{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T08:37:47Z","timestamp":1769503067769,"version":"3.49.0"},"reference-count":29,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,1,21]],"date-time":"2022-01-21T00:00:00Z","timestamp":1642723200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100015951","name":"Qinghai Provincial Key Laboratory of Tibetan Medicine Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100015951","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Surg."],"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To retrospectively analyze the effects of radical lesion resection and quasi radical lesion resection on the quality of life of patients with advanced hepatic alveolar echinococcosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Through the existing HIS system of Qinghai Provincial People's Hospital, 104 patients with hepatic alveolar echinococcosis who underwent surgical treatment in our hospital from January 2012 to December 2017 and completed the quality of life questionnaire were selected as the research objects. The above cases were divided into radical group (<jats:italic>n<\/jats:italic> = 51) and quasi-radical group (<jats:italic>n<\/jats:italic> = 53) according to different surgical methods (degree of radical cure). The quality of life of patients with hydatidosis was measured by interview or telephone follow-up. The preoperative indexes, intraoperative conditions and postoperative recovery indicators of the two groups were observed, such as Child-Puhg grade, PNM classification, scope of hepatectomy, intraoperative bleeding, Clavien grade, incidence of complications, 5-year recurrence rate and total score of quality of life and so on.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There was no significant difference between the two groups in general data such as age, gender, hydatid size, Child-Puhg grade and preoperative liver function (<jats:italic>P<\/jats:italic> &amp;gt; 0.05). However, there was a statistically significant difference in PNM classification between the two groups (<jats:italic>P<\/jats:italic> &amp;lt; 0.05). There were significant differences in intraoperative bleeding, postoperative liver function recovery, Clavien grade of complication severity and 5-year recurrence rate between the two groups (<jats:italic>P<\/jats:italic> &amp;lt; 0.05). There was no significant difference in postoperative quality of life between the two groups (<jats:italic>P<\/jats:italic> &amp;gt; 0.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>For patients with advanced hepatic alveolar echinococcosis whose objective cannot be achieved by conventional hepatectomy, quasi-radical resection of the lesion can not only reduce the risk and difficulty of surgery, but also the quality of life of the patients may be as good as that of radical resection.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fsurg.2021.821373","type":"journal-article","created":{"date-parts":[[2022,1,21]],"date-time":"2022-01-21T06:19:53Z","timestamp":1642745993000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Study on the Effect of Quasi-Radical Lesion Resection on the Quality of Life of Patients With Advanced Hepatic Alveolar Echinococcosis"],"prefix":"10.3389","volume":"8","author":[{"given":"Jide","family":"A","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinping","family":"Chai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenlu","family":"Guo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shunyun","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiangren","family":"A","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinyu","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2022,1,21]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1016\/bs.apar.2016.11.001","article-title":"Global distribution of alveolar and cystic echinococcosis","volume":"95","author":"Deplazes","year":"2017","journal-title":"Adv Parasitol."},{"key":"B2","doi-asserted-by":"publisher","first-page":"S1499","DOI":"10.1016\/j.hbpd.2021.03.010","article-title":"Monosegmental ALPPS combined with ante-situm liver resection: a novel strategy for end-stage hepatic alveolar echinococcosis","volume":"5","author":"Tang","year":"2021","journal-title":"Hepatobiliary Pancreat Dis Int."},{"key":"B3","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1080\/00015458.2018.1427838","article-title":"Hepatic alveolar echinococcosis","volume":"118","author":"Detry","year":"2018","journal-title":"Acta Chir Belg."},{"key":"B4","doi-asserted-by":"publisher","first-page":"1408","DOI":"10.1017\/S0031182020001390","article-title":"Comment on surgical approaches for definitive treatment of hepatic alveolar echinococcosis: results of a survey in 178 patients","volume":"147","author":"Akbulut","year":"2020","journal-title":"Parasitology."},{"key":"B5","doi-asserted-by":"publisher","first-page":"705","DOI":"10.16250\/j.32.1374.2018169","article-title":"Surgical treatment strategy for complex hepatic echinococcosis: a review","volume":"30","author":"Yamin","year":"2018","journal-title":"Chinese J Schistosomiasis Control."},{"key":"B6","doi-asserted-by":"publisher","first-page":"321","DOI":"10.3760\/cma.j.issn.1007-8118.2015.05.010","article-title":"Surgery combined with albendazole liposomes for advanced hepatic alveolar echinococcosis","volume":"21","author":"Shunyun","year":"2015","journal-title":"Chin J Hepatobiliary Surgery."},{"key":"B7","first-page":"38","article-title":"Da steckt der (Band-)Wurm drin! 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