{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T22:06:26Z","timestamp":1772661986200,"version":"3.50.1"},"reference-count":39,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,4,11]],"date-time":"2022-04-11T00:00:00Z","timestamp":1649635200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Surg."],"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Desmoid fibromatosis (DF) is a rare clonal proliferation of fibroblasts and myofibroblasts. It develops in the connective tissues and does not metastasize but may infiltrate adjacent structures. Because of the rarity of these tumors and the unpredictable natural history of the disease, well-defined and precise guidelines of the optimal treatment for DF have not been formulated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case Presentation<\/jats:title><jats:p>Here, we present a giant abdominal DF that invaded the right spermatic cord and iliac vessels. The lesion was excised with external iliac artery dissection; however, the vein was sacrificed. The abdominal wall defect was then repaired with a polypropylene mesh. The lesional cells are positive for \u03b2-catenin.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In the past decades, there has been a change in the treatment of DF. The \u201cwait and see\u201d policy has been considered initially in most cases. Surgical intervention remains a valid option for symptomatic lesions. The optimal regimes of the tumor should not take the risk of making the patient more symptomatic than the lesion itself.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fsurg.2022.851164","type":"journal-article","created":{"date-parts":[[2022,4,11]],"date-time":"2022-04-11T05:37:28Z","timestamp":1649655448000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":6,"title":["Surgical Management of a Giant Desmoid Fibromatosis of Abdominal Wall With Vessels Invasion in a Young Man: A Case Report and Review of the Literature"],"prefix":"10.3389","volume":"9","author":[{"given":"Jiming","family":"Zhao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fajuan","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhigang","family":"Yao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bin","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhihong","family":"Niu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"He","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2022,4,11]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"2399","DOI":"10.1093\/annonc\/mdx323","article-title":"An update on the management of sporadic desmoid-type fibromatosis: a European consensus initiative between sarcoma PAtients EuroNet (SPAEN) and European organization for research and treatment of cancer (EORTC)\/soft tissue and bone sarcoma group (STBSG)","volume":"28","author":"Kasper","year":"2017","journal-title":"Ann Oncol."},{"key":"B2","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1016\/j.ejca.2016.02.008","article-title":"Management of desmoid tumours: a nationwide survey of labelled reference centre networks in France","volume":"58","author":"Penel","year":"2016","journal-title":"Eur J Cancer."},{"key":"B3","doi-asserted-by":"publisher","first-page":"694","DOI":"10.1002\/bjs.9053","article-title":"Desmoid tumour biology in patients with familial adenomatous polyposis coli: desmoid tumour biology in familial adenomatous polyposis","volume":"100","author":"Schiessling","year":"2013","journal-title":"Br J Surg."},{"key":"B4","doi-asserted-by":"publisher","first-page":"462","DOI":"10.1016\/j.ejso.2007.06.006","article-title":"Extra-abdominal primary fibromatosis: aggressive management could be avoided in a subgroup of patients","volume":"34","author":"Bonvalot","year":"2008","journal-title":"Eur J Surg Oncol."},{"key":"B5","doi-asserted-by":"publisher","first-page":"1214","DOI":"10.1002\/bjs.9194","article-title":"Local recurrence after surgery for primary extra-abdominal desmoid-type fibromatosis: recurrence of desmoid-type fibromatosis","volume":"100","author":"van Broekhoven","year":"2013","journal-title":"Br J Surg."},{"key":"B6","doi-asserted-by":"publisher","first-page":"653","DOI":"10.1097\/01.pas.0000157938.95785.da","article-title":"Nuclear b-catenin expression distinguishes deep fibromatosis from other benign and malignant fibroblastic and myofibroblastic lesions","volume":"29","author":"Bhattacharya","year":"2005","journal-title":"Am J Surg Pathol."},{"key":"B7","doi-asserted-by":"publisher","first-page":"3553","DOI":"10.1200\/JCO.2010.33.5489","article-title":"Prognostic factors influencing progression-free survival determined from a series of sporadic desmoid tumors: a wait-and-see policy according to tumor presentation","volume":"29","author":"Salas","year":"2011","journal-title":"J Clin Oncol."},{"key":"B8","doi-asserted-by":"publisher","first-page":"1517","DOI":"10.1002\/(SICI)1097-0142(20000401)88:7<1517::AID-CNCR3>3.0.CO;2-9","article-title":"Surgery versus radiation therapy for patients with aggressive fibromatosis or desmoid tumors: a comparative review of 22 articles","volume":"88","author":"Nuyttens","year":"2000","journal-title":"Cancer."},{"key":"B9","volume-title":"WHO Classification of Tumor. 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