{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T07:40:12Z","timestamp":1775634012612,"version":"3.50.1"},"reference-count":11,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,1,6]],"date-time":"2023-01-06T00:00:00Z","timestamp":1672963200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Surg."],"abstract":"<jats:p>Situs inversus totalis is a rare congenital anatomical anomaly that causes some difficult problems for surgeons when performing an operation. However, without histopathology specimens from surgery, a misdiagnosis of cancer may be unavoidable, in addition to affecting the improvement of prognosis. This study reports a rare patient with situs inversus totalis who presented with the main complaints of pruritus and vague abdominal pain. She was first misdiagnosed with cholangiocarcinoma and was finally diagnosed with duodenal papilla adenocarcinoma <jats:italic>via<\/jats:italic> laparoscopic pancreaticoduodenectomy. Situs inversus totalis was not a contraindication for surgery. Skilled surgeons and complete preparation during the perioperative period are two important keys to successful surgeries. Performing laparoscopic pancreaticoduodenectomy for patients with situs inversus totalis to avoid misdiagnosis of cancer and tailor appropriate therapy plans is cost-effective.<\/jats:p>","DOI":"10.3389\/fsurg.2022.1058580","type":"journal-article","created":{"date-parts":[[2023,1,6]],"date-time":"2023-01-06T06:02:25Z","timestamp":1672984945000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Avoiding misdiagnosis of duodenal papilla adenocarcinoma in a situs inversus totalis patient via laparoscopic pancreaticoduodenectomy: A rare case report"],"prefix":"10.3389","volume":"9","author":[{"given":"Hao","family":"Liang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ya-kun","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wu","family":"Pang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ming-liang","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2023,1,6]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"724","DOI":"10.1001\/archsurg.1949.01240030734014","article-title":"Situs inversus totalis; a statistical review of data on 76 cases with special reference to disease of the biliary tract","volume":"58","author":"Mayo","year":"1949","journal-title":"Arch Surg"},{"key":"B2","doi-asserted-by":"publisher","first-page":"W30","DOI":"10.1308\/147870810\/12699662980277","article-title":"Laparoscopic cholecystectomy in situs inversus totalis: is it safe?","volume":"92","author":"Hall","year":"2010","journal-title":"Ann R Coll Surg Engl"},{"key":"B3","doi-asserted-by":"publisher","first-page":"e0205","DOI":"10.1097\/md.0000000000010205","article-title":"Situs inversus totalis with solid pseudopapillary pancreatic tumor: a case report and review of literature","volume":"97","author":"Xiang","year":"2018","journal-title":"Medicine"},{"key":"B4","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1186\/s12876-022-02377-9","article-title":"Situs inversus totalis with local metastasis of gallbladder carcinoma and variation of the common hepatic artery","volume":"22","author":"Zhang","year":"2022","journal-title":"BMC Gastroenterol"},{"key":"B5","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1007\/s12328-021-01574-5","article-title":"Cholangitis secondary to obstructive choledocholithiases in an elderly woman with heterotaxy syndrome with polysplenia: report of a case and brief review of the literature","volume":"15","author":"L\u00e1inez Ramos-Bossini","year":"2022","journal-title":"Clin J Gastroenterol"},{"key":"B6","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1002\/ajmg.c.30228","article-title":"Disorders of left-right asymmetry: heterotaxy and situs inversus","author":"Sutherland","year":"2009","journal-title":"Am J Med Genet C Semin Med Genet"},{"key":"B7","doi-asserted-by":"publisher","first-page":"e29","DOI":"10.1097\/sle.0000000000000659","article-title":"The first report of laparoscopic pancreaticoduodenectomy for primary duodenal carcinoma in a patient with situs inversus totalis: report of a rare case","volume":"29","author":"Guo","year":"2019","journal-title":"Surg Laparosc Endosc Percutan Tech"},{"key":"B8","doi-asserted-by":"publisher","first-page":"1348","DOI":"10.1200\/jco.2012.46.8868","article-title":"Histomolecular phenotypes and outcome in adenocarcinoma of the ampulla of vater","volume":"31","author":"Chang","year":"2013","journal-title":"J Clin Oncol"},{"key":"B9","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1016\/j.ijscr.2020.02.009","article-title":"A report of two infant cases operated for jejunal duplication cyst associated with malrotation and volvulus","volume":"67","author":"Azzam","year":"2020","journal-title":"Int J Surg Case Rep"},{"key":"B10","doi-asserted-by":"publisher","first-page":"173","DOI":"10.20517\/ais.2022.26","article-title":"Artificial intelligence HPB surgery - current problems, future solutions?","volume":"2","author":"O\u2019Reilly","year":"2022","journal-title":"Artif Intell Surg"},{"key":"B11","doi-asserted-by":"publisher","first-page":"144","DOI":"10.20517\/ais.2022.11","article-title":"The challenges of deep learning in artificial intelligence and autonomous actions in surgery: a literature review","volume":"2","author":"Taher","year":"2022","journal-title":"Artif Intell Surg"}],"container-title":["Frontiers in Surgery"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fsurg.2022.1058580\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,6]],"date-time":"2023-01-06T06:02:28Z","timestamp":1672984948000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fsurg.2022.1058580\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,6]]},"references-count":11,"alternative-id":["10.3389\/fsurg.2022.1058580"],"URL":"https:\/\/doi.org\/10.3389\/fsurg.2022.1058580","relation":{},"ISSN":["2296-875X"],"issn-type":[{"value":"2296-875X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1,6]]},"article-number":"1058580"}}