{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T13:18:37Z","timestamp":1787318317764,"version":"build-2736575974"},"reference-count":38,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,10,11]],"date-time":"2022-10-11T00:00:00Z","timestamp":1665446400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003392","name":"Natural Science Foundation of Fujian Province","doi-asserted-by":"publisher","award":["2019J01436"],"award-info":[{"award-number":["2019J01436"]}],"id":[{"id":"10.13039\/501100003392","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Surg."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Transareolar uniportal thoracoscopic extended thymectomy (TUTET) has not been previously reported. We attempted to assess the feasibility and safety of TUTET for male myasthenia gravis (MG) patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and methods<\/jats:title>\n                    <jats:p>From February 2013 to February 2020, 46 men with MG underwent TUTET. All patients were followed up for 12\u201384 months postoperatively by clinic visits or telephone\/e-mail interviews.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>All surgeries were completed successfully, with an average operation time of 72.6\u2005min. The mean length of transareolar uniportal incision was 3.0\u2009\u00b1\u20090.4\u2005cm, and the mean postoperative cosmetic score was 3.1\u2009\u00b1\u20090.5 at discharge. Three months postoperatively, no patients had an apparent surgical scar on the chest wall or complained of postoperative pain. Substantial amelioration of the disease was achieved in a short period, and several benefits were clear. At the 1-year follow-up, all patients showed a good cosmetic effect and high satisfaction.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>TUTET is an effective and safe way for men with MG. The uniportal incision is hidden in the areola with sound cosmetic effects. We believe that TUTET is an acceptable procedure for extended thymectomy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fsurg.2022.914677","type":"journal-article","created":{"date-parts":[[2022,10,11]],"date-time":"2022-10-11T02:32:02Z","timestamp":1665455522000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Transareolar uniportal thoracoscopic extended thymectomy for patients with myasthenia gravis"],"prefix":"10.3389","volume":"9","author":[{"given":"Jianbo","family":"Lin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nanlong","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xu","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fancai","family":"Lai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2022,10,11]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1016\/j.athoracsur.2010.08.041","article-title":"Comparative clinical features and immune responses after extended thymectomy for myasthenia gravis in patients with atrophic versus hyperplastic thymus","volume":"91","author":"Chen","year":"2011","journal-title":"Ann Thorac Surg"},{"key":"B2","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1016\/S0003-4975(01)02678-9","article-title":"Predictors of outcome in thymectomy for myasthenia gravis","volume":"72","author":"Budde","year":"2001","journal-title":"Ann Thorac Surg"},{"key":"B3","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1016\/S1010-7940(02)00744-3","article-title":"Predictors of clinical outcome following extended thymectomy in myasthenia gravis","volume":"23","author":"Ozdemir","year":"2003","journal-title":"Eur J Cardiothorac Surg"},{"key":"B4","doi-asserted-by":"publisher","first-page":"853","DOI":"10.1016\/S0003-4975(96)00376-1","article-title":"Extended thymectomy for myasthenia gravis patients: a 20-year review","volume":"62","author":"Masaoka","year":"1996","journal-title":"Ann Thorac Surg"},{"key":"B5","doi-asserted-by":"publisher","first-page":"511","DOI":"10.1056\/NEJMoa1602489","article-title":"Randomized trial of thymectomy in myasthenia gravis","volume":"375","author":"Wolfe","year":"2016","journal-title":"N Engl J Med"},{"key":"B6","doi-asserted-by":"publisher","first-page":"610","DOI":"10.1093\/icvts\/ivv176","article-title":"Unilateral video-assisted thoracoscopic extended thymectomy offers long-term outcomes equivalent to that of the bilateral approach in the treatment of non-thymomatous myasthenia gravis","volume":"21","author":"Liu","year":"2015","journal-title":"Interact Cardiovasc Thorac Surg"},{"key":"B7","doi-asserted-by":"publisher","first-page":"849","DOI":"10.1007\/s00464-010-1280-y","article-title":"Bilateral video-assisted thoracoscopic thymectomy has a surgical extent similar to that of transsternal extended thymectomy with more favorable early surgical outcomes for myasthenia gravis patients","volume":"25","author":"Lee","year":"2011","journal-title":"Surg Endosc"},{"key":"B8","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1016\/j.ejcts.2009.05.027","article-title":"Thymectomy for non-thymomatous myasthenia gravis: a comparison of surgical methods and analysis of prognostic factors","volume":"37","author":"Lin","year":"2010","journal-title":"Eur J Cardiothorac Surg"},{"key":"B9","doi-asserted-by":"publisher","first-page":"999","DOI":"10.1016\/j.jtcvs.2016.06.023","article-title":"Transareolar pulmonary bullectomy for primary spontaneous pneumothorax","volume":"152","author":"Lin","year":"2016","journal-title":"J Thorac Cardiovasc Surg"},{"key":"B10","doi-asserted-by":"publisher","first-page":"644","DOI":"10.1093\/icvts\/ivv224","article-title":"Single-port video-assisted thoracoscopic mediastinal tumour resection","volume":"21","author":"Wu","year":"2015","journal-title":"Interact Cardiovasc Thorac Surg"},{"key":"B11","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1016\/S0003-4975(00)01595-2","article-title":"Myasthenia gravis: recommendations for clinical research standards. 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