold storage in the United Kingdom","volume":"23","author":"Javanbakht","year":"2020","journal-title":"J Med Econ"},{"key":"B79","article-title":"The national academies collection: reports funded by national institutes of health","volume-title":"Realizing the promise of equity in the organ transplantation system","author":"Hackmann","year":"2022"},{"key":"B80","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1097\/TP.0000000000004464","article-title":"Achieving equity in organ transplantation: recommendations for action based on the national academies of sciences, engineering, and medicine report","volume":"107","author":"Dageforde","year":"2022","journal-title":"Transplantation"}],"container-title":["Frontiers in Transplantation"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/frtra.2023.1178452\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,3]],"date-time":"2023-07-03T07:30:57Z","timestamp":1688369457000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/frtra.2023.1178452\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,3]]},"references-count":80,"alternative-id":["10.3389\/frtra.2023.1178452"],"URL":"https:\/\/doi.org\/10.3389\/frtra.2023.1178452","relation":{},"ISSN":["2813-2440"],"issn-type":[{"value":"2813-2440","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,7,3]]},"article-number":"1178452"}}