{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T16:34:07Z","timestamp":1753893247601,"version":"3.41.2"},"reference-count":25,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,11,2]],"date-time":"2022-11-02T00:00:00Z","timestamp":1667347200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003995","name":"Natural Science Foundation of Anhui Province","doi-asserted-by":"publisher","award":["2008085QH422"],"award-info":[{"award-number":["2008085QH422"]}],"id":[{"id":"10.13039\/501100003995","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014984","name":"Wuhu City Science and Technology Bureau science and technology","doi-asserted-by":"publisher","award":["2021cg26;2021cg37"],"award-info":[{"award-number":["2021cg26;2021cg37"]}],"id":[{"id":"10.13039\/501100014984","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010816","name":"Anhui Provincial Science and Technology Department Key Research and Development Program Project","doi-asserted-by":"publisher","award":["201904a07020033"],"award-info":[{"award-number":["201904a07020033"]}],"id":[{"id":"10.13039\/501100010816","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Surg."],"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To describe the surgical techniques and short-term outcomes for 50 cases of modified sacrospinous ligament fixation <jats:italic>via<\/jats:italic> the anterior vaginal wall path for pelvic organ prolapse<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>100 patients with pelvic organ prolapse (stage III or stage IV based on POP-Q staging) from January 2018 to January 2020 were retrospectively analyzed. Among them, 50 patients received modified sacrospinous ligament fixation <jats:italic>via<\/jats:italic> the anterior vaginal wall path for pelvic organ prolapse (mSSLF group), while the other 50 patients received pelvic reconstruction using T4 mesh (T4 group). Operative time, blood loss, postoperative POP-Q score, length of the hospital stay, complications, and postoperative pain were compared between the two groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The duration of the operation in mSSLF group was (50\u2009\u00b1\u200915.2\u2005min), which was shorter than that of the T4 group (60\u2009\u00b1\u200914.8\u2005min) (<jats:italic>p\u2009<\/jats:italic>=\u20090.02). No intraoperative complications were reported from the mSSLF group, whereas one vascular injury occurred in the T4 group. In both groups, postoperative pain and painful intercourse was significantly lower in the mSSLF group than in the SSLF group (<jats:italic>p<\/jats:italic>\u2009&amp;lt;\u20090.001). The exposed mesh rate was lower than T4 group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The rates of intraoperative complications, postoperative pain and mesh erosion were significantly lower than those of the T4 group, but there was no significant difference in the efficacy and safety of the treatment of pelvic organ prolapse. So mSSLF may be a feasible technique to manage severe prolapse, with promising short-term efficacy and safety.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fsurg.2022.1010027","type":"journal-article","created":{"date-parts":[[2022,11,2]],"date-time":"2022-11-02T06:46:46Z","timestamp":1667371606000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Evaluation of the clinical effectiveness of modified sacrospinous ligament fixation via the anterior vaginal wall path for pelvic organ prolapse: A feasibility report based on 50 patients"],"prefix":"10.3389","volume":"9","author":[{"given":"Yuanyuan","family":"Lyu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huafeng","family":"Ding","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suhua","family":"Shi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin","family":"Ding","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chengcheng","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoming","family":"Guan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guantai","family":"Ni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yonghong","family":"Luo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2022,11,2]]},"reference":[{"key":"B1","first-page":"397","article-title":"Female pelvic medicine & reconstructive surgery","volume":"25","year":"2019"},{"key":"B2","first-page":"179","article-title":"Pelvic organ prolapse","volume":"96","author":"Iglesia","year":"2017","journal-title":"Am Fam Physician"},{"key":"B3","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1016\/j.gtc.2021.10.011","article-title":"Pelvic organ prolapse","volume":"51","author":"Collins","year":"2022","journal-title":"Gastroenterol Clin North Am"},{"key":"B4","doi-asserted-by":"publisher","first-page":"1554","DOI":"10.1001\/jama.2018.2827","article-title":"Effect of uterosacral ligament suspension vs sacrospinous ligament fixation with or without perioperative behavioral therapy for pelvic organ vaginal prolapse on surgical outcomes and prolapse symptoms at 5 years in the OPTIMAL randomized clinical trial","volume":"319","author":"Jelovsek","year":"2018","journal-title":"JAMA"},{"key":"B5","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1007\/s00192-010-1232-z","article-title":"Laparoscopic sacrospinous ligament fixation for uterovaginal prolapse: experience with 93 cases","volume":"22","author":"Wang","year":"2011","journal-title":"Int Urogynecol J"},{"key":"B6","doi-asserted-by":"publisher","first-page":"1","DOI":"10.4293\/JSLS.2017.00105","article-title":"A posterior approach to laparoscopic sacrospinous ligament suspension","volume":"22","author":"Kong","year":"2018","journal-title":"JSLS"},{"key":"B7","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1111\/j.1600-0412.1990.tb08027.x","article-title":"An integral theory of female urinary