{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T09:29:08Z","timestamp":1778232548324,"version":"3.51.4"},"reference-count":18,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2021,5,25]],"date-time":"2021-05-25T00:00:00Z","timestamp":1621900800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Surg."],"abstract":"<jats:p><jats:bold>Background:<\/jats:bold> Meckel diverticulum (MD) is the most common congenital anomaly of the intestines, with an incidence of 2% of the general population. It can present as various clinical features with complications and be life threatening if diagnosis is delayed and treatment late.<\/jats:p><jats:p><jats:bold>Case Presentation:<\/jats:bold> We report three pediatric cases with complicated MD: one female presented with small-bowel obstruction, one male with peritonitis, and one female with severe iron-deficiency anemia, without gross gastrointestinal bleeding nor any ectopic gastric mucosa. All patients underwent exploratory laparotomy, segmental small-bowel resection, and primary anastomosis. They successfully recovered and were uneventfully discharged on the fourth, seventh, and 10th postoperative days, respectively.<\/jats:p><jats:p><jats:bold>Conclusions:<\/jats:bold> MD can present with various complication spectrums, including small-bowel obstruction, peritonitis, and severe iron-deficiency anemia, which may cause difficulty in definitive diagnosis, particularly in children. Segmental small-bowel resection and primary anastomosis are effective surgical approaches and show good outcomes for MD patients.<\/jats:p>","DOI":"10.3389\/fsurg.2021.674382","type":"journal-article","created":{"date-parts":[[2021,5,25]],"date-time":"2021-05-25T04:30:14Z","timestamp":1621917014000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":4,"title":["Case Report: Complicated Meckel Diverticulum Spectrum in Children"],"prefix":"10.3389","volume":"8","author":[{"family":"Gunadi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wahyu","family":"Damayanti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robin Perdana","family":"Saputra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Ramadhita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ibnu Sina","family":"Ibrohim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andi","family":"Lestiono","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Devy","family":"Melati","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Winda Intan","family":"Permatahati","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Titis","family":"Widowati","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akhmad","family":"Makhmudi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2021,5,25]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"e12154","DOI":"10.1097\/MD.0000000000012154","article-title":"Systematic review of epidemiology, presentation, and management of Meckel's diverticulum in the 21st century","volume":"97","author":"Hansen","year":"2018","journal-title":"Medicine (Baltimore)."},{"key":"B2","doi-asserted-by":"publisher","first-page":"e100114","DOI":"10.7363\/100114","article-title":"Symptomatic Meckel's diverticulum in children: a 12-year survey","volume":"10","author":"Fonseca","year":"2021","journal-title":"J Pediatr Neonat Individual Med."},{"key":"B3","doi-asserted-by":"publisher","first-page":"199","DOI":"10.3109\/15513815.2016.1161684","article-title":"Pediatric Meckel's diverticulum: report of 208 cases and review of the literature","volume":"35","author":"Francis","year":"2016","journal-title":"Fetal Pediatr Pathol."},{"key":"B4","doi-asserted-by":"publisher","first-page":"649","DOI":"10.1007\/s00383-014-3513-y","article-title":"Demographic disparities of children presenting with symptomatic Meckel's diverticulum in children's hospitals","volume":"30","author":"Alemayehu","year":"2014","journal-title":"Pediatr Surg Int."},{"key":"B5","doi-asserted-by":"publisher","first-page":"893","DOI":"10.1016\/j.jpedsurg.2011.02.024","article-title":"National trends in the surgical management of Meckel's diverticulum","volume":"46","author":"Ruscher","year":"2011","journal-title":"J Pediatr Surg."},{"key":"B6","doi-asserted-by":"publisher","first-page":"267","DOI":"10.3389\/fped.2019.00267","article-title":"Symptomatic Meckel's diverticulum in pediatric patients-case reports and systematic review of the literature","volume":"7","author":"Keese","year":"2019","journal-title":"Front Pediatr."},{"key":"B7","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1007\/s12245-010-0213-9","article-title":"Perforated Meckel diverticulum","volume":"3","author":"Kloss","year":"2010","journal-title":"Int J Emerg Med."},{"key":"B8","doi-asserted-by":"publisher","first-page":"3","DOI":"10.4103\/1319-3767.58760","article-title":"Meckel's diverticulum-revisited","volume":"16","author":"Malik","year":"2010","journal-title":"Saudi J Gastroenterol."},{"key":"B9","unstructured":"Meckel's diverticulum. In: Holzheimer RG, Mannick JA, editors\n            StallionA\n            ShuckJM\n          Surgical Treatment: Evidence-Based and Problem-Oriented2001"},{"key":"B10","doi-asserted-by":"publisher","first-page":"30","DOI":"10.21699\/jns.v5i3.351","article-title":"Vitellointestinal duct anomalies in infancy","volume":"5","author":"Kadian","year":"2016","journal-title":"J Neonatal Surg."},{"key":"B11","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1016\/j.ijscr.2017.08.037","article-title":"A rare case report of patent vitellointestinal duct causing bowel obstruction in an adult","volume":"39","author":"Bhandari","year":"2017","journal-title":"Int J Surg Case Rep."},{"key":"B12","doi-asserted-by":"publisher","first-page":"6155","DOI":"10.3748\/wjg.v18.i42.6155","article-title":"Inverted Meckel's diverticulum as a cause of occult lower gastrointestinal hemorrhage","volume":"18","author":"Rashid","year":"2012","journal-title":"World J Gastroenterol."},{"key":"B13","doi-asserted-by":"publisher","first-page":"319","DOI":"10.11604\/pamj.2015.20.319.5980","article-title":"Spontaneous perforation of Meckel's diverticulum: a case report and review of literature","volume":"20","author":"Farah","year":"2015","journal-title":"Pan Afr Med J."},{"key":"B14","first-page":"826","article-title":"Meckel's diverticulitis causing intestinal obstruction in a 3 month old infant","volume":"18","author":"Kumar","year":"2013","journal-title":"J Res Med Sci."},{"key":"B15","doi-asserted-by":"publisher","first-page":"228","DOI":"10.4103\/1319-3767.65180","article-title":"Correspondence to paper by Malik A: \u201cMeckel's diverticulum-revisited\u201d","volume":"16","author":"Beyazit","year":"2010","journal-title":"Saudi J Gastroenterol."},{"key":"B16","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1136\/gut.2006.097063","article-title":"Editor's quiz: iron deficiency anaemia 10 years after small bowel resection in infancy","volume":"56","author":"Weersma","year":"2007","journal-title":"Gut."},{"key":"B17","doi-asserted-by":"publisher","first-page":"1549","DOI":"10.12669\/pjms.312.6462","article-title":"Disorders associated with malabsorption of iron: a critical review","volume":"31","author":"Saboor","year":"2015","journal-title":"Pak J Med Sci."},{"key":"B18","doi-asserted-by":"publisher","first-page":"1610","DOI":"10.1016\/j.jpedsurg.2017.03.047","article-title":"Optimizing surgical resection of the bleeding Meckel diverticulum in children","volume":"52","author":"Robinson","year":"2017","journal-title":"J Pediatr Surg."}],"container-title":["Frontiers in Surgery"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fsurg.2021.674382\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,25]],"date-time":"2021-05-25T04:30:20Z","timestamp":1621917020000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fsurg.2021.674382\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5,25]]},"references-count":18,"alternative-id":["10.3389\/fsurg.2021.674382"],"URL":"https:\/\/doi.org\/10.3389\/fsurg.2021.674382","relation":{},"ISSN":["2296-875X"],"issn-type":[{"value":"2296-875X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,5,25]]},"article-number":"674382"}}