{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T00:45:07Z","timestamp":1791852307274,"version":"4.3.4"},"reference-count":21,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2024,6,3]],"date-time":"2024-06-03T00:00:00Z","timestamp":1717372800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Urol."],"abstract":"<jats:p>Spindle cell lipoma is a relatively rare benign tumor that can occur in the posterior neck, shoulder, and upper back. Herein, we present a case of intrascrotal spindle cell lipoma in a 71-year-old male who presented with a mass in the left scrotum that had developed over 2 years. Contrast-enhanced computed tomography (CT) revealed a 5.7cm mass accompanying enhanced solid components. Magnetic resonance imaging (MRI) showed a heterogeneous signal intensity. Therefore, a well-differentiated liposarcoma derived from the spermatic cord was suspected; therefore, the patient underwent radical inguinal orchidectomy with high ligation of the spermatic cord. Histopathological examination revealed mature adipocytes and bland-spindle cells. Immunohistochemically, the tumor cells were positive for CD-34 and negative for CDK4, MDM2, and p16. These findings indicated a spindle cell lipoma. Surgical margins were negative. Three months after surgery, no relapse was observed. This case underscores the rarity of para-testicular spindle cell lipoma. While CT and MRI play crucial roles in disease diagnosis, they may not detect all lesions. To prevent overtreatment, it\u2019s essential to also consider pre-surgical examinations and intraoperative findings.<\/jats:p>","DOI":"10.3389\/fruro.2024.1400674","type":"journal-article","created":{"date-parts":[[2024,6,3]],"date-time":"2024-06-03T05:10:12Z","timestamp":1717391412000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Case report: Para-testicular spindle cell lipoma suspected of well-differentiated liposarcoma"],"prefix":"10.3389","volume":"4","author":[{"given":"Kengo","family":"Fujiwara","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kengo","family":"Fujimoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emi","family":"Ibuki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryo","family":"Ishikawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yushi","family":"Hayashida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2024,6,3]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1111\/andr.13021","article-title":"Paratesticular lesions: Aetiology and appearances on ultrasound","volume":"9","author":"Rafailidis","year":"2021","journal-title":"Andrology"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1148\/rg.236025174","article-title":"Multimodality imaging of paratesticular neoplasms and their rare mimics","volume":"23","author":"Akbar","year":"2003","journal-title":"Radiographics"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1016\/j.urolonc.2013.08.009","article-title":"Primary spermatic cord tumors: disease characteristics, prognostic factors, and treatment outcomes","volume":"32","author":"Rodr\u00edguez","year":"2014","journal-title":"Urol Oncol"},{"key":"B4","doi-asserted-by":"publisher","first-page":"1886","DOI":"10.1038\/s41598-022-05752-4","article-title":"Accuracy of core needle biopsy for histologic diagnosis of soft tissue sarcoma","volume":"12","author":"Kiefer","year":"2022","journal-title":"Sci Rep"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1097\/GOX.0000000000004462","article-title":"Comprehensive review of reported nonclassical spindle cell lipoma presentations and a unique case report","volume":"10","author":"Engwall-Gill","year":"2022","journal-title":"Plast Reconstr Surg Glob Open"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.21037\/tau.2019.12.20","article-title":"Radical inguinal orchidectomy: the gold standard for initial management of testicular cancer","volume":"9","author":"Koschel","year":"2020","journal-title":"Transl Androl Urol"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.21873\/cdp.10213","article-title":"Spindle cell lipoma, and pleomorphic lipoma: an update and review","volume":"3","author":"Ohshima","year":"2023","journal-title":"Cancer Diagn Progn"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.3390\/cancers15112985","article-title":"CT and MR imaging of retroperitoneal sarcomas: a practical guide for the radiologist","volume":"15","author":"Porrello","year":"2023","journal-title":"Cancers (Basel)"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197511)36:5<1852::AID-CNCR2820360542>3.0.CO;2-U","article-title":"Spindle cell lipoma","volume":"36","author":"Enzinger","year":"1975","journal-title":"Cancer"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.5980\/jpnjurol.111.102","article-title":"A case of spindle cell lipoma arising in the inguinal subcutis: a case report","volume":"111","author":"Sasaki","year":"2020","journal-title":"Nihon Hinyokika Gakkai Zasshi"},{"key":"B11","doi-asserted-by":"publisher","first-page":"7903242","DOI":"10.1155\/2017\/7903242","article-title":"Rare case of a well-differentiated paratesticular sarcoma of the spermatic cord in a 60-year-old patient","volume":"2017","author":"Benna","year":"2017","journal-title":"Case Rep Urol"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.20471\/acc.2021.60.01.07","article-title":"Liposarcoma of the spermatic cord - 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