{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T11:43:12Z","timestamp":1781610192426,"version":"3.54.5"},"reference-count":17,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2021,7,19]],"date-time":"2021-07-19T00:00:00Z","timestamp":1626652800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Surg."],"abstract":"<jats:p>Contrast-induced encephalopathy (CIE) is a rare complication of endovascular treatment and is extensively reported as a transient and reversible phenomenon. This report describes a 62-year-old woman for embolization of an internal carotid artery (ICA) aneurysm. The operation was successful, but postoperation the patient suffered unconsciousness, blindness, hemiplegia, ophthalmoplegia, fever, and seizures. CT of the brain without the contrast showed widespread edema in the right cerebral hemisphere, which is involved in the frontal, parietal, temporal, and occipital lobes. She was diagnosed with CIE in time and treated with supportive management as soon as possible, and fortunately, the patient improved a benign course and was discharged without any neurological deficits. This study emphasizes the prevention of the CIE and the importance of early diagnosis and symptomatic treatment.<\/jats:p>","DOI":"10.3389\/fsurg.2021.689713","type":"journal-article","created":{"date-parts":[[2021,7,19]],"date-time":"2021-07-19T10:16:48Z","timestamp":1626689808000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":3,"title":["Case Report: A 62-Year-Old Woman With Contrast-Induced Encephalopathy Caused by Embolization of Intracranial Aneurysm"],"prefix":"10.3389","volume":"8","author":[{"given":"Ying","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pengfei","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yumin","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ping","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2021,7,19]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1212\/WNL.20.4.353","article-title":"Transient cortical blindness. An unusual complication of coronary angiography","volume":"20","author":"Fischer-Williams","year":"1970","journal-title":"Neurology."},{"key":"B2","doi-asserted-by":"publisher","first-page":"545","DOI":"10.1583\/11-3476C.1","article-title":"Commentary: New insights into the risk factors of contrast-induced encephalopathy","volume":"18","author":"Yu","year":"2011","journal-title":"J Endovasc Ther."},{"key":"B3","doi-asserted-by":"publisher","first-page":"603","DOI":"10.3174\/ajnr.A0858","article-title":"Cortical blindness, transient and otherwise, associated with detachable coil embolization of intracranial aneurysms","volume":"29","author":"Niimi","year":"2008","journal-title":"AJNR Am J Neuroradiol."},{"key":"B4","doi-asserted-by":"publisher","first-page":"629","DOI":"10.2169\/internalmedicine.5139-20","article-title":"Low-dose contrast-induced encephalopathy during diagnostic cerebral angiography","volume":"60","author":"Kamimura","year":"2021","journal-title":"Intern Med."},{"key":"B5","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1177\/159101991201800105","article-title":"Persistent neurological deficit from iodinated contrast encephalopathy following intracranial aneurysm coiling. A case report and review of the literature","volume":"18","author":"Leong","year":"2012","journal-title":"Interv Neuroradiol."},{"key":"B6","doi-asserted-by":"publisher","first-page":"34","DOI":"10.2176\/nmc.53.34","article-title":"Repeated injection of contrast medium inducing dysfunction of the blood-brain barrier: case report","volume":"53","author":"Iwata","year":"2013","journal-title":"Neurol Med Chir (Tokyo)."},{"key":"B7","doi-asserted-by":"publisher","first-page":"567","DOI":"10.1212\/WNL.39.4.567","article-title":"Cortical blindness due to osmotic disruption of the blood-brain barrier by angiographic contrast material: CT and MRI studies","volume":"39","author":"Lantos","year":"1989","journal-title":"Neurology."},{"key":"B8","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1002\/ccd.26871","article-title":"Contrast-induced encephalopathy following cardiac catheterization","volume":"90","author":"Spina","year":"2017","journal-title":"Catheter Cardiovasc Interv."},{"key":"B9","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1007\/s10072-011-0765-3","article-title":"Transient contrast encephalopathy after carotid angiography mimicking diffuse subarachnoid haemorrhage","volume":"33","author":"Potsi","year":"2012","journal-title":"Neurol Sci."},{"key":"B10","doi-asserted-by":"publisher","first-page":"641","DOI":"10.2176\/nmc.oa.2017-0132","article-title":"Contrast-induced encephalopathy following embolization of intracranial aneurysms in hemodialysis patients","volume":"57","author":"Matsubara","year":"2017","journal-title":"Neurol Med Chir (Tokyo)."},{"key":"B11","doi-asserted-by":"publisher","first-page":"9278526","DOI":"10.1155\/2018\/9278526","article-title":"A seizure and hemiplegia following contrast exposure: understanding contrast-induced encephalopathy","volume":"2018","author":"Donepudi","year":"2018","journal-title":"Case Rep Med."},{"key":"B12","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1186\/s12883-019-1279-5","article-title":"Irreversible fatal contrast-induced encephalopathy: a case report","volume":"19","author":"Zhao","year":"2019","journal-title":"BMC Neurol."},{"key":"B13","doi-asserted-by":"publisher","first-page":"845","DOI":"10.1056\/NEJM198710013171401","article-title":"Pretreatment with corticosteroids to alleviate reactions to intravenous contrast material","volume":"317","author":"Lasser","year":"1987","journal-title":"N Engl J Med."},{"key":"B14","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1016\/S0272-6386(97)90568-0","article-title":"Endothelin and atrial natriuretic peptide levels following radiocontrast exposure in humans","volume":"30","author":"Clark","year":"1997","journal-title":"Am J Kidney Dis."},{"key":"B15","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1136\/practneurol-2018-001986","article-title":"Cerebral catheter angiography and its complications","volume":"18","author":"Alakbarzade","year":"2018","journal-title":"Pract Neurol."},{"key":"B16","doi-asserted-by":"publisher","first-page":"542","DOI":"10.3390\/nano9040542","article-title":"Contrast agents delivery: an Up-to-date review of nanodiagnostics in neuroimaging","volume":"9","author":"Teleanu","year":"2019","journal-title":"Nanomaterials (Basel)"},{"key":"B17","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1967\/s002449910558","article-title":"Enhancing contrast agents and radiotracers performance through hyaluronic acid-coating in neuroradiology and nuclear medicine","volume":"20","author":"Ganau","year":"2017","journal-title":"J Nucl. Med."}],"container-title":["Frontiers in Surgery"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fsurg.2021.689713\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,19]],"date-time":"2021-07-19T10:16:50Z","timestamp":1626689810000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fsurg.2021.689713\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7,19]]},"references-count":17,"alternative-id":["10.3389\/fsurg.2021.689713"],"URL":"https:\/\/doi.org\/10.3389\/fsurg.2021.689713","relation":{},"ISSN":["2296-875X"],"issn-type":[{"value":"2296-875X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,7,19]]},"article-number":"689713"}}