{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:30:29Z","timestamp":1787027429125,"version":"build-2736575974"},"reference-count":27,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,5,31]],"date-time":"2022-05-31T00:00:00Z","timestamp":1653955200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Surg."],"abstract":"<jats:p>Ectopic parathyroid adenoma, though rare, is one of the causes of persistent hyperparathyroidism and recurrence of hyperparathyroidism. Ectopic parathyroid glands can be seen in thymus, thyroid, and mediastinum. However, ectopic parathyroid adenoma occurred in the posterior superior mediastinum is extremely rare. Here, we report a case of primary hyperparathyroidism caused by ectopic parathyroid adenoma located in the posterior superior mediastinum. Serum parathyroid hormone, calcium, and vitamin D levels of the patient was followed up for one year.<\/jats:p>","DOI":"10.3389\/fsurg.2022.893259","type":"journal-article","created":{"date-parts":[[2022,5,31]],"date-time":"2022-05-31T01:40:52Z","timestamp":1653961252000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Case Report: Primary Hyperparathyroidism due to Posterior Mediastinal Parathyroid Adenoma With One-Year Follow-Up"],"prefix":"10.3389","volume":"9","author":[{"given":"Yi","family":"Shao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingdong","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Lv","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xu","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Sheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2022,5,31]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1016\/j.otohns.2004.10.005","article-title":"A systematic review of the diagnosis and treatment of primary hyperparathyroidism from 1995 to 2003","volume":"132","author":"Ruda","year":"2005","journal-title":"Otolaryngol Head Neck Surg"},{"key":"B2","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1007\/s00268-012-1773-z","article-title":"Incidence and localization of ectopic parathyroid adenomas in previously unexplored patients","volume":"37","author":"Roy","year":"2013","journal-title":"World J Surg"},{"key":"B3","doi-asserted-by":"publisher","first-page":"527","DOI":"10.3978\/j.issn.2225-319X.2015.09.04","article-title":"Video assisted thoracoscopic excision of mediastinal ectopic parathyroid adenomas: a UK regional experience","volume":"4","author":"Amer","year":"2015","journal-title":"Ann Cardiothorac Surg"},{"key":"B4","doi-asserted-by":"publisher","first-page":"2389","DOI":"10.1056\/NEJMcp1106636","article-title":"Clinical practice: primary hyperparathyroidism","volume":"365","author":"Marcocci","year":"2011","journal-title":"N Engl J Med"},{"key":"B5","doi-asserted-by":"publisher","first-page":"176","DOI":"10.3174\/ajnr.A3615","article-title":"4D-CT for preoperative localization of abnormal parathyroid glands in patients with hyperparathyroidism: accuracy and ability to stratify patients by unilateral versus bilateral disease in surgery-naive and re-exploration patients","volume":"35","author":"Kelly","year":"2014","journal-title":"AJNR Am J Neuroradiol"},{"key":"B6","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1002\/ca.21220","article-title":"Anatomy of thyroid and parathyroid glands and neurovascular relations","volume":"25","author":"Mohebati","year":"2012","journal-title":"Clin Anat"},{"key":"B7","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1016\/j.otc.2010.01.001","article-title":"Surgical anatomy of the thyroid and parathyroid glands","volume":"43","author":"Fancy","year":"2010","journal-title":"Otolaryngol Clin North Am"},{"key":"B8","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1097\/00000658-197603000-00010","article-title":"The anatomic basis of parathyroid surgery","volume":"183","author":"Wang","year":"1976","journal-title":"Ann Surg"},{"key":"B9","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1007\/s12565-011-0111-0","article-title":"Parathyroid gland anatomical distribution and relation to anthropometric and demographic parameters: a cadaveric study","volume":"86","author":"Hojaij","year":"2011","journal-title":"Anat Sci Int"},{"key":"B10","doi-asserted-by":"publisher","first-page":"418","DOI":"10.1016\/j.amjsurg.2005.10.049","article-title":"Incidence and location of ectopic abnormal parathyroid glands","volume":"191","author":"Phitayakorn","year":"2006","journal-title":"Am J Surg"},{"key":"B11","doi-asserted-by":"publisher","first-page":"977","DOI":"10.4158\/EP10052","article-title":"Characteristics of ectopic parathyroid glands in 145 cases of primary hyperparathyroidism","volume":"16","author":"Mendoza","year":"2010","journal-title":"Endocr Pract"},{"key":"B12","first-page":"1627","article-title":"Endocrine imaging: parathyroid, adrenal cortex and medulla, and other endocrine tumors. 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