incontinence. Experimental and clinical considerations","volume":"153","author":"Petros","year":"1990","journal-title":"Acta Obstet Gynecol Scand Suppl"},{"key":"B8","doi-asserted-by":"publisher","first-page":"1717","DOI":"10.1016\/0002-9378(92)91562-O","article-title":"Anatomic aspects of vaginal eversion after hysterectomy","volume":"166","author":"DeLancey","year":"1992","journal-title":"Am J Obstet Gynecol"},{"key":"B9","doi-asserted-by":"publisher","first-page":"143","DOI":"10.4103\/GMIT.GMIT_7_19","article-title":"Current treatments for female pelvic floor dysfunctions","volume":"8","author":"Hong","year":"2019","journal-title":"Gynecol Minim Invasive Ther"},{"key":"B10","first-page":"102","article-title":"[Clinical efficacy and safety of transvaginal pelvic floor reconstruction with TiLOOP mesh]","volume":"56","author":"Huang","year":"2021","journal-title":"Zhonghua Fu Chan Ke Za Zhi"},{"key":"B11","first-page":"1010","article-title":"Laparoscopic suture hysteropexy for uterine prolapse","volume":"97","author":"Maher","year":"2001","journal-title":"Obstet Gynecol"},{"key":"B12","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1590\/s1677-5538.ibju.2018.0581","article-title":"Narrative review of the epidemiology, diagnosis and pathophysiology of pelvic organ prolapse","volume":"46","author":"Weintraub","year":"2020","journal-title":"Int Braz J Urol"},{"key":"B13","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1111\/luts.12303","article-title":"Quality of life and sexuality after bilateral sacrospinous fixation with vaginal hysterectomy for treatment of primary pelvic organ prolapse","volume":"12","author":"Yalcin","year":"2020","journal-title":"Low Urin Tract Symptoms"},{"key":"B14","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s00192-022-05092-x","article-title":"Anterior bilateral sacrospinous ligament fixation with concomitant anterior native tissue repair: a pilot study","author":"Delacroix","year":"2022","journal-title":"Int Urogynecol J"},{"key":"B15","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1002\/elsc.202000003","article-title":"Tissue engineering in female pelvic floor reconstruction","volume":"20","author":"Wu","year":"2020","journal-title":"Eng Life Sci"},{"key":"B16","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1111\/luts.12408","article-title":"Comparison of Prolift, Perigee-Apogee, Prosima, and Elevate transvaginal mesh systems in pelvic organ prolapse surgery: clinical outcomes of a long-term observational study","volume":"14","author":"Huang","year":"2022","journal-title":"Low Urin Tract Symptoms"},{"key":"B17","doi-asserted-by":"publisher","first-page":"100281","DOI":"10.1016\/j.esxm.2020.10.009","article-title":"Retrospective analysis of sexual function after transvaginal mesh surgery","volume":"9","author":"Khandwala","year":"2021","journal-title":"Sex Med"},{"key":"B18","first-page":"1908","article-title":"[Long-term mesh-related complications after total pelvic reconstruction surgery with tension-free transvaginal mesh]","volume":"101","author":"Liang","year":"2021","journal-title":"Zhonghua Yi Xue Za Zhi"},{"key":"B19","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1016\/j.tjog.2021.01.031","article-title":"The efficacy and complications of using transvaginal mesh to treat pelvic organ prolapse in Taiwan: a 10-year review","volume":"60","author":"Sun","year":"2021","journal-title":"Taiwan J Obstet Gynecol"},{"key":"B20","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1016\/j.tjog.2019.11.006","article-title":"Mesh-related complications in single-incision transvaginal mesh (TVM) and laparoscopic abdominal sacrocolpopexy (LASC)","volume":"59","author":"Li","year":"2020","journal-title":"Taiwan J Obstet Gynecol"},{"key":"B21","doi-asserted-by":"publisher","first-page":"314","DOI":"10.1097\/GRF.0000000000000615","article-title":"Urinary incontinence and pelvic organ prolapse","volume":"64","author":"Wong","year":"2021","journal-title":"Clin Obstet Gynecol"},{"key":"B22","first-page":"Cd013108","article-title":"Surgery for women with pelvic organ prolapse with or without stress urinary incontinence","volume":"8","author":"Baessler","year":"2018","journal-title":"Cochrane Database Syst Rev"},{"key":"B23","doi-asserted-by":"publisher","first-page":"688","DOI":"10.1002\/nau.24608","article-title":"External validation of a model predicting de novo stress urinary incontinence after pelvic organ prolapse surgery","volume":"40","author":"Yasa","year":"2021","journal-title":"Neurourol Urodyn"},{"key":"B24","doi-asserted-by":"publisher","first-page":"22011","DOI":"10.1038\/s41598-021-01565-z","article-title":"Inverse correlation between urethral length and continence before and after native tissue pelvic floor reconstruction","volume":"11","author":"Mothes","year":"2021","journal-title":"Sci Rep"},{"key":"B25","doi-asserted-by":"publisher","first-page":"1944","DOI":"10.1038\/s41598-020-58594-3","article-title":"Urodynamics mixed type urinary incontinence with advanced pelvic organ prolapse, management and outcomes","volume":"10","author":"Lo","year":"2020","journal-title":"Sci Rep"}],"container-title":["Frontiers in Surgery"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fsurg.2022.1010027\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,2]],"date-time":"2022-11-02T06:46:51Z","timestamp":1667371611000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fsurg.2022.1010027\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11,2]]},"references-count":25,"alternative-id":["10.3389\/fsurg.2022.1010027"],"URL":"https:\/\/doi.org\/10.3389\/fsurg.2022.1010027","relation":{},"ISSN":["2296-875X"],"issn-type":[{"type":"electronic","value":"2296-875X"}],"subject":[],"published":{"date-parts":[[2022,11,2]]},"article-number":"1010027"}}