{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T16:18:50Z","timestamp":1784823530499,"version":"3.55.0"},"reference-count":20,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T00:00:00Z","timestamp":1682467200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100012542","name":"Sichuan Province Science and Technology Support Program","doi-asserted-by":"publisher","award":["2018SZ0400"],"award-info":[{"award-number":["2018SZ0400"]}],"id":[{"id":"10.13039\/100012542","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008402","name":"Science and Technology Development Fund of the Hospital of Chengdu University of Traditional Chinese Medicine","doi-asserted-by":"publisher","award":["20EJ03"],"award-info":[{"award-number":["20EJ03"]}],"id":[{"id":"10.13039\/501100008402","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Surg."],"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>The objectives of this study were to analyze rhinogenic headache, i.e., noninflammatory frontal sinus headache, a headache caused by bony obstruction of the frontal sinus drainage channels that receives relatively insufficient attention clinically, and to propose endoscopic frontal sinus opening surgery as a treatment based on the etiology.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Case series.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>From the data of patients with noninflammatory frontal sinus headache who underwent endoscopic frontal sinus surgery in Hospital of Chengdu University of Traditional Chinese Medicine during 2016\u20132021, data for three cases with detailed postoperative follow-up data were extracted for case series reports.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This report provides detailed information on three patients with noninflammatory frontal sinusitis headache. Treatment options include surgery and rechecking, with the visual analogue scale (VAS) scores of preoperative and postoperative symptoms, CT, and endoscopic images. Three patients had common characteristics: the clinical manifestations were recurrent or persistent with pain and discomfort in the forehead area, but there was no nasal obstruction or runny nose; the paranasal sinus CT revealed no signs of inflammation in the sinuses but suggested bony obstruction of the drainage channel of the frontal sinus.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>All three patients had recovery from headache, nasal mucosal recovery, and patent frontal sinus drainage. The recurrence rate of forehead tightness and discomfort or pain was 0.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Noninflammatory frontal sinus headache does exist. Endoscopic frontal sinus opening surgery is a feasible treatment modality that can largely or even completely eliminate the stuffy swelling and pain in the forehead. The diagnosis and surgical indications for this disease are based on a combination of anatomical abnormalities and clinical symptoms.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fsurg.2023.1132450","type":"journal-article","created":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T05:25:25Z","timestamp":1682486725000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Case report: Endoscopic frontal sinus opening surgery for noninflammatory frontal sinus headache: A short case series"],"prefix":"10.3389","volume":"10","author":[{"given":"Yan","family":"Xie","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiqi","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wanling","family":"Cui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dandi","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feifei","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fangqi","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rongrong","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenyu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luyun","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2023,4,26]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"103113","DOI":"10.1016\/j.amjoto.2021.103113","article-title":"Rhinogenic and sinus headache\u2014literature review","volume":"42","author":"Bernichi","year":"2021","journal-title":"Am J Otolaryngol"},{"key":"B2","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1177\/0333102417738202","article-title":"The international classification of headache disorders, 3rd edition","volume":"38","author":"Arnold","year":"2018","journal-title":"Cephalalgia"},{"key":"B3","doi-asserted-by":"publisher","first-page":"481","DOI":"10.13201\/j.issn.1001-1781.2012.11.004","article-title":"Diagnosis and differential diagnosis of rhinogenic headache","volume":"26","author":"Zheng","year":"2012","journal-title":"J Clin Otolaryngol Head Neck