{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T16:34:51Z","timestamp":1753893291967,"version":"3.41.2"},"reference-count":9,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,2,2]],"date-time":"2022-02-02T00:00:00Z","timestamp":1643760000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Surg."],"abstract":"<jats:p>Thymic cysts are rare lesions (1\u20135% of all mediastinal masses) and, most of the times, are incidental findings. The coexistence of a lymphoma and a thymic cyst is rare. In the case reported herein, microscopic foci of a diffuse large B-cell lymphoma were identified in the wall of a resected thymic cyst. This case report adds to the current knowledge of this rare entity and highlights the necessity of early surgical resection of mediastinal cysts over watchful waiting.<\/jats:p>","DOI":"10.3389\/fsurg.2022.788047","type":"journal-article","created":{"date-parts":[[2022,2,2]],"date-time":"2022-02-02T04:57:36Z","timestamp":1643777856000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Case Report: Diffuse Large B-Cell Lymphoma in the Wall of a Thymic Cyst"],"prefix":"10.3389","volume":"9","author":[{"given":"Apostolos C.","family":"Agrafiotis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ioannis","family":"Paralikas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kanellos","family":"Giakoumakis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sotirios D.","family":"Moraitis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2022,2,2]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1378\/chest.124.1.125","article-title":"Clinical spectrum of mediastinal cysts","volume":"124","author":"Takeda","year":"2003","journal-title":"Chest"},{"key":"B2","doi-asserted-by":"publisher","first-page":"388","DOI":"10.1097\/00000478-199104000-00008","article-title":"Multilocular thymic cyst: an acquired reactive process. study of 18 cases","volume":"15","author":"Suster","year":"1991","journal-title":"Am J Surg Pathol"},{"key":"B3","doi-asserted-by":"publisher","first-page":"365","DOI":"10.5761\/atcs.oa.13-00151","article-title":"Single institutional experience with primary mediastinal cysts: clinicopathological study of 108 resected cases","volume":"20","author":"Kozu","year":"2014","journal-title":"Ann Thorac Cardiovasc Surg"},{"key":"B4","doi-asserted-by":"publisher","first-page":"345","DOI":"10.5144\/0256-4947.1994.345","article-title":"Thymic lymphoma with thymic cyst","volume":"14","author":"Ul Haque","year":"1994","journal-title":"Ann Saudi Med."},{"key":"B5","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1097\/JTO.0000000000000295","article-title":"Approaching the patient with an anterior mediastinal mass: a guide for radiologists","volume":"9","author":"Carter","year":"2014","journal-title":"J Thorac Oncol"},{"key":"B6","doi-asserted-by":"publisher","first-page":"795037","DOI":"10.1155\/2010\/795037","article-title":"Hodgkin lymphoma in a thymic cyst: report of a case with multiple secondary neoplasms","volume":"2010","author":"Almarzooqi","year":"2010","journal-title":"Case Rep Med."},{"key":"B7","doi-asserted-by":"publisher","first-page":"e561","DOI":"10.1016\/j.athoracsur.2016.04.101","article-title":"Slow-growing mediastinal grey zone lymphoma originating from a formerly resected multilocular thymic cyst","volume":"102","author":"Tabata","year":"2016","journal-title":"Ann Thorac Surg."},{"key":"B8","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1136\/thx.38.5.392","article-title":"Hodgkin's disease in a large thymic cyst in a child","volume":"38","author":"Smith","year":"1983","journal-title":"Thorax."},{"key":"B9","doi-asserted-by":"publisher","first-page":"633","DOI":"10.1136\/thx.42.8.633","article-title":"Benign thymic cysts in Hodgkin's disease: report of a case and review of published cases","volume":"42","author":"Lewis","year":"1987","journal-title":"Thorax."}],"container-title":["Frontiers in Surgery"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fsurg.2022.788047\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,2]],"date-time":"2022-02-02T04:57:38Z","timestamp":1643777858000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fsurg.2022.788047\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2,2]]},"references-count":9,"alternative-id":["10.3389\/fsurg.2022.788047"],"URL":"https:\/\/doi.org\/10.3389\/fsurg.2022.788047","relation":{},"ISSN":["2296-875X"],"issn-type":[{"type":"electronic","value":"2296-875X"}],"subject":[],"published":{"date-parts":[[2022,2,2]]},"article-number":"788047"}}