{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T15:29:05Z","timestamp":1784647745186,"version":"3.55.0"},"reference-count":34,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,4,6]],"date-time":"2022-04-06T00:00:00Z","timestamp":1649203200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Surg."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Colocolic intussusception is a rare subtype of intussusception mostly caused by juvenile polyps. The treatment of colocolic intussusception caused by other pathologic lead points in children remains poorly understood.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>A systematic literature review was performed between January 2000 and June 2021 to characterize the comprehensive treatment of colocolic intussusception in children. This report also included patients admitted to our center between January 2010 and June 2021 who were not previously reported in the literature.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We identified 27 patients in 20 studies in addition to 17 patients from our center for a total of 44 patients (median age, 4.4 years; 52.3% male). The lead point was identified in 40 patients (40\/44, 90.9%). The most common lead point was juvenile polyps (19\/44, 43.2%). A therapeutic enema was performed in 15 patients with colocolic intussusception caused by juvenile polyps and was successful in 9 patients (9\/15, 60.0%). Colonoscopic polypectomy was subsequently performed in 8 patients and was successful in 7 patients (7\/8, 87.5%). The other patient had undergone laparoscopic exploration, and no abnormality was found. Subsequently, the patient underwent open surgery. The patients with colocolic intussusception caused by other pathologic lead points almost underwent surgical treatment (15\/21, 71.4%), including 13 open surgeries and 2 laparoscopic surgeries.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>A therapeutic enema followed by colonoscopic polypectomy is feasible to treat colocolic intussusception caused by juvenile polyps unless the patient has bowel perforation; however, surgery is sometimes needed. For patients with colocolic intussusception caused by other pathologic lead points, open surgery remains the primary treatment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fsurg.2022.873624","type":"journal-article","created":{"date-parts":[[2022,4,6]],"date-time":"2022-04-06T00:24:05Z","timestamp":1649204645000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":15,"title":["Colocolic Intussusception in Children: A Case Series and Review of the Literature"],"prefix":"10.3389","volume":"9","author":[{"given":"Jiayu","family":"Yan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiulong","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunhui","family":"Peng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenbo","family":"Pang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yajun","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2022,4,6]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"495","DOI":"10.1016\/j.jpedsurg.2018.10.099","article-title":"et al. Operative treatment for intussusception: should an incidental appendectomy be performed?","volume":"54","author":"Wang","year":"2018","journal-title":"J Pediatr Surg."},{"key":"B2","doi-asserted-by":"publisher","first-page":"469","DOI":"10.1016\/j.surg.2007.07.015","article-title":"Current success in the treatment of intussusception in children","volume":"142","author":"Kaiser","year":"2007","journal-title":"Surgery."},{"key":"B3","doi-asserted-by":"publisher","first-page":"2150","DOI":"10.1016\/j.jpedsurg.2019.09.039","article-title":"Management of recurrent ileocolic intussusception","volume":"55","author":"Cho","year":"2020","journal-title":"J Pediatr Surg."},{"key":"B4","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1007\/s00383-002-0924-y","article-title":"Post-operative colocolic intussusception","volume":"19","author":"Emil","year":"2003","journal-title":"Pediatr Surg Int."},{"key":"B5","doi-asserted-by":"publisher","first-page":"e17","DOI":"10.1016\/j.jpedsurg.2008.10.037","article-title":"ganglioneuroma of the sigmoid colon presenting as leading point of intussusception in a child: a case report","volume":"44","author":"Soccorso","year":"2009","journal-title":"J Pediatr Surg."