{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T16:17:31Z","timestamp":1791044251048,"version":"4.1.0"},"reference-count":22,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,2,17]],"date-time":"2023-02-17T00:00:00Z","timestamp":1676592000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Surg."],"abstract":"<jats:sec><jats:title>Study Objective<\/jats:title><jats:p>To explore how to improve the treatment, and prognosis of ovarian pregnancy (OP).<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients<\/jats:title><jats:p>A total of 111 OP patients, one of the patients suffered from OP twice.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In this study, 112 OP cases confirmed by postoperative pathology were retrospectively analyzed. Common risk factors for OP were previous abdominal surgery (39.29%) and intrauterine device use (18.75%). We modified the ultrasonic classification into four types: gestational sac type, hematoma type I, hematoma type II, and intraperitoneal hemorrhage type. Among these four types, the proportion of patients who underwent emergency surgery as initial treatment after admission was 68.75%, 10.00%, 92.00%, and 81.36%, respectively. The treatment for hematoma type I patients was often delayed. The rate of OP rupture was 86.61%. All methotrexate therapy for OP patients failed. All these 112 cases underwent surgery treatment finally. The surgical procedures were pregnancy ectomy and ovarian reconstruction by laparoscopy or laparotomy. No significant differences were observed in the operation time or intraoperative blood loss between laparoscopy and laparotomy. Laparoscopy showed less influence on patients regarding length of hospital stay and postoperative fever than laparotomy. Further, 49 patients who desired fertility were followed up over 3 years. Among them, 24 (48.98%) experienced spontaneous intrauterine pregnancy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Among the four modified ultrasonic classifications, hematoma type I was associated with more delays in surgical time. Laparoscopic surgery was a better choice for OP treatment. The reproductive prognosis of OP patients was promising.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fsurg.2023.1062228","type":"journal-article","created":{"date-parts":[[2023,2,17]],"date-time":"2023-02-17T09:09:02Z","timestamp":1676624942000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":10,"title":["Case Report: Ovarian pregnancy, a rare but lethal condition: An analysis of 112 cases"],"prefix":"10.3389","volume":"10","author":[{"given":"Mengyuan","family":"Shao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyi","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2023,2,17]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1016\/j.ijgo.2011.02.013","article-title":"Pregnancy outcomes after surgical treatment of ovarian pregnancy","volume":"114","author":"Koo","year":"2011","journal-title":"Int J Gynaecol Obstet"},{"key":"B2","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1186\/s12958-021-00761-w","article-title":"Ectopic pregnancy: a single-center experience over ten years","volume":"19","author":"Al Naimi","year":"2021","journal-title":"Reprod Biol Endocrinol"},{"key":"B3","first-page":"169","article-title":"Laparoscopic management of ovarian pregnancy","volume":"12","author":"Tinelli","year":"2008","journal-title":"JSLS"},{"key":"B4","doi-asserted-by":"publisher","first-page":"1823","DOI":"10.1111\/jog.12790","article-title":"Ovarian pregnancy associated with a fresh blastocyst transfer following in vitro fertilization","volume":"41","author":"Ishikawa","year":"2015","journal-title":"J Obstet Gynaecol Res"},{"key":"B5","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1111\/jog.12146","article-title":"Unusual ectopic pregnancies: a retrospective analysis of 65 cases","volume":"40","author":"Shan","year":"2014","journal-title":"J Obstet Gynaecol Res"},{"key":"B6","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1097\/PGP.0000000000000482","article-title":"Primary ovarian pregnancy: a case series and analysis","volume":"38","author":"Wang","year":"2019","journal-title":"Int J Gynecol Pathol"},{"key":"B7","doi-asserted-by":"publisher","first-page":"e006447","DOI":"10.1136\/bmjopen-2014-006447","article-title":"Risk factors and clinical features of ovarian pregnancy: a case-control study","volume":"4","author":"Zhu","year":"2014","journal-title":"BMJ Open"},{"key":"B8","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1016\/j.ejogrb.2010.08.016","article-title":"Risk factors for rupture in tubal ectopic pregnancy: definition of the clinical findings","volume":"154","author":"Goksedef","year":"2011","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"B9","doi-asserted-by":"publisher","first-page":"574","DOI":"10.5114\/wiitm.2015.55893","article-title":"Successful laparoscopic management of a rare complication after embryo transfer: ovarian pregnancy. 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