{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T09:59:41Z","timestamp":1784627981065,"version":"3.55.0"},"reference-count":18,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T00:00:00Z","timestamp":1766016000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Transplant."],"abstract":"<jats:p>Recent changes to allocation systems have increased the geographic distribution of pancreas offers, often originating from outside a transplant center's donor service area or region. The impact of this wider sharing on outcomes remains uncertain. This study analyzed outcomes of primary pancreas transplants (2000\u20132018) at a large transplant center, stratified retrospectively on the nautical miles distance from the donor hospital. Primary endpoints were death-censored graft survival (DC-GS), patient survival, and graft thrombosis at different time points. No significant differences were found in DC-GS or patient survival for recipients of simultaneous pancreas-kidney (SPK), pancreas after kidney (PAK), or pancreas transplant alone (PTA), regardless of the distance from the donor hospital to the transplant center. Thrombosis rates were comparable across groups. Imported pancreata were from younger donors with lower BMI compared to locally recovered grafts. These findings support the notion that importing pancreata for transplantation is a feasible and safe practice that benefits patients, increases organ utilization, while benefiting transplant center volume data and reducing waiting times for patients. Encouraging wider importation may reduce waiting times and improve access to pancreas transplantation.<\/jats:p>","DOI":"10.3389\/frtra.2025.1698617","type":"journal-article","created":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T06:44:42Z","timestamp":1766040282000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Importing pancreata for transplantation: a single-center experience across evolving allocation eras"],"prefix":"10.3389","volume":"4","author":[{"given":"Riccardo","family":"Tamburrini","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stacey","family":"Hidalgo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Glen","family":"Leverson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dixon B.","family":"Kaufman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikole A.","family":"Neidlinger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David P.","family":"Al-Adra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David D.","family":"Aufhauser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carrie","family":"Thiessen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Didier","family":"Mandelbrot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandesh","family":"Parajuli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jon S.","family":"Odorico","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2025,12,18]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"2810","DOI":"10.1111\/ajt.16462","article-title":"Single center results of simultaneous pancreas-kidney transplantation in patients with type 2 diabetes","volume":"21","author":"Pham","year":"2021","journal-title":"Am J Transplant"},{"key":"B2","doi-asserted-by":"publisher","first-page":"823","DOI":"10.1111\/ajt.15106","article-title":"The survival advantage of pancreas after kidney transplant","volume":"19","author":"Fridell","year":"2019","journal-title":"Am J Transplant"},{"key":"B3","doi-asserted-by":"publisher","first-page":"2018","DOI":"10.1111\/j.1600-6143.2004.00667.x","article-title":"Mortality assessment for pancreas transplants","volume":"4","author":"Gruessner","year":"2004","journal-title":"Am J Transplant"},{"key":"B4","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1016\/j.gtc.2015.10.008","article-title":"Pancreas transplantation in the modern era","volume":"45","author":"Redfield","year":"2016","journal-title":"Gastroenterol Clin North Am"},{"key":"B5","doi-asserted-by":"publisher","first-page":"723","DOI":"10.1097\/TP.0b013e3181b2a01b","article-title":"No difference in transplant outcomes for local and import pancreas allografts","volume":"88","author":"Fridell","year":"2009","journal-title":"Transplantation"},{"key":"B6","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1007\/s40472-014-0015-8","article-title":"Expanding the pancreas donor pool","volume":"1","author":"Fridell","year":"2014","journal-title":"Curr Transplant Rep"},{"key":"B7","doi-asserted-by":"publisher","first-page":"622","DOI":"10.1097\/TP.0b013e3181b22db3","article-title":"Import pancreas allografts: good from far or far from good?","volume":"88","author":"Stratta","year":"2009","journal-title":"Transplantation"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1111\/ctr.13154","article-title":"Improving pancreas graft utilization through importation","volume":"32","author":"Torabi","year":"2018","journal-title":"Clin Transplant"},{"key":"B9","doi-asserted-by":"publisher","first-page":"1103","DOI":"10.1097\/TP.0000000000001125","article-title":"Virtual HLA crossmatching as a means to safely expedite transplantation of imported pancreata","volume":"100","author":"Eby","year":"2016","journal-title":"Transplantation"},{"key":"B10","doi-asserted-by":"publisher","first-page":"3124","DOI":"10.1111\/ajt.15387","article-title":"Isolated pancreas transplantation: is rank list position related to outcomes of imported grafts?","volume":"19","author":"Adler","year":"2019","journal-title":"Am J Transplant"},{"key":"B11","doi-asserted-by":"publisher","first-page":"1546","DOI":"10.1681\/ASN.2020121679","article-title":"New kidney and pancreas allocation policy: moving to a circle as the first unit of allocation","volume":"32","author":"Israni","year":"2021","journal-title":"J Am Soc Nephrol"},{"key":"B12","doi-asserted-by":"publisher","first-page":"447","DOI":"10.1111\/j.1600-6143.2011.03828.x","article-title":"Comparison of recipient outcomes following transplant from local versus imported pancreas donors","volume":"12","author":"Finger","year":"2012","journal-title":"Am J Transplant"},{"key":"B13","doi-asserted-by":"publisher","first-page":"1257","DOI":"10.1016\/j.ajt.2024.03.006","article-title":"Impact of removing donation service area and region from pancreas allocation","volume":"24","author":"Booker","year":"2024","journal-title":"Am J Transplant"},{"key":"B14","doi-asserted-by":"publisher","first-page":"e15061","DOI":"10.1111\/ctr.15061","article-title":"When pancreata fly: outcomes and lessons learned from the development of a pancreas transplant import program","volume":"37","author":"Owen-Simon","year":"2023","journal-title":"Clin Transplant"},{"key":"B15","doi-asserted-by":"publisher","first-page":"810","DOI":"10.1111\/tri.12754","article-title":"Pancreas transplantation in older patients is safe, but patient selection is paramount","volume":"29","author":"Scalea","year":"2016","journal-title":"Transpl Int"},{"key":"B16","doi-asserted-by":"publisher","first-page":"e13337","DOI":"10.1111\/ctr.13337","article-title":"Ipsilateral versus contralateral placement of the pancreas allograft in pancreas after kidney transplant recipients","volume":"32","author":"Yin","year":"2018","journal-title":"Clin Transplant"},{"key":"B17","doi-asserted-by":"publisher","first-page":"e1402","DOI":"10.1097\/TXD.0000000000001402","article-title":"Induction in pancreas transplantation: t-cell depletion versus IL-2 receptor blockade","volume":"8","author":"Aziz","year":"2022","journal-title":"Transplant Direct"},{"key":"B18","doi-asserted-by":"publisher","first-page":"2305","DOI":"10.1016\/j.transproceed.2017.10.006","article-title":"The pancreas can take the cold: lower waitlist times through importation","volume":"49","author":"Choinski","year":"2017","journal-title":"Transplant Proc"}],"container-title":["Frontiers in Transplantation"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/frtra.2025.1698617\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T06:44:43Z","timestamp":1766040283000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/frtra.2025.1698617\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,18]]},"references-count":18,"alternative-id":["10.3389\/frtra.2025.1698617"],"URL":"https:\/\/doi.org\/10.3389\/frtra.2025.1698617","relation":{},"ISSN":["2813-2440"],"issn-type":[{"value":"2813-2440","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,18]]},"article-number":"1698617"}}