},{"key":"B6","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1007\/s10140-019-01727-7","article-title":"Colocolic intussusceptions in children: a pictorial essay and review of the literature","volume":"27","author":"Richer","year":"2020","journal-title":"Emerg Radiol."},{"key":"B7","doi-asserted-by":"publisher","first-page":"261","DOI":"10.4103\/0189-6725.137338","article-title":"child with colo-colonic intussusception due to a large colonic polyp: case report and literature review","volume":"11","author":"Takahashi","year":"2014","journal-title":"Afr J Paediatr Surg."},{"key":"B8","doi-asserted-by":"publisher","first-page":"6494075","DOI":"10.1155\/2018\/6494075","article-title":"Infantile hemangioma presenting as colocolic intussusception in an infant case report with review of pathologic lead points","volume":"24","author":"Rais","year":"2018","journal-title":"Case Rep Pediatr."},{"key":"B9","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1097\/PEC.0000000000000480","article-title":"Enterobius vermicularis as a cause of intestinal occlusion: how to avoid unnecessary surgery","volume":"32","author":"Adorisio","year":"2016","journal-title":"Pediatr Emerg Care."},{"key":"B10","doi-asserted-by":"publisher","first-page":"84","DOI":"10.4021\/jmc402w","article-title":"Pediatric colocolic intussusception with pathologic lead point: a case report","volume":"3","author":"Abrahams","year":"2012","journal-title":"J Med Cases."},{"key":"B11","doi-asserted-by":"publisher","first-page":"1144","DOI":"10.1016\/j.jpedsurg.2004.03.075","article-title":"Recurrent colocolic intussusception in a child with hereditary angioneurotic edema: reduction by air enema","volume":"39","author":"Pritzker","year":"2004","journal-title":"J Pediatr Surg."},{"key":"B12","doi-asserted-by":"publisher","first-page":"400","DOI":"10.1007\/s00383-004-1339-8","article-title":"Ileal invagination of the sigmoid colon producing a sigmoidorectal intussusception combined with rectal prolapse in a 3-year-old child","volume":"21","author":"Abantanga","year":"2005","journal-title":"Pediatr Surg Int."},{"key":"B13","doi-asserted-by":"publisher","first-page":"358","DOI":"10.1002\/ppul.20246","article-title":"Intussusceptions arising from two different sites in a child with cystic fibrosis","volume":"40","author":"Hafen","year":"2005","journal-title":"Pediatr Pulmonol."},{"key":"B14","doi-asserted-by":"publisher","first-page":"700","DOI":"10.1007\/s00247-008-0782-4","article-title":"Intussusception mimicking rectal prolapse","volume":"38","author":"Tennant","year":"2008","journal-title":"Pediatr Radiol."},{"key":"B15","first-page":"373","article-title":"Colocolic intussusception without lead point; a case report and literature review","volume":"18","author":"Rahim","year":"2008","journal-title":"Iran J Pediatr."},{"key":"B16","doi-asserted-by":"publisher","first-page":"e17","DOI":"10.1016\/j.jpedsurg.2009.09.011","article-title":"Colocolic intussusception in a preterm infant with intestinal malrotation","volume":"44","author":"Al-Jahdali","year":"2009","journal-title":"J Pediatr Surg."},{"key":"B17","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1007\/s12328-010-0141-5","article-title":"Intussusception in a child caused by capillary hemangioma of the colon","volume":"3","author":"Utsumi","year":"2010","journal-title":"Clin J Gastroenterol."},{"key":"B18","doi-asserted-by":"publisher","first-page":"e225","DOI":"10.1111\/j.1399-3046.2011.01569.x","article-title":"Colocolonic intussusception in a four-yr-old with a heart transplant: a case report and review of the literature","volume":"16","author":"Sanchez","year":"2012","journal-title":"Pediatr Transplant."},{"key":"B19","doi-asserted-by":"publisher","first-page":"106831","DOI":"10.1155\/2013\/106831","article-title":"Colocolic intussusception in an older child: a rare case report and a literature review","volume":"2013","author":"Das","year":"2013","journal-title":"Case Rep Surg."},{"key":"B20","first-page":"19","article-title":"Colonic gastrointestinal stromal tumour presenting as intussusception","volume":"4","author":"Ratan","year":"2013","journal-title":"APSP J Case Rep."