{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T16:34:40Z","timestamp":1753893280485,"version":"3.41.2"},"reference-count":31,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,1,6]],"date-time":"2023-01-06T00:00:00Z","timestamp":1672963200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82072421"],"award-info":[{"award-number":["82072421"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Surg."],"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>The study aims to compare the implementation and prognosis of emergency digit replantation surgery before and after normalized corona virus disease 2019 (COVID-19) nucleic acid testing for patients taking emergency operation and to explore the influence of normalized COVID-19 nucleic acid testing on replantation surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Normalized COVID-19 nucleic acid testing for patients taking emergency operation has been carried out since 1 August 2021 at our hospital, which means each patient who needs emergency surgical treatment has to obtain either positive or negative results of COVID-19 nucleic acid before entering the operating room. This research reviewed and compared the prognosis of the injured extremity that had emergency severed digit replantation between June and September 2021, at the Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, and analyzed the impact of normalized COVID-19 nucleic acid testing on the outcome of the replanted fingers of different severity using disability of arm-shoulder-hand (DASH) and hand injury severity scoring (HISS) scoring systems.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 54 cases with 74 severed replanted phalanges were included replanted by the research group between 1 August and 30 September 2021, without any COVID-19 suspected\/confirmed case detected. Compared with previous period (1 June to 31 July, 2021), although the interval between emergency visits and emergency replantation did increase significantly after normalized COVID-19 nucleic acid testing [(3.83\u2009\u00b1\u20090.94) to (1.77\u2009\u00b1\u20090.67)\u2005h, <jats:italic>P\u2009<\/jats:italic>&amp;lt;\u20090.05], we observed no significant difference in the improvement rate of the DASH scoring of the disabled upper extremity 3-month postoperatively (<jats:italic>P\u2009<\/jats:italic>=\u20090.538) nor in the complication rate (<jats:italic>P\u2009<\/jats:italic>=\u20090.344). Moreover, there was no significant difference in the improvement rate of the DASH scoring of the disabled upper extremity 3-month postoperatively in patients with different traumatic severities before and after normalized COVID-19 nucleic acid testing (moderate <jats:italic>P<\/jats:italic>\u2009=\u20090.269, severe <jats:italic>P<\/jats:italic>\u2009=\u20090.055, major <jats:italic>P<\/jats:italic>\u2009=\u20090.149).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Despite the preoperative delay, the policy of COVID-19 nucleic acid testing normalization does not have explicit influence on the short-term outcomes of emergency digit replantation surgery. With this evidence, microsurgeons could pay attention to the patients' anxiety and spend more effort in comforting them during the prolonged preoperative wait. These insights may have implications for other emergency department resource management whenever a social crisis occurs.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fsurg.2022.1078933","type":"journal-article","created":{"date-parts":[[2023,1,6]],"date-time":"2023-01-06T10:42:25Z","timestamp":1673001745000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Influence on emergency digit replantation and outcome assessment after COVID-19 virus nucleic acid testing normalization"],"prefix":"10.3389","volume":"9","author":[{"given":"Kunqi","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rui","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shanyu","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shenghe","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feiyan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jia","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qinglin","family":"Kang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2023,1,6]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1007\/s11077-020-09381-4","article-title":"COVID-19 and the policy sciences: initial reactions and perspectives","author":"Weible","year":"2020","journal-title":"Policy