Surg"},{"key":"B4","first-page":"80","article-title":"Diagnosis and treatment of 85 cases of rhinogenic headache","volume":"1","author":"Lei","year":"2013","journal-title":"Chin J Otolaryngol Skull Base Surg"},{"key":"B5","first-page":"1897","article-title":"Analysis of clinical causes of non-inflammatory rhinogenic headache","volume":"23","author":"Guinian","year":"2007","journal-title":"J Pract Med"},{"key":"B6","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1111\/j.1526-4610.2006.00688.x","article-title":"The Sinus, Allergy and Migraine Study (SAMS): CME","volume":"47","author":"Eross","year":"2007","journal-title":"Headache"},{"key":"B7","author":"Hongli","year":""},{"key":"B8","doi-asserted-by":"publisher","first-page":"497","DOI":"10.1016\/S0194-5998(03)01581-X","article-title":"The agger nasi cell: the key to understanding the anatomy of the frontal recess","volume":"129","author":"Wormald","year":"2003","journal-title":"Otolaryngol Head Neck Surg"},{"key":"B9","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1007\/s12070-017-1086-5","article-title":"The role of balloon sinuplasty in the treatment of vacuum rhinogenic headache","volume":"69","author":"Marzetti","year":"2017","journal-title":"Indian J Otolaryngol Head Neck Surg"},{"key":"B10","article-title":"Anatomical factors causing simple rhinogenic headache in nasal endoscopic surgery","volume":"18","author":"ChengLiang","year":"2004","journal-title":"J Shandong Univ School Basic Med"},{"key":"B11","first-page":"1170","article-title":"Mechanisms of the substance P and painful disease","volume":"8","author":"Xiaochan","year":"2018","journal-title":"World J Integr Tradit Western Med"},{"key":"B12","doi-asserted-by":"publisher","first-page":"963","DOI":"10.1111\/head.14142","article-title":"Nerve block as neuropathic pain treatment for the great auricular nerve neuropathy: a case report","volume":"61","author":"Moreno","year":"2021","journal-title":"Headache J Head Face Pain"},{"key":"B13","doi-asserted-by":"publisher","first-page":"e228","DOI":"10.1097\/SCS.0000000000004211","article-title":"Rhinogenic contact point headache: surgical treatment versus medical treatment","volume":"29","author":"La Mantia","year":"2018","journal-title":"J Craniofac Surg"},{"key":"B14","doi-asserted-by":"publisher","first-page":"159","DOI":"10.2478\/afmnai-2013-0008","article-title":"Results of functional endoscopic sinus surgery in patients with mucosal contact points suffering from chronic daily headache non-responding to medications","volume":"30","author":"Madani","year":"2013","journal-title":"Acta Fac Med Naissensis"},{"key":"B15","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1177\/000348940611500407","article-title":"Safety and feasibility of balloon catheter dilation of paranasal sinus ostia: a preliminary investigation","volume":"115","author":"Brown","year":"2006","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"B16","doi-asserted-by":"publisher","first-page":"638","DOI":"10.1177\/0003489415573959","article-title":"Endoscopic management of chronic frontal sinusitis: prospective quality of life analysis","volume":"124","author":"Askar","year":"2015","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"B17","doi-asserted-by":"publisher","first-page":"1229","DOI":"10.1002\/lary.20168","article-title":"Long-term frontal sinus patency after endoscopic frontal sinusotomy","volume":"119","author":"Yvonne","year":"2009","journal-title":"Laryngoscope"},{"key":"B18","doi-asserted-by":"publisher","first-page":"404","DOI":"10.1002\/alr.21112","article-title":"Office-based balloon sinus dilation: a prospective, multicenter study of 203 patients","volume":"3","author":"Boris","year":"2013","journal-title":"Int Forum Allergy Rhinol"},{"key":"B19","first-page":"215","article-title":"Progress of sinus balloon dilatation in the treatment of chronic sinusitis","volume":"28","author":"Xiaoying","year":"2013","journal-title":"Guangming Tradit Chin Med"},{"key":"B20","first-page":"108","article-title":"Treatment of chronic frontal sinusitis by endoscopic minimally invasive surgery","volume":"39","author":"Jianbo","year":"2004","journal-title":"Chin J Otolaryngol"}],"container-title":["Frontiers in Surgery"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fsurg.2023.1132450\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T05:25:33Z","timestamp":1682486733000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fsurg.2023.1132450\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,26]]},"references-count":20,"alternative-id":["10.3389\/fsurg.2023.1132450"],"URL":"https:\/\/doi.org\/10.3389\/fsurg.2023.1132450","relation":{},"ISSN":["2296-875X"],"issn-type":[{"value":"2296-875X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,4,26]]},"article-number":"1132450"}}