},{"key":"B21","doi-asserted-by":"publisher","first-page":"233","DOI":"10.4103\/0971-9261.142017","article-title":"rare case of kaposiform hemangioendothelioma presenting as intussusception in a 4-month-old child without Kasabach-Merrit syndrome: a case report","volume":"19","author":"Kurian","year":"2014","journal-title":"J Indian Assoc Pediatr Surg."},{"key":"B22","doi-asserted-by":"publisher","first-page":"PD9","DOI":"10.7860\/JCDR\/2016\/22049.9068","article-title":"Colocolic intussusception in a child with pathologic lead point along with intestinal malrotation-a rare case report and brief review","volume":"10","author":"Tripathy","year":"2016","journal-title":"J Clin Diagn Res."},{"key":"B23","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1002\/pbc.26211","article-title":"Synovial sarcoma presenting as colonic intussusception in a child","volume":"64","author":"Eid","year":"2017","journal-title":"Pediatr Blood Cancer."},{"key":"B24","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1177\/1093526617705271","article-title":"Submucosal colonic lipoblastoma presenting with colo-colonic intussusception in an infant","volume":"21","author":"Brundler","year":"2018","journal-title":"Pediatr Dev Pathol."},{"key":"B25","first-page":"492","article-title":"Colocolic intussusception in a three-year-old child caused by a colonic polyp","volume":"54","author":"Arthur","year":"1990","journal-title":"Conn Med."},{"key":"B26","first-page":"517","article-title":"Colonic intussusceptions in children","volume":"54","author":"Davies","year":"1978","journal-title":"S Afr Med J."},{"key":"B27","doi-asserted-by":"publisher","first-page":"1636","DOI":"10.1016\/j.jacr.2019.04.011","article-title":"Imaging intussusception in children's hospitals in the United States: trends, outcomes, and costs","volume":"16","author":"Otero","year":"2019","journal-title":"J Am Coll Radiol."},{"key":"B28","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1097\/PEC.0000000000000548","article-title":"Intussusception in children presenting to the emergency department: an Asian perspective","volume":"33","author":"Yap Shiyi","year":"2017","journal-title":"Pediatr Emerg Care."},{"key":"B29","doi-asserted-by":"publisher","first-page":"668","DOI":"10.1097\/MPG.0000000000002477","article-title":"Polyp Characteristics of nonsyndromic and potentially syndromic juvenile polyps: a retrospective cohort analysis","volume":"69","author":"Ibrahimi","year":"2019","journal-title":"J Pediatr Gastroenterol Nutr."},{"key":"B30","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1007\/s00247-009-1178-9","article-title":"Intussusception in children: evidence-based diagnosis and treatment","volume":"39","author":"Applegate","year":"2009","journal-title":"Pediatr Radiol."},{"key":"B31","doi-asserted-by":"publisher","first-page":"619","DOI":"10.2214\/ajr.158.3.1739006","article-title":"Plain film diagnosis of intussusception: prevalence of the target sign","volume":"158","author":"Ratcliffe","year":"1992","journal-title":"AJR Am J Roentgenol."},{"key":"B32","first-page":"272","article-title":"Ultrasonographic findings of intussusception in pediatric cases","volume":"13","author":"Ayaz","year":"2011","journal-title":"Med Ultrason."},{"key":"B33","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1016\/0022-3468(76)90289-X","article-title":"Leading points in childhood intussusception","volume":"11","author":"Ein","year":"1976","journal-title":"J Pediatr Surg."},{"key":"B34","doi-asserted-by":"publisher","first-page":"587","DOI":"10.1016\/j.jpedsurg.2020.09.055","article-title":"Management of intussusception in children: A systematic review","volume":"56","author":"Kelley-Quon","year":"2021","journal-title":"J Pediatr Surg."}],"container-title":["Frontiers in Surgery"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fsurg.2022.873624\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,6]],"date-time":"2022-04-06T00:24:13Z","timestamp":1649204653000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fsurg.2022.873624\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,6]]},"references-count":34,"alternative-id":["10.3389\/fsurg.2022.873624"],"URL":"https:\/\/doi.org\/10.3389\/fsurg.2022.873624","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-1197972\/v1","asserted-by":"object"}]},"ISSN":["2296-875X"],"issn-type":[{"value":"2296-875X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,6]]},"article-number":"873624"}}