Sci"},{"key":"B2","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1186\/s12961-021-00770-6","article-title":"Coevolution of COVID-19 research and China\u2019s policies","volume":"19","author":"Cheng","year":"2021","journal-title":"Health Res Policy Syst"},{"key":"B3","doi-asserted-by":"publisher","first-page":"755508","DOI":"10.3389\/fcimb.2021.755508","article-title":"Quality management for point-of-care testing of pathogen nucleic acids: Chinese expert consensus","volume":"11","author":"Mo","year":"2021","journal-title":"Front Cell Infect Microbiol"},{"key":"B4","doi-asserted-by":"publisher","first-page":"15589447211028918","DOI":"10.1177\/15589447211028918","article-title":"The impact of COVID-19 on hand trauma","author":"Saleh","year":"2021","journal-title":"Hand (N Y)"},{"key":"B5","doi-asserted-by":"publisher","first-page":"e0263435","DOI":"10.1371\/journal.pone.0263435","article-title":"Emergency department visits due to hand trauma and subsequent emergency hand surgery in three Finnish hospitals during the first and second waves of COVID-19 pandemic","volume":"17","author":"Kuitunen","year":"2022","journal-title":"PLoS One"},{"key":"B6","doi-asserted-by":"publisher","first-page":"675","DOI":"10.1016\/j.hansur.2021.05.011","article-title":"Hand surgery during the COVID-19 pandemic: clinical care best practices","volume":"40","author":"Bartoletta","year":"2021","journal-title":"Hand Surg Rehabil"},{"key":"B7","doi-asserted-by":"publisher","first-page":"1497","DOI":"10.1007\/s00264-020-04654-2","article-title":"Impact of the CoronaVirus disease 2019 lockdown on hand and upper limb emergencies: experience of a referred university trauma hand centre in Paris, France","volume":"44","author":"Pichard","year":"2020","journal-title":"Int Orthop"},{"key":"B8","doi-asserted-by":"publisher","first-page":"1357","DOI":"10.1016\/j.bjps.2020.05.026","article-title":"Managing hand trauma during the COVID-19 pandemic using a one-stop clinic","volume":"73","author":"Sadr","year":"2020","journal-title":"J Plast Reconstr Aesthet Surg"},{"key":"B9","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1007\/s11552-013-9520-y","article-title":"Replantation and revascularization vs. amputation in injured digits","volume":"8","author":"Mulders","year":"2013","journal-title":"Hand (N Y)"},{"key":"B10","doi-asserted-by":"publisher","first-page":"679","DOI":"10.1016\/j.injury.2021.02.024","article-title":"Epidemiology of hand traumas during the COVID-19 confinement period","volume":"52","author":"Fortane","year":"2021","journal-title":"Injury"},{"key":"B11","doi-asserted-by":"publisher","first-page":"883","DOI":"10.1016\/j.jhsa.2015.01.006","article-title":"Delayed and suspended replantation for complete amputation of digits and hands","volume":"40","author":"Woo","year":"2015","journal-title":"J Hand Surg Am"},{"key":"B12","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1055\/s-0038-1626689","article-title":"Predictors of digit survival following replantation: quantitative review and meta-analysis","volume":"10","author":"Shaterian","year":"2018","journal-title":"J Hand Microsurg"},{"year":"","key":"B13"},{"key":"B14","doi-asserted-by":"publisher","first-page":"105","DOI":"10.3760\/cma.j.cn441206-20200402-00187","article-title":"Chinese Microsurgery Society of Chinese Medical Association. Experts consensus on performing microsurgery during the epidemic of COVID-19","volume":"43","author":"Shaterian","year":"2020","journal-title":"Chin J Microsurg"},{"key":"B15","doi-asserted-by":"publisher","first-page":"743","DOI":"10.1097\/PRS.0000000000003665","article-title":"Antithrombotic therapies in digit replantation with papaverine administration: a prospective, observational study","volume":"140","author":"Zhu","year":"2017","journal-title":"Plast Reconstr Surg"},{"key":"B16","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1016\/S0266-7681(05)80187-1","article-title":"The hand injury severity scoring system","volume":"21","author":"Campbell","year":"1996","journal-title":"J Hand Surg Br"},{"key":"B17","doi-asserted-by":"publisher","first-page":"602","DOI":"10.1002\/(SICI)1097-0274(199606)29:6%3C602::AID-AJIM4%3E3.0.CO;2-L","article-title":"Development of an upper extremity outcome measure: the DASH (disabilities of the arm, shoulder and hand) [corrected]. The upper extremity collaborative group (UECG)","volume":"29","author":"Hudak","year":"1996","journal-title":"Am J Ind Med"},{"key":"B18","doi-asserted-by":"publisher","first-page":"838","DOI":"10.1016\/S0140-6736(11)60815-5","article-title":"Changing the future of obesity: science, policy, and action","volume":"378","author":"Gortmaker","year":"2011","journal-title":"Lancet"},{"key":"B19","doi-asserted-by":"publisher","first-page":"113423","DOI":"10.1016\/j.socscimed.2020.113423","article-title":"Understanding the policy dynamics of COVID-19 in the UK: early findings from interviews with policy makers and health care professionals","volume":"266","author":"Atkinson","year":"2020","journal-title":"Soc Sci Med"},{"key":"B20","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1177\/1457496920982763","article-title":": who, how, why, when, what, and where to diagnose and operate?","volume":"110","author":"Podda","year":"2021","journal-title":"Scand J Surg"},{"key":"B21","doi-asserted-by":"publisher","first-page":"3768","DOI":"10.3760\/cma.j.cn112137-20200814-02385","article-title":"Management protocol and outcome assessment of ruptured intracranial aneurysm emergency surgery during coronavirus disease 2019 pandemic","volume":"100","author":"Ma","year":"2020","journal-title":"Zhonghua Yi Xue Za Zhi"},{"key":"B22","doi-asserted-by":"publisher","first-page":"756","DOI":"10.1007\/s12630-020-01617-4","article-title":"What we do when a COVID-19 patient needs an operation: operating room preparation and guidance","volume":"67","author":"Ti","year":"2020","journal-title":"Can J Anaesth"},{"key":"B23","doi-asserted-by":"publisher","first-page":"3116","DOI":"10.3390\/jcm11113116","article-title":"When to achieve complete revascularization in infarct-related cardiogenic shock","volume":"11","author":"Masiero","year":"2022","journal-title":"J Clin Med"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1007\/s43678-022-00301-4","article-title":"About time! A scoping review of public-facing emergency department wait time displays in Canada","author":"Rathagirishnan","year":"2022","journal-title":"CJEM"},{"key":"B25","doi-asserted-by":"publisher","first-page":"1261","DOI":"10.1016\/j.bjps.2022.01.016","article-title":"Finger replantation as an office hour procedure: is overnight delay safe?","volume":"75","author":"Golash","year":"2022","journal-title":"J Plast Reconstr Aesthet Surg"},{"key":"B26","doi-asserted-by":"publisher","first-page":"561","DOI":"10.3760\/cma.j.cn115530-20200426-00286","article-title":"Treatment of patients with orthopaedic trauma during COVID-19 epidemic","volume":"22","author":"Chang","year":"2020","journal-title":"Chin J Orthop Trauma"},{"key":"B27","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1055\/s-0031-1284232","article-title":"Anxiety and trauma\u00a0perception and quality of life in patients who have undergone replantation","volume":"27","author":"Gokce","year":"2011","journal-title":"J Reconstr Microsurg"},{"key":"B28","doi-asserted-by":"publisher","first-page":"320","DOI":"10.1016\/j.atherosclerosis.2005.06.001","article-title":"Anxiety in relation to inflammation and coagulation markers, among healthy adults: the ATTICA study","volume":"185","author":"Pitsavos","year":"2006","journal-title":"Atherosclerosis"},{"key":"B29","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1016\/j.ijsu.2019.07.027","article-title":"Pre-injury level of anxiety is associated with the rate of digit replant failure: a prospective cohort study","volume":"69","author":"Jin","year":"2019","journal-title":"Int J Surg"},{"key":"B30","doi-asserted-by":"publisher","first-page":"753","DOI":"10.1177\/1753193415624663","article-title":"Replantation of digits: a review of predictive factors for survival","volume":"41","author":"Breahna","year":"2016","journal-title":"J Hand Surg Eur Vol"},{"key":"B31","doi-asserted-by":"publisher","first-page":"e2128765","DOI":"10.1001\/jamanetworkopen.2021.28765","article-title":"Variation in surgeon\u00a0proficiency scores and association with digit replantation outcomes","volume":"4","author":"Yoon","year":"2021","journal-title":"JAMA Netw Open"}],"container-title":["Frontiers in Surgery"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fsurg.2022.1078933\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,6]],"date-time":"2023-01-06T10:42:31Z","timestamp":1673001751000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fsurg.2022.1078933\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,6]]},"references-count":31,"alternative-id":["10.3389\/fsurg.2022.1078933"],"URL":"https:\/\/doi.org\/10.3389\/fsurg.2022.1078933","relation":{},"ISSN":["2296-875X"],"issn-type":[{"type":"electronic","value":"2296-875X"}],"subject":[],"published":{"date-parts":[[2023,1,6]]},"article-number":"1078933"}}