{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T05:02:57Z","timestamp":1784782977372,"version":"3.55.0"},"reference-count":33,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T00:00:00Z","timestamp":1784764800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Stroke"],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Stroke has become the third leading cause of death, accounting for 10% of all deaths. The prevalence of intracranial hemorrhage, subarachnoid hemorrhage, and ischemic stroke has increased by 20.5%, 11.5%, and 7.4%, respectively, in the 20\u201354 age group, making it a worldwide problem for the young adult population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To describe the clinical characteristics, diagnostic findings, stroke subtypes, and frequent risk factors among young adult patients with stroke treated at a tertiary care hospital in Honduras.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Cross-sectional, non-probability convenience sample study of 70 patients aged 18\u201355 years. An ethical opinion was obtained (079-2024). The information was supplemented with clinical examinations, laboratory tests, neuroimaging, carotid Doppler, and transcranial Doppler with bubble test. Descriptive statistics were obtained.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Young adults accounted for 30.0% of stroke cases evaluated. The mean age was 43.4 \u00b1 9.1 years. The 61.4% were women, 55.7% had a history of hypertension, 31.4% had type 2 diabetes mellitus, and 24.3% had migraines. A total of 21.4% were smokers, and 15.7% of women used oral contraceptives. Ischemic stroke occurred in 71.4% of cases, with a cardioembolic etiology in 21.4%. A patent foramen ovale (PFO) was identified in 5 of 17 cases, corresponding to 29.4% of the tested subgroup and 7.1% of the total sample and mortality was 15.7%.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>A high proportion of strokes were observed in women, with a predominance of ischemic strokes of cardioembolic etiology. Modifiable factors associated with stroke were identified, which can be controlled, contributing to a decrease in morbidity and mortality from this pathology.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fstro.2026.1887056","type":"journal-article","created":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T04:28:15Z","timestamp":1784780895000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Clinical characteristics and frequent risk factors in young adult patients with stroke at a tertiary care hospital in Honduras"],"prefix":"10.3389","volume":"5","author":[{"given":"Kivian Obed","family":"Matamoros Padilla","sequence":"first","affiliation":[{"name":"Postgraduate Program of Neurology, Faculty of Medical Sciences, National Autonomous University of Honduras (UNAH)","place":["Tegucigalpa, Honduras"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto Daniel","family":"Padilla Valeriano","sequence":"additional","affiliation":[{"name":"Postgraduate Program of Neurology, Faculty of Medical Sciences, National Autonomous University of Honduras (UNAH)","place":["Tegucigalpa, Honduras"]},{"name":"Department of Internal Medicine, Faculty of Medical Sciences, National Autonomous University of Honduras (UNAH)","place":["Tegucigalpa, Honduras"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eleonora","family":"Espinoza-Turcio","sequence":"additional","affiliation":[{"name":"Faculty of Medical Sciences, National Autonomous University of Honduras (UNAH)","place":["Tegucigalpa, Honduras"]},{"name":"Group GRINVAR, Faculty of Medical Sciences (FCM), National Autonomous University of Honduras (UNAH)","place":["Tegucigalpa, Honduras"]},{"name":"Mental Health Research Group, Faculty of Medical Sciences (FCM), National Autonomous University of Honduras (UNAH)","place":["Tegucigalpa, Honduras"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henry Noel","family":"Castro-Ramos","sequence":"additional","affiliation":[{"name":"Faculty of Medical Sciences, National Autonomous University of Honduras (UNAH)","place":["Tegucigalpa, Honduras"]},{"name":"Group GRINVAR, Faculty of Medical Sciences (FCM), National Autonomous University of Honduras (UNAH)","place":["Tegucigalpa, Honduras"]},{"name":"Mental Health Research Group, Faculty of Medical Sciences (FCM), National Autonomous University of Honduras (UNAH)","place":["Tegucigalpa, Honduras"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lysien Ivania","family":"Zambrano","sequence":"additional","affiliation":[{"name":"Faculty of Medical Sciences, National Autonomous University of Honduras (UNAH)","place":["Tegucigalpa, Honduras"]},{"name":"Group GRINVAR, Faculty of Medical Sciences (FCM), National Autonomous University of Honduras (UNAH)","place":["Tegucigalpa, Honduras"]},{"name":"Mental Health Research Group, Faculty of Medical Sciences (FCM), National Autonomous University of Honduras (UNAH)","place":["Tegucigalpa, Honduras"]},{"name":"Department of Morphological Sciences, Faculty of Medical Sciences (FCM), National Autonomous University of Honduras (UNAH)","place":["Tegucigalpa, Honduras"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Selvin Z.","family":"Reyes-Garcia","sequence":"additional","affiliation":[{"name":"Faculty of Medical Sciences, National Autonomous University of Honduras (UNAH)","place":["Tegucigalpa, Honduras"]},{"name":"Department of Morphological Sciences, Faculty of Medical Sciences (FCM), National Autonomous University of Honduras (UNAH)","place":["Tegucigalpa, Honduras"]},{"name":"Faculty of Medical Sciences (FCM), Institute for Research in Medical Sciences and Health Rights (ICIMEDES), National Autonomous University of Honduras (UNAH)","place":["Tegucigalpa, Honduras"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,7,23]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"639","DOI":"10.1007\/s10072-020-04584-2","article-title":"Ischemic stroke in young adults in Bogota, Colombia: a cross-sectional study","volume":"42","author":"Aguilera-Pena","year":"2021","journal-title":"Neurol. 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