{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T22:23:08Z","timestamp":1772576588136,"version":"3.50.1"},"reference-count":19,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,2,17]],"date-time":"2022-02-17T00:00:00Z","timestamp":1645056000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Surg."],"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>It is not known whether appendectomy for acute appendicitis (AA) increases the Cesarean section (CS) rate and whether CS increases the likelihood of AA and appendectomy in the early puerperium. In this study, delivery type and delivery outcomes and appendectomy during pregnancy and puerperium were analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This cross-sectional retrospective study was performed on 11,513 women, delivered during 2015\u20132020. Inclusion criteria were patients undergoing appendectomy for AA during pregnancy and the first 6 weeks after delivery. Evaluating parameters were age, parity, gestational week at birth, delivery type, and babies' birth weight.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Thirty-two patients underwent appendectomy: 12 during pregnancy (2 in the first trimester, 6 in the second trimester, 4 in the third trimester) and 20 women during puerperium. 58.2% of pregnant women and 65% of puerperal women were submitted to CS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Half of the women who underwent appendectomy for AA during pregnancy may require urgent CS. The cause of acute abdomen in the postpartum period, especially in the first week, could be AA, especially in women delivered by CS.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fsurg.2022.819418","type":"journal-article","created":{"date-parts":[[2022,2,17]],"date-time":"2022-02-17T04:51:55Z","timestamp":1645073515000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":5,"title":["Are Cesarean Section and Appendectomy in Pregnancy and Puerperium Interrelated? A Cohort Study"],"prefix":"10.3389","volume":"9","author":[{"given":"Banuhan","family":"\u015eahin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Tinelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Goran","family":"Augustin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2022,2,17]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1016\/j.ejogrb.2006.07.052","article-title":"Non-obstetrical acute abdomen during pregnancy","volume":"131","author":"Augustin","year":"2007","journal-title":"Eur J Obstet Gynecol Reprod Biol."},{"key":"B2","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1016\/j.jviscsurg.2015.09.017","article-title":"Abdominal emergencies during pregnancy","volume":"152","author":"Bouyou","year":"2015","journal-title":"J Visc Surg."},{"key":"B3","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1016\/j.jviscsurg.2012.06.003","article-title":"Acute appendicitis in pregnancy: specific features of diagnosis and treatment","volume":"149","author":"Miloudi","year":"2012","journal-title":"J Visc Surg."},{"key":"B4","doi-asserted-by":"publisher","first-page":"332","DOI":"10.1097\/SLA.0000000000000780","article-title":"Risk of acute appendicitis in and around pregnancy: a population-based cohort study from England","volume":"261","author":"Zingone","year":"2015","journal-title":"Ann Surg."},{"key":"B5","doi-asserted-by":"publisher","first-page":"1025","DOI":"10.1177\/1933719116676395","article-title":"Regulatory T cells show dynamic behavior during late pregnancy, delivery, and the postpartum period","volume":"24","author":"Lima","year":"2017","journal-title":"Reprod Sci."},{"key":"B6","doi-asserted-by":"publisher","first-page":"1863","DOI":"10.1038\/s41598-018-38304-w","article-title":"Inflammatory and anti-inflammatory markers in plasma: from late pregnancy to early postpartum","volume":"9","author":"Br\u00e4nn","year":"2019","journal-title":"Sci Rep."},{"key":"B7","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1007\/s40477-018-0287-4","article-title":"Uncommon obstetric and gynecologic emergencies associated with pregnancy: ultrasound diagnosis","volume":"21","author":"Youssef","year":"2018","journal-title":"J Ultrasound."},{"key":"B8","doi-asserted-by":"publisher","first-page":"883","DOI":"10.2214\/AJR.05.0270","article-title":"Revisiting MRI for appendix location during pregnancy","volume":"186","author":"Oto","year":"2006","journal-title":"AJR Am J Roentgenol."},{"key":"B9","doi-asserted-by":"publisher","first-page":"805","DOI":"10.1097\/AOG.0b013e3181b6f6cc","article-title":"The appendix in pregnancy: confirming historical observations with a contemporary modality","volume":"114","author":"Pates","year":"2009","journal-title":"Obstet Gynecol."},{"key":"B10","doi-asserted-by":"publisher","first-page":"2601","DOI":"10.1007\/s00268-020-05524-z","article-title":"Major variation in the incidence of appendicitis before, during and after pregnancy: a population-based cohort study","volume":"44","author":"Moltubak","year":"2020","journal-title":"World J Surg."},{"key":"B11","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/j.ajog.2009.08.029","article-title":"Hospital readmission after delivery: evidence for an increased incidence of nonurogenital infection in the immediate postpartum period","volume":"202","author":"Belfort","year":"2010","journal-title":"Am J Obstet Gynecol."},{"key":"B12","doi-asserted-by":"publisher","first-page":"600","DOI":"10.1016\/S0368-2315(05)82885-6","article-title":"Appendicitis and pregnancy: 21 cases","volume":"34","author":"Lebeau","year":"2005","journal-title":"J Gynecol Obstet Biol Reprod (Paris)."},{"key":"B13","doi-asserted-by":"publisher","first-page":"10","DOI":"10.7860\/JCDR\/2015\/11970.6642","article-title":"Appendicitis in postpartum period: a diagnostic challenge","volume":"9","author":"Wadhawan","year":"2015","journal-title":"J Clin Diagn Res."},{"key":"B14","doi-asserted-by":"publisher","first-page":"467","DOI":"10.1016\/j.amjsurg.2005.03.033","article-title":"Pregnancy outcome following non-obstetric surgical intervention","volume":"190","author":"Cohen-Kerem","year":"2005","journal-title":"Am J Surg."},{"key":"B15","doi-asserted-by":"publisher","first-page":"661","DOI":"10.1007\/s00404-014-3276-7","article-title":"Evaluation of obstetrical and fetal outcomes in pregnancies complicated by acute appendicitis","volume":"290","author":"Abbasi","year":"2014","journal-title":"Arch Gynecol Obstet."},{"key":"B16","doi-asserted-by":"publisher","first-page":"1204","DOI":"10.1007\/s11605-012-1858-x","article-title":"Acute appendicitis and adverse pregnancy outcomes: a nationwide population-based study","volume":"16","author":"Wei","year":"2012","journal-title":"J Gastrointest Surg."},{"key":"B17","doi-asserted-by":"publisher","first-page":"4245","DOI":"10.1007\/s00464-020-07674-6","article-title":"Discordant outcomes of laparoscopic versus open appendectomy for suspected appendicitis during pregnancy in published meta-analyses: an overview of systematic reviews","volume":"34","author":"Augustin","year":"2020","journal-title":"Surg Endosc."},{"key":"B18","first-page":"513","article-title":"Acute periappendicitis after an elective section","volume":"114","author":"Borup","year":"1992","journal-title":"Zentralbl Gynakol."},{"key":"B19","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1159\/000317270","article-title":"Appendectomy in the gynecological setting: intraoperative findings and corresponding histopathology","volume":"71","author":"Shavell","year":"2011","journal-title":"Gynecol Obstet Invest."}],"container-title":["Frontiers in Surgery"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fsurg.2022.819418\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,17]],"date-time":"2022-02-17T04:51:58Z","timestamp":1645073518000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fsurg.2022.819418\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2,17]]},"references-count":19,"alternative-id":["10.3389\/fsurg.2022.819418"],"URL":"https:\/\/doi.org\/10.3389\/fsurg.2022.819418","relation":{},"ISSN":["2296-875X"],"issn-type":[{"value":"2296-875X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,2,17]]},"article-number":"